Search PubMed⌕ Search

Biomedical subjects

C J Thomas

Publications and source records attributed to C J Thomas.

At least 145 records · Page 8Linked to original sources

Spoilage of chicken skin at 2 degrees C: electron microscopic study.

Microscopic techniques were used in conjunction with normal microbiological procedures to examine the development of the spoilage microflora on the skin of chicken carcasses held at 2 degrees C. Pigmented and nonpigmented psychrotrophic pseudomonads were the major spoilage bacteria isolated at all stages of storage examined. The spoilage microflora grow within a liquid film covering the skin surface, as well as in feather follicle shafts. Penetration and disruption of skin tissue were not observed even after onset of organoleptic spoilage. Bacteria were not attached to the skin by extracellular bridging substances. These data suggest a nonspecific histological-microbiological relationship between he spoilage association and the skin substrate.

Animals↗

Attachment of Salmonella spp. to chicken muscle surfaces.

Immersion of chicken muscle fascia in water or physiological saline caused collagen associated with the connective tissue to expand and form a dense network of fibers on the surface. Similar changes were noted for muscle perimysium. Two test strains of Salmonella spp. attached to the collagen fibers only when muscle was immersed for extended times in water. Bacteria did not attach to the fascia or perimysium of muscle that was transiently immersed in suspensions. The presence of sodium chloride in the suspension media prevented firm attachment, whereas saline rinses removed many attached cells.

Animals↗

Contamination of broiler carcass skin during commercial processing procedures: an electron microscopic study.

Scanning and transmission electron microscopy were used in conjunction with normal microbiological cultural techniques to examine some aspects of contamination of broiler carcass skin by bacteria during processing. The autochthonous skin microflora of poultry, before processing, was mainly Micrococcus spp. which were located in accumulations of sebum-like substances on the surface of the stratum corneum. During scalding and plucking, the skin epidermis was removed, and exposed dermal tissue was contaminated by microorganisms from the mechanical plucker and subsequent stages of processing. Major sources of psychrotrophic contamination were the immersion washer and chiller water. Microbial contaminants were found within a fluid film on the skin surface and inside deep skin channels. Skin microtopography and the presence of the liquid film were implicated as major factors controlling contamination during processing.

Animals↗

Spoilage association of chicken skin.

The bacterial succession on the skin of broiler chicken carcasses stored at 2 degrees C was traced, and the ability of representative isolates to produce off-odors was determined by using sterile leg and breast muscle sections. Off-odors were identified by olfactory and chemical means. The inability of peptone-iron agar to detect sulfide-producing strains was noted.

Animals↗

The use of screening investigations in psychiatry.

This is a study of the results of screening tests on all new psychiatric in-patients over a period of one year. Although none of the results indicated definite physical causes for the psychiatric illness, 10 per cent of the tests revealed abnormalities resulting from or co-incidental with the psychiatric illness. Of these abnormal results 61 per cent led to no further investigation or treatment, and the significance of this is discussed.

Aged↗

Continuing medical education: linking the community hospital and the medical school.

Community hospitals and medical schools have different but complementary resources to carry out continuing medical education. To strengthen the educational capabilities of both, a group of community hospitals has been linked to a medical school in a continuing medical education network. A peripatetic educational development team based at the medical school completes the link by helping community hospital physicians identify educational needs and develop educational responses, using both local and medical school experts as faculty. The educational development team provides skills and staffing which no small or moderate-sized community hospital could afford alone. The program is financially feasible for community hospitals and the medical school, does not consume the resources of either, and conserves the time of the community physician and medical school faculty.

California↗

Central papillary atrophy of the tongue and denture stomatitis.

A retrospective study of the epidemiologic data of 4,417 subjects has been undertaken to study the possibility of a link existing between glossal central papillary atrophy (median rhomboid glossitis) and denture stomatitis. Neither the association between glossal central papillary atrophy and denture stomatitis nor the association between glossal central papillary atrophy and denture use was statistically significant. However, the correlation between wearing removable dental prostheses and finding candidal mycelia in smears from these tongue lesions was statistically highly significant. Debilitation caused by general age changes would not appear to predispose to atrophy of the pappillae of the middle portion of the tongue-dorsum.

Atrophy↗

Diphenylhydantoinate-induced hyperplasia of the masticatory mucosa in an edentulous epileptic patient.

Gingival hyperplasia caused by phenytoin sodium is rarely encountered in edentulous persons. A case of generalized palatal hyperplasia is reported in which retained roots and teeth were suspected of having perpetuated a preextraction lesion, whereas a subsequently placed complete denture initiated a midpalatal hyperplasia. The lesion remained in spite of nonuse of the denture for several years.

Adult↗

The in vitro fungicidal properties of Visco-gel, alone and combined with nystatin and amphotericin B.

The in vitro effect of the tissue conditioner Visco-gel, with or without the inclusion of nystatin and amphotericin B, upon Candida albicans, Candida krusei and Candida tropicalis, has been studied. Visco-gel alone was completely inert and would therefore not be used without nystatin in the treatment of a denture stomatitis where a yeast infection was present. Amphotericin B became completely ineffective when mixed with Visco-gel, but in control tests remained very active.

Amphotericin B↗