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Biomedical subjects

C J Shih

Publications and source records attributed to C J Shih.

42 records · Page 3Linked to original sources
PubMed1979

Thermoregulatory sweating in palmar hyperhidrosis before and after upper thoracic sympathectomy.

To assess thermoregulatory sweating in palmar hyperhidrosis, the authors determined the responses of three groups of normal, hyperhidrotic, and denervated subjects to a variety of ambient temperatures (TA's), 22 degrees, 28 degrees, and 41 degrees C. The normal group had no hyperhidrosis, with intact T2-3 ganglia, the hyperhidrotic group had palm hyperhidrosis with intact T2-3 ganglia, and the denervated group had hyperhydrosis treated with T2-3 ganglionectomy. Both groups of hyperhidrotic and denervated subjects maintained oral and mean skin temperatures within normal limits displayed by the normal group over a wide range of TA's tested. The local sweating rate (LSR) of both the palms and the soles of the feet in the hyperhidrotic group was decreased to a minimal level by either the T2-3 ganglionectomy or the subcutaneous administration of atropine sulfate. Furthermore, the denervated group had a significantly lower LSR of both the forehead and the upper chest regions, but showed a higher LSR or both the ventral thigh and the lateral lumbar regions at a TA of 41 degrees C when compared to the LSR of either the normal or the unoperated hyperhidrotic group. The data demonstrate that the surgical removal of both the T-2 and the T-3 ganglia, although producing no alterations in the thermal balance, does produce abnormalities in quantitative distribution of thermoregulatory sweating in man.

Atropine↗
PubMed1978

Thoracic sympathectomy for palmar hyperhidrosis: report of 457 cases.

A thoracic sympathetic ganglionectomy was performed on 457 patients with palmar hyperhidrosis, resulting in a complete cessation of the excessive palmar sweating but not a total abolition of the sweating of the upper extremity, forehead, face, neck, upper chest and upper back. This procedure does not produce a Horner's syndrome. The present data provide evidence that sympathetic pathways for controlling sweating of the above-mentioned skin areas come mainly through the second thoracic ganglion, and therefore from the spinal cord segment below T1 in man.

Adolescent↗
PubMedDate not supplied

Effects of stellate ganglionectomy on the cat cardiovascular function.

The effects of stellate ganglionectomy on cardiovascular function were assessed in pentobarbital-anesthetized cats. A right stellectomy produced much more profound bradycardiac effects than a left stellectomy. This finding demonstrated that the stellate ganglion exerted a lateralized influence on heart beat in the cat. The cardiovascular response of intact cats to phase 4 (overshoot) of the Valsalva-like maneuver (VM) was reflex bradycardia. In response to VM, however, reflex bradycardia was completely abolished by a right or bilateral stellectomy, or by pretreatment with propranolol, but not by a left stellectomy alone or with phentolamine. The data indicated that the right stellate ganglion in cats makes a major contribution to cardiovascular control, especially over reflex bradycardia mechanisms.

Animals↗