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C Jenssen

Publications and source records attributed to C Jenssen.

3 recordsLinked to original sources

[Endoscopic ultrasound in chronic pancreatitis].

Endoscopic ultrasound has continuously gained importance and has proven to be of clinical value in patients with chronic pancreatitis. In addition, the much lower complication rate when compared to ERCP has to be recognised. Some authors have indicated that endoscopic ultrasound in the evaluation of chronic pancreatitis is the imaging method of choice, depending on both ductal and parenchymal criteria, but there are still some limitations. The two major limitations of EUS preventing it being the "gold standard" in patients with chronic pancreatitis are the lack of standard criteria to be used, and adequate education. Endoscopic ultrasound is difficult to learn and therefore teaching has to be standardised. A general acceptance of the staging of chronic pancreatitis using a catalogue based on criteria compatible to the Cambridge classification is required. Difficulties in evaluating parenchymal criteria with the exception of "indicative" calcifications, depend on the differentiation of the normal ageing process from sequelae of acute pancreatic, ethyl-toxic fibrosis and early stages of chronic pancreatitis. In addition, the differentiation of hypoechoic and cystic lesions as inflammatory changes or neoplastic tumours is still difficult; complementary imaging methods also have low sensitivity in this area. In conclusion, there is no doubt that endoscopic ultrasound has proven to be of value using an interdisciplinary approach in the evaluation and therapy of pseudocysts, peripancreatic necrosis, and pancreatic and bile duct obstruction.

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Germany↗

Partial compensation of sexual receptivity deficits in female rats with bilateral lesions of the hypothalamic ventromedial nucleus by transplants of fetal mediobasal hypothalamic tissue.

Bilateral aspiration as well as bilateral electrolytic lesions of the hypothalamic ventromedial nucleus (VMN) in ovariectomized, adult female rats treated with testosterone or estrogen resulted in a long-lasting decrease of sexual receptivity. Fetal mediobasal hypothalamic (MBH) tissue was grafted successfully to the site of VMN lesions. The following presuppositions for a sufficient rate of long-term survival of the grafts could be defined: (1) careful lesioning and minimalizing of damage to the surrounding tissues, (2) high vitality of the donor fetuses, (3) delay of transplantation after lesioning, and (4) testosterone treatment of the recipient animals at an early stage of graft development. In rats with surviving MBH grafts the receptivity deficits resulting from bilateral aspiration of the VMN were compensated partially.

Animals↗