Search PubMed⌕ Search

Biomedical subjects

C J Bentzel

Publications and source records attributed to C J Bentzel.

45 records · Page 3Linked to original sources
PubMed1968

Osmotic volume flow in the proximal tubule of Necturus kidney.

Volume changes due to osmotic flow in the distal portion of proximal tubules of Necturi were measured by the split oil drop technique. In agreement with previous findings no volume flow was induced by NaCl concentrations close to 60 mM. The tubule wall was found to be permeable to plasma electrolytes, which have an apparent reflection coefficient of 0.69. The mean apparent hydraulic conductivity was 0.33 x 10(-11) cm(3)/dyne sec, comparable with other epithelia. A number of lipid-insoluble nonelectrolytes of widely varying molecular size had apparent reflection coefficients of about 0.5. In view of the insensitivity to molecular size it seems likely that apparent reflection coefficients determined from tubular volume changes depend primarily on the porosity of the intercellular barrier closest to the lumen and give little information about the subsequent fate of the test substances.

Animals↗
PubMed1967

Osmotic properties of mitochondria.

The osmotic behavior of rat liver mitochondria has been studied in a sucrose medium. The mitochondria behave like a two compartment system. One compartment is permeable to sucrose and has a volume of 1.22 microl/(mg mitochondrial dry weight) in a 272 milliosmol sucrose medium; the second, inaccessible to sucrose, has a volume of 0.555 microl/mg dry weight) under the same conditions. Part of the water in the sucrose inaccessible space is apparently not free to participate in osmotic phenomena. This volume is 0.272 microl/(mg dry weight) under the same conditions. It is suggested that the osmotically inactive water corresponds to the water of hydration of the mitochondrial macromolecules. The volume of the remainder of the water in the sucrose inaccessible space depends inversely on the osmolality of the medium, as is to be expected. The volume of water in the sucrose accessible space is constant, independent of the osmolality of the medium, as is the volume of the mitochondrial framework plus the nonvolatile solutes.

Animals↗