Biomedical subjects
Publications and source records attributed to C Kanitakis.
A recent familial case of hereditary epidermolytic palmoplantar keratoderma (Vörner type) that was treated with orally administered etretinate is reported herein. A review of the literature with regard to the clinical, genetic, and laboratory features of this rare genodermatosis is also presented.
The distribution of 30 HLA antigens was studied in 48 patients with Pityriasis Versicolor and 134 controls. No significant deviations were found in the patient group after correction for the number of antigens tested.
We report an exceptional case of multinodular plaque-type blue nevus in a 63-year-old woman, located on the presternal region. The lesions appeared at the age of 25 years on an achromic area. The probable clinical diagnosis was that of a pigmentary nevus. Histopathological examination showed a partially cellular blue nevus with a superficial topography and a neuroid arrangement. On this occasion, a review of the literature and a study of this peculiar form of blue nevus are made.
A case of lichen purpuricus in a 19-year-old male is reported. The eruption appeared on the left hand 4 years ago, disappeared spontaneously after 2 years and reappeared later. It was characterized by a few asymptomatic, dark-red colored macules and papules, scattered and not confluent in a plaque. No clinical diagnosis could be made. Histopathological examination showed the presence in the upper dermis of a dense cellular infiltrate and of hemosiderin granules. The infiltrate was composed of lymphocytes, histiocytes and numerous extravasated red cells; it had an bandlike arrangement and was generally separated from the epidermis. On this occasion, a review of the literature and a study of the clinical and histopathological features, as well as of the etiopathogenesis of this dermatosis, are made.
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The results of direct immunofluorescent staining from patients with different types of lichen planus are reported. Total antiserum, IgA, IgG, IgM, C1B/C1A and Fg antiserums were used. Immunoglobulin deposits were noted on colloid bodies, on the epidermal basement ,nd the walls of the papillary vessels.
We report 2 exceptional cases of solitary nodular calcinosis of the skin, the first to be observed in Greece, with the clinical appearance of cutaneous horn and milium respectively. The latter clinical form has not been described in the literature. Histopathological examination of the first case shows the presence of numerous calcified concretions in the papillary dermis, directly beneath the epidermis, which is intensely hyperkeratotic and papillomatous. The calcified concretions are also seen in the lymphatic capillaries, the intraepidermal sweat ducts and horny layer; at a site they perforate the epidermis and penetrate in a sweat pore. The stroma presents an angiomatous appearance. Histopathological examination of the second case shows the presence of two well demarcated calcified masses in the upper dermis, the larger one being subepidermal, the other one being situated a little further from the epidermis. The smaller mass contains numerous hair shafts and is partially surrounded by a true epithelial wall, similar to that of an epidermal cyst.
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