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Biomedical subjects

C J Young

Publications and source records attributed to C J Young.

6 recordsLinked to original sources
PubMed1992

Living with a heart transplant: long-term adjustment.

The number of heart transplants performed worldwide has increased greatly in the past 10 years, and survival rates will continue to improve with the introduction of new immunosuppressive therapies. With this improved lifespan outlook, the experience of living with a heart transplant needs to be understood as a chronic condition. Twenty-nine recipients who were a minimum of 5 months post-transplantation (mean 22 months) and 23 significant others were interviewed twice 6 months apart using close-ended and open-ended questions developed from the Common Sense Model of health beliefs. Results suggest that although life improved for the majority post-transplantation, recipients continue to experience work problems, financial burdens, family role changes, lifestyle changes, and side effects associated with long-term drug treatment.

Adaptation, Psychological↗
PubMed1990

Complete system control: an object-oriented approach.

This paper discusses some of the principles for complete system control for automated multiparameter haematology instruments. A method of analysing the control requirements is used, object-oriented flow diagramming, that combines concepts and notation from object-oriented programming with graphical flow diagramming to produce a model of a haematology instrument's reagent and sample flow during sample analysis. The model is used to analyse the control materials and control mechanisms for components, subsystems and the integrated system. The steps in the method are illustrated using two examples: the cyanmethaemoglobin method and the Coulter VCS leukocyte differential counter.

Hematology↗
PubMedDate not supplied

[Ecology of leishmaniasis in the south of France. 11. Canine leishmaniasis: successful experimental transmission from dog to dog by the bite of Phlebotomus ariasi Tonnoir, 1921 (author's transl)].

As part of a study of visceral leishmaniasis in the Cévennes in southern France, an infection was transmitted from dog to dog by the bite of a single sandfly, Phlebotomus ariasi Tonnoir, 1921. The role of this species as a vector, suspected from earlier studies, is, therefore, confirmed. Twenty female sandflies, which had engorged on a naturally infected dog 23 +/- 2 days previously were put with a healthy dog which, after an incubation period of 15 months, developed viscero-cutaneous leishmaniasis. In dissections of the sandflies immediately after contact with the experimental dog, it was found that only one had engorged. All of 17 sandflies dissected had midgut infections: 10 of these also had infections in the pharynx. The engorged specimen additionally had parasites in the proboscis, a condition thought by many workers to be necessary for the parasite to be transmitted by bite.

Animals↗
PubMedDate not supplied

[Ecology of leishmaniasis in the south of France. -- 12. Horizontal dispersion of Phlebotomus ariasi Tonnoir, 1921. Preliminary experiments (author's transl)].

By use of mark-release-recapture methods, evidence was obtained of the distance of the dispersion of Phlebotomus ariasi Tonnoir, 1021. Female flies, collected in a valley in the Cévennes mountains (at Roquedur, Gard), were marked with fluorescnt powders, released an then recaptured by searching with ultra-violet lamps. The majority of the flies recapture were among ones given a blood meal shortly before release. Recaptures were made from the second day after release. A number of females migrated with blood in the midgut; their ovaries were up to and including stage V. The distance between the extreme points of recapture was about 1 km, and the maximum recorded distance between points of release and recapture was 750 m. The epidemiological interest of these observations is that, at least in the Cévennes foci, the sandfly as well as the dog must now be considered as capable spreading the pathogenic agent of visceral leishmaniasis.

Animals↗