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Biomedical subjects

C J Quirk

Publications and source records attributed to C J Quirk.

9 recordsLinked to original sources
PubMed2000

Topical applications and perioral dermatitis.

Perioral dermatitis (POD) is a common dermatosis and is considered by most dermatologists to be increasing in incidence. An Australia-wide, questionnaire-based study investigating the aetiology of POD was conducted, with particular emphasis on the significance of cosmetic use. One hundred and thirty-three cases were obtained from dermatologists across Australia and were compared with 99 randomly selected controls who were matched for age and sex. Application of foundation, in addition to moisturizer and night cream resulted in a 13-fold increased risk for POD (odds ratio 13.5; P < 0.001). The combination of moisturizer and foundation was associated with a lesser but significantly increased risk for POD (odds ratio 2.9; P = 0.017). Moisturizer alone was not associated with an increased risk of POD. These findings suggest that cosmetic preparations play a vital role in the aetiology of POD, perhaps by an occlusive mechanism. In 83% of cases, topical steroid application to the face occurred after the development of a facial rash.

Adolescent↗
PubMed1998

Hypertrophic lichen planus mimicking squamous cell carcinoma.

An 87-year-old female presented with a 3 month history of hyperkeratotic nodules on her left shin. An initial clinical and histological diagnosis of multiple squamous cell carcinomas on the left shin was made. Review of the biopsy, however, showed hypertrophic lichen planus with pseudoepitheliomatous hyperplasia. Typical lichen planus was seen affecting the oral mucosa, nails and skin elsewhere.

Aged↗
PubMed1998

Brachioradial pruritus and cervical spine manipulation.

Brachioradial pruritus (BRP) causes significant morbidity in the majority of patients for whom no effective treatment is found. Chronic ultraviolet radiation exposure has usually been cited as the cause, but nerve damage from cervical spine disease has also been implicated. We report on a small retrospective exploratory study, conducted by questionnaire, of a group of patients who were treated with a specific cervical spine manipulation. Ten of 14 patients reported resolution of symptoms following manipulative treatment. All six patients who had had previous cervical spine disease responded to manipulation, as did half the remaining eight patients who had no previous history of neck symptoms. Although patients with BRP, by definition, share similar symptoms, the aetiology is almost certainly multifactorial. Prospective studies looking for cervical spine disease, as well as assessment of this particular method of cervical spine manipulation as a treatment modality for BRP, should be considered.

Adult↗
PubMed1986

Epithelioid sarcoma. A diagnostic problem.

Twelve cases of epithelioid sarcoma have been reviewed, illustrating the diagnostic problems for which this rare tumor has become notorious and demonstrating varied rates of tumor progression. The histological features most helpful to the distinction of epithelioid sarcoma from other nodular skin lesions, including benign conditions such as rheumatoid nodule and granuloma annulare, are discussed. The ultrastructural appearances of two cases were similar to immature mesenchymal tissue.

Adolescent↗
PubMed1980

Transient acantholytic dermatosis.

A series of twenty-four cases of transient acantholytic dermatosis (TAD) is presented. All patients were male and their eruptions tended to be more persistent than those of previously reported cases. The epidermal changes included four patterns of acantholysis, of which the pemphigus-like pattern was associated with the more persistent eruptions. Although twenty-three of the twenty-four patients had other actinic-associated skin lesions, no direct relationship between the onset of TAD and episodes of excessive sun exposure was found. Oral vitamin A treatment has been effective in some cases.

Acantholysis↗