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Biomedical subjects

C J Long

Publications and source records attributed to C J Long.

At least 55 records · Page 3Linked to original sources

Clinical memory tests and everyday memory.

This study examined the relationship between clinical memory tests and everyday memory abilities. Fifty older adults were given clinical memory tests, a battery of everyday tasks and a self-report questionnaire of memory problems. The interrelationships among these groups of memory assessment measures were studied using Pearson correlations and multivariate canonical analysis. The resulting intercorrelations and canonical variate loadings were low to moderate in overall magnitude. The self-assessment of memory problems had a much lower relationship to everyday and clinical memory tasks. The self-assessment of memory for reading material had the strongest relationship to clinical memory tests. In general, these results moderately support the use of clinical memory tests to predict everyday memory ability.

Journal Article↗

Investigation of the Karnofsky Performance Status as a measure of quality of life.

The Karnofsky Performance Status appears to be the most widely used scale for objective assessment of medical patients' quality of life. Evidence for its reliability and validity is reviewed and new data presented. Tests of inter-rater reliability, concurrent validity, and discriminant validity indicate that, with standardized observational procedures based on a mental status exam, the Karnofsky scale is acceptably reliable and valid as a global measure but it does not adequately capture the conceptual domain of quality of life.

Aged↗

The relationship between neuropsychological functioning and psychopathology in temporal lobe epileptic patients.

With the use of Goldberg's method of Minnesota Multiphasic Personality Inventory (MMPI) analysis, evidence has been recently provided of a positive relationship between psychopathology and deficits in neuropsychological functioning in epileptic patients. The present study attempted to replicate this finding using more precise and appropriate criteria for grouping patients according to severity of neuropsychological impairment. Application of Goldberg's MMPI Rules to 34 temporal lobe epileptic patients grouped according to their neuropsychological status (nonimpaired or impaired) failed to support these findings. Possible reasons for the discrepant results, including differing methodologies and seizure patient characteristics across studies, are discussed.

Adolescent↗

Assessment of level of consciousness following severe neurological insult. A comparison of the psychometric qualities of the Glasgow Coma Scale and the Comprehensive Level of Consciousness Scale.

An alternative method of coma assessment is presented and compared with the Glasgow Coma Scale. The merits of the Comprehensive Level of Consciousness Scale as a research tool are presented. An analysis of 101 consecutive consciousness-impaired patients with their short-term outcome is presented.

Adolescent↗

Psychological sequelae of head trauma.

Head trauma is a significant health care problem. Treatment of the head trauma patient requires assistance from many different disciplines in order to maximize recovery of function. The fact that one fourth or more of head trauma patients are impaired in recovery because of psychological factors suggests that appropriate treatment programs are not being implemented in the United States. Organic factors can produce many of the symptoms reported by head trauma patients. However, these factors are more likely to contribute indirectly to such symptoms, and their influence declines as recovery progresses. Recovery from head trauma follows identifiable stages. During the period of coma, the extent of the organic disturbance is sufficient to impair brain-stem functions. Once consciousness is regained, there is a period of gross memory dysfunction. Coma and posttraumatic amnesia represent the acute phase of recovery, during which patients are often hospitalized and receive intense medical care. Once gross functions return, intense medical care is no longer needed. However, the head trauma victim has not returned to a premorbid status at this point. This phase, between recovery from posttraumatic amnesia and stabilization or recovery of premorbid level of functioning, can best be considered the chronic phase of recovery. The chronic phase of recovery is characterized by defects in cortical functions, including impaired intellectual functions, memory weakness, difficulty in processing complex stimuli, slowed reaction time, and other deficits. While these deficits may not be profound, they do correlate with the severity of injury and the degree of eventual recovery. This observation lends further credence to the presence of underlying disturbance of neurologic functioning. During this chronic phase of recovery, head trauma patients may have made good physical recovery and may feel well enough to return to work. However, they frequently process less information and may experience difficulty with tasks that require attention and effort. Such patients tire rapidly and experience stress symptoms, such as headaches and irritability. These symptoms correspond to environmental demands, but they also reflect underlying neurogenic weaknesses. Emotional sequelae that often emerge during the chronic phase of recovery may be related to the patient's reduced ability to cope with environmental stress. Therefore it is not surprising that emotional sequelae appear to correspond more to environmental demands than to severity of injury per se.(ABSTRACT TRUNCATED AT 400 WORDS)

Amnesia↗

The relationship between surgical outcome and MMPI profiles in chronic pain patients.

Administered the MMPI as part of a comprehensive pain evaluation to 44 patients who were receiving surgery for low back pain. Surgical outcomes then were determined after 6 to 18 months, and the patients were grouped as surgery success (22) or surgery failures (22). MMPI profiles were examined for each group, and while there was a significant difference on the Hs scale, no other mean scores were discriminative. In contrast, when patients were divided into subgroups based upon MMPI profile configurations, a strong relationship existed between subgroup MMPI profile and surgery outcome. Thus, while these data argue against attempting to use group MMPI profiles to predict surgical outcome in patients who are suffering from pain, subgroup profiles do bear a strong relationship with surgery outcome and appear worthy of further investigation.

Adult↗

Improving diagnostic strategies for pain patients.

Any pain experience results from the interaction of biological and functional (namely, psychological and environmental) factors. In some cases functional factors may be primarily responsible for exacerbating and maintaining pain, therefore, the physician should be attentive to a variety of signs that may indicate a significant nonorganic component to the patient's pain. Problems in case management commonly arise when the organic signature is blurred, for pain patients are notoriously resistant to any suggestion that their pain is not purely organic in origin. Clinical experience has shown that the diagnosis and treatment of pain patients can be greatly facilitated by educating the patient about the complex nature of pain and by integrating the assessment of functional factors into the overall diagnostic work-up.

Humans↗

Intervertebral disc surgery: strategies for patient selection to improve surgical outcome.

Eighty patients with severe back or leg pain were assessed by a battery of psychological tests. Functional factors (that is, psychological and behavioral characteristics) though to be contributing to the patient's pain experience were analyzed, and the patient's response to surgery was predicted. Patients were selected for the study on the availability of good follow-up data at 6 months or longer after surgery. The results reveal that the presence of functional factors was not of substantial consideration in the decision for surgical treatment. However, when both the clinical predictions and the subject's response to surgical treatment were rated on the same 0 to 5 scale, it was found that response to surgery could be predicted with 84% accuracy based upon functional data. Few single scores significantly discriminated between success or failure of surgery, and the basis for discrimination was made upon clinical judgment of an array of findings obtained by the functional pain assessment. The results are discussed with regard to a pain model which assumes the presence of an organic-functional pain continuum.

Humans↗

Assessment of the effects of cinglulate gyrus lesions by neuropsychological techniques.

Nineteen psychiatric patients undergoing bilateral cryogenic cingulate cortex lesions were extensively evaluated pre- and postoperatively with objective measures of intelligence, higher cortical functions, memory, and emotional status. Following surgery the patients as a group revealed no significant deterioration of functions; rather, they demonstrated improvement that could be interpreted as the result of decline in anxiety. Investigations of individual revealed that the overall test performance was improved in 13 and substantially unchanged in three, whereas three demonstrated some decline in performance. These results were discussed in terms of the characteristics of the changes across the various tests.

Adult↗