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Biomedical subjects

C Juliet

Publications and source records attributed to C Juliet.

9 recordsLinked to original sources
PubMed1996

[Lyme disease in Chile. Prevalence study in selected groups].

BACKGROUND: The prevalence of Lyme disease in Chile is unknown. AIM: To study the existence and epidemiology of Lyme disease in Chile. PATIENTS AND METHODS: One hundred eighteen patients with signs or symptoms suggestive of Lyme disease were studied. Antibodies against Borrelia burgdorferi were measured using ELISA and indirect immunofluorescence screening tests. Positive cases were confirmed with ELISA using a purified antigen and Western Blot analysis. Human biological samples and ticks were cultured in BSK-H medium. RESULTS: Five patients, three with dermatological manifestations and two with facial palsy and other neurological symptoms, had antibodies against Borrelia, measured by ELISA and indirect immunofluorescence. However the presence of IgM antibodies by ELISA using purified antigen, was confirmed in only one case. All sera and cerebrospinal fluids were negative on Western Blot Analysis. No plasma, skin, CSF or thick culture yielded Borrelia CONCLUSIONS: We could not confirm the existence of Lyme disease in Chile. Positive screening with negative confirmatory test suggests false positive non-specific reactivity or that local Borrelia are antigenically different compared to North American strains.

Adolescent↗
PubMed1995

[In vitro comparative activity (E test) of sparfloxacin and other 8 antimicrobial agents against bacteria isolated from patients with respiratory infections acquired in the community].

Sparfloxacin is a new antimicrobial that, while maintaining a good activity against gram negative bacilli, has a better in vitro activity against gram positive bacteria such as S pneumoniae, intracellular pathogens and anaerobic bacteria. The aim of this work was to study the in vitro activity of sparfloxacin against bacteria isolated from patients with community acquired respiratory infections between October 1994 and January 1995. Using the E-test technique, we studied the susceptibility to sparfloxacin, ciprofloxacin, ampicillin, amoxicillin/clavulanic acid, cefuroxime, cefotaxime, erythromycin, methicillin and nalidixic acid of 50 strains of S pneumoniae, 50 strains of H. influenzae, 50 strains of S aureus and 50 strains of S pyogenes. Sparfloxacin was active against 100% of S pneumoniae, H influenzae and S pyogenes strains. Twenty two percent of S aureus strains were resistant and the MIC 90 was 12 micrograms/ml. Sparfloxacin showed the best in vitro activity against H influenzae and S aureus, a similar activity with ampicillin and cefotaxime against S pneumoniae and a similar activity with ampicillin but superior to all other studied antimicrobial against S pyogenes. It is concluded that sparfloxacin is a good antimicrobial for bacteria isolated from patients with respiratory infections.

Anti-Bacterial Agents↗
PubMed1993

[Seroprevalence of Legionella pneumophila infection in healthy, adults from Santiago, Chile].

In order to investigate the L pneumophila seroprevalence in healthy adult population of Santiago, Chile, a serologic survey of antibodies to serogroups 1 through G was performed. Sera of 100 blood donors were studied with the indirect fluorescent antibody method. Positive results (> or = 1.64) were obtained in five samples. Titres > or = 1:128 were not observed. We conclude that the seroprevalence of L pneumophila in Santiago is 5% and that a single titre > or = 1:256 suggests the diagnosis of legionellosis. The low seroprevalence in Santiago is in agreement with the few cases of legionellosis reported.

Adult↗
PubMed1982

[Evolution of bacteria in hospital (author's transl)].

This study reports the evolution of bacterial ecology during twelve years in a general hospital : prevalence of the different species isolated and their resistance to antibiotics. It appears, in the etiology of serious infections, a great stability in the repartition of bacterial groups responsible. Likewise, the evolution of bacterial resistance during this period did not show a gradual increase. A certain balance seems to occur in function of local conditions, among which a controlled use of antibiotics is certainly an important factor.

Adult↗