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Biomedical subjects

C I Neutel

Publications and source records attributed to C I Neutel.

30 records · Page 2Linked to original sources
PubMed1990

Mortality in fishermen: an unusual age distribution.

Age specific standardised mortality ratios (ASMRs) were compared for commercial fishermen under 55 years old and those who were aged 55 and older in the Canadian Atlantic coastal provinces of Nova Scotia, New Brunswick, and Prince Edward Island. The subjects were a cohort of 31,415 fishermen licensed by the Department of Fisheries and Oceans during 1975-83. Mortality was obtained by a computerised linking of the registry of licensed commercial fisheries and the Canadian Mortality Data Base. Fishermen under 55 had ASMRs between 1.4 and 1.7 for death from all causes and around 1.0 for death from non-accidental causes. The older fishermen had ASMRs as low as 0.6 for all causes and non-accidental causes. The same pattern was shown for death from specific causes such as ischaemic heart disease, accidents, and cancer, as well as for different years of entry into the cohort. This pattern differed widely from that of most other occupations. Dividing the cohort into owners and crew members showed that the high mortality ratios at younger ages existed in crew members only. It was concluded that the high death rates for fishermen under 55 had a socioeconomic component.

Accidents, Occupational↗
PubMed1989

Brain tumour mortality in immigrants.

All Canadian deaths due to malignant brain tumour for the years 1970-73 were identified and analysed for country of birth. The years 1970-73 were chosen since in later years country of birth was no longer available for each death. The brain tumour population consisted of 1551 male and 1058 female deaths and matched controls were chosen from deaths due to other causes. Americans who died of brain tumour in Canada had a standardized mortality ratio (SMR) of 1.0 compared to their fellow Americans in the USA. Italian, German, Dutch and British immigrants had SMR between 1.5 and 2.6 compared to rates in their home countries and between 1.24 and 2.09 when compared to Canadian rates. A series of graphs shows the increased risk for male immigrants quite dramatically, and indicates that for females the increases were less pronounced. Further analysis showed that the excess risk is confined to those who were born in Western Europe while their Canadian-born children experienced the same rates as all Canadians. Based on the limited information available, occupation could not be shown to play a role in establishing risk. An attempt was made to pinpoint the years of immigration which showed the greatest risk. It is concluded that the determination of risk of brain tumour has a strong environmental component. The possibilities for identification of this component are discussed.

Adult↗
PubMedDate not supplied

Mortality in commercial fishermen of Atlantic Canada.

All commercial fishermen in the Canadian Maritime provinces (Nova Scotia, New Brunswick, and Prince Edward Island) are registered with the Department of Fisheries and Oceans (DFO). The data obtained by DFO during 1975-1983 on 33,000 fishermen were linked with the Canadian Mortality Data Base by the record linkage procedures in place at Statistics Canada, thus identifying 1,289 male deaths. When Canadian mortality rates were used to calculate the expected number of deaths, the standardized mortality ratio (SMR) was 0.80 for all causes. The rather low SMR can be explained at least partially by "the healthy worker effect". Although the healthy worker effect is generally greater for the younger age groups (i.e. a lower SMR), in this study the all-causes SMR for those under 44 years of age was 1.5. All accidents together showed an SMR of 1.5 which was even higher for the younger age groups (1.75). The most striking finding was the ratio for water transport accidents where observed deaths occurred at 8.5 times the expected rate. SMR for cancers were somewhat high, especially cancer of the pancreas at 1.5. Notable also were the very low rates for respiratory diseases although the younger fishermen still had an SMR greater than one. From a public health point of view, the high accident mortality for all fishermen and high mortality for many causes at the most productive ages associated with this occupation is of concern.

Accidents, Occupational↗
PubMedDate not supplied

Measuring drug effectiveness by default: the case of Bendectin.

In 1983, Bendectin was voluntarily removed from the market by Merrell Dow Pharmaceuticals Inc. because of the many product liability suits pending. Earlier, 10 to 25% of pregnancies were exposed to Bendectin and over the years the drug was used in as many as 33 million pregnancies. The scientific evidence available pointed to the safety of Bendectin. This article considers some of the effects of the withdrawal of the drug. In 1983, hospital admissions for excessive vomiting in pregnancy per thousand live births rose by 37% over 1980-82 ratios and by 50% in 1984. In the United States, hospitalization rose by similar amounts. A rough estimate of excess hospital costs over the years 1983-87 is $16 million for Canada and $73 million for the U.S. Such estimates do not take into consideration other costs, such as extra physician visits, increased absenteeism from work, and the effect on quality of life of the pregnant woman and her family. No decrease in rates of congenital malformations could be shown to offset this increased cost to society.

Abnormalities, Drug-Induced↗