Search PubMed⌕ Search

Biomedical subjects

C J Lucas

Publications and source records attributed to C J Lucas.

At least 55 records · Page 3Linked to original sources
PubMed1977

Personality correlates of study difficulty and academic performance in university students. I. The Middlesex Hospital Questionnaire and Dynamic Personality Inventory.

The personality correlates of study difficulty and academic performance in university students have been measured in terms of psychiatric symptomatology and premorbid characteristics. The UCLSQ, MHQ and DPI were administered to two groups of male and female students presenting at an health centre: one (n = 72) of patients seeking psychological help, the other (n = 73) a control group. Significant differences between the two groups were formed on the MHQ, confirming previous results; and these were supplemented by differences on the DPI. Motivational and psychoneurotic components of study difficulty were significantly related to MHQ scores in both groups. DPI scores were more closely related to study difficulty in the patients than controls; and served particularly to characterize their sylbism and work satisfaction. The DPI added to the picture of a subgroup of students observed both in an earlier and the present study: academically successful patients scoring high on phobic anxiety.

Achievement↗
PubMed1977

Personality correlates of study difficulty and academic performance in university students. II. Conscience and self-esteem.

Scales measuring self-esteem and conscience have been included in a further study of work-related symptoms in students. Two groups were tested: a group of patients attending the UCL Student Health Centre for psychological reasons, and a group of normal controls. Conscience and self-esteem were inversely related to one another. Both tests were reliable and differentiated between the groups. The patients tend to have low self-esteem, high conscience, and to score higher than controls both on neurotic symptoms as such as measured by a personality inventory (MHQ) and as assessed on work-related symptoms measured by our study difficulty questionnaire (UCLSQ). In terms of academic performance, an interesting subgroup of students was delineated who are rated highly by their tutors but who appear subjectively troubled with phobic anxiety, low self-esteem and a harsh conscience structure. The conscience and self-esteem scales, in view of their brevity, acceptable reliability, and in terms of the relationships discussed in this paper, will be retained for further research.

Achievement↗
PubMed1976

Physico-chemical and immunological properties of acid alpha-glucosidase from various human tissues in relation to glycogenosis type II (Pompe's disease).

The physico-chemical and immunological properties of acid alpha-glucosidase from various human tissues have been studied. Heat stability of acid alpha-glucosidase from heart, liver and skeletal muscle is identical, but for kidney some different results are obtained. Identical isoelectrofocussing patterns are found for heart, liver and skeletal muscle. Furthermore, the effect of antiserum against human liver acid alpha-glucosidase on the activity of acid alpha-glucosidase from various tissues is studied. The results are discussed in relation to glycogenosis type II (Pompe's disease).

Antigen-Antibody Reactions↗
PubMed1976

Further observation on study difficulty in university students including 'syllabus-boundess'.

The UCLS questionnaire, in a form modified to include a measure of syllabus-boundness, and a questionnaire to measure psychiatric symptomatology (the MHQ) were administered to two groups of students, one seeking help for emotional problems, the other a control group. Groups were compared on tests, test findings were inter-correlated, and scores were related to academic success. The UCLSQ is confirmed as a reliable research instrument. Principal component analysis again indicates a separation of psychoneurotic and motivational components of study difficulty. Syllabus-boundness ('Sylbism') emerges as a relatively independent trait, with a significant negative relationship to work satisfaction in both groups. MHQ scores again show a positive correlation between phobic anxiety and academic attainment for patients.

Achievement↗
PubMed1975

Tubuloreticular structures in human lymphoid cell lines. A cell biological study.

Human lymphoid cell lines were studied as an experimental model for the spontaneous or induced occurrence of tuburloreticular structures (TRS). It was possible to induce TRS after culturing the EB-3 cell line with 20 mug/ml bromodeoxyuridine (BrUdR) during 96 h. Starvation, culturing at lower temperature (32 degrees) or inhibition of DNA synthesis did not give rise to the production of TRS. The response to BrUdR could be blocked with 60 mug/ml thymidine but not with 60 mug/ml deoxycytidine. The addition of 5 mug/ml cytarabine or the removal of BrUdR at different times resulted in inhibition of TRS induction, indicating that BrUdR had to be incorporated into DNA during at least 48 h. After incorporation, neither the presence of BrUdR nor DNA synthesis was necessary for the production of TRS. These experiments and the finding that in the cell line IHTC-33, which does not produce Epstein-Barr virus associated antigens, TRS were spontaneously present, exclude a correlation between TRS and these antigens. However, the induction of TRS by BrUdR may be related to the activation of another (latent) virus.

Antigens, Viral↗