Search PubMed⌕ Search

Biomedical subjects

C Hsu

Publications and source records attributed to C Hsu.

At least 145 records · Page 8Linked to original sources
PubMed1983

Partial hydatidiform mole: ultrasonographic features.

Four patients with partial hyatidiform mole managed at the Queen Mary Hospital, Hong Kong, are described. The diagnosis of blighted ovum or missed abortion was made on the sonographic findings prior to suction evacuation. The dominant features in these cases consisted of a relatively large central transonic area bearing the appearance of an empty gestational sac and surrounded by a thick rim of low-level placenta-like echoes; in contrast with the case of the blighted ovum, a well-defined echogenic sac wall is absent. In another 9 patients with molar pregnancy managed during the same period, the more typical 'snow-storm' vesicular appearance was present. It was concluded that the anembryonic appearance described should alert the sonologist and clinician to the possible diagnosis of partial hydatitiform mole. The evacuated material from the uterine cavity should be examined morphologically and if possible cytogenetically.

Adult↗
PubMed1983

Sonographic appearances of the partial hydatidiform mole.

A partial hydatidiform mole differs morphologically and cytologically from the complete mole. Correct preoperative diagnosis of the partial mole by ultrasonography is often difficult. Some partial moles have sonographic appearances indistinguishable from those of the common complete moles or missed abortions. The predominant feature in the remainder is the presence of a well-defined gestational sac, either empty or containing inappropriately small fetal echoes, surrounded by a relatively thick rim of placental echoes with intermingling cystic spaces. An echogenic rim around the sac, as is found in missed abortion or blighted ovum, is notably absent. There appeared to be no correlation between these sonographic patterns and the clinical profiles of patients.

Abortion, Missed↗
PubMed1983

Fibreoptic bronchoscopy in the diagnosis of bronchial cancer: comparison of washings, brushings and biopsies in central and peripheral tumours.

Fibreoptic bronchoscopic cytodiagnosis by washings and brushings and histodiagnosis by forceps biopsy were studied in 484 Chinese patients with bronchial carcinoma. When the tumour was bronchoscopically visible, the yields of the three procedures were: washings 76%, brushings 74% and biopsy 82%, giving a total yield of 94%. For peripheral bronchoscopically non-visible tumour, the yields were 52%, 52% and 61% respectively, making a total yield of 86%. Bronchial washings and brushings were important complementary procedures to biopsy and provided the exclusive diagnosis in 12% of the central and 25% of the peripheral tumours. The cytologic cell typing accuracy is 92% for epidermoid carcinoma, 87% for small cell carcinoma, 83% for adenocarcinoma and only 38% for large cell carcinoma. The accuracy of cell-typing of the two bronchial cytodiagnostic methods was comparable in central tumours, but higher with brushings in peripheral tumours.

Adult↗
PubMed1982

Fine needle aspiration in gynaecologic oncology.

One hundred and ten fine needle aspirations were performed on 73 patients with primary and recurrent gynaecological cancers. The sampling sites included superficial and retroperitoneal lymph nodes, soft tissue masses, liver, lungs, abdominal and pelvic masses, parametrium, thyroid and breast nodules. This relatively simple, safe and yet reliable technique can obviate the need for biopsies in most situations, and a more liberal use of aspiration cytology in gynaecological malignancies is advocated.

Biopsy, Needle↗
PubMed1982

Fine-needle aspiration versus drill-needle biopsy of thyroid nodules: a controlled clinical trial.

Percutaneous needle biopsy by two different methods was evaluated in a prospective controlled study of 167 consecutive patients with dominant thyroid nodules. Fine-needle aspiration was superior to high-speed drill-needle biopsy because of its higher diagnostic yield (93.9%). When a sample sufficient for diagnosis was obtained, the accuracy rate for both methods was comparable. Diagnostic errors were due to inadequate samples, difficulties in interpreting hypercellular adenomas, and geographic sampling problems. In the detection of thyroid cancer, neither technique alone appears completely adequate because of occasional false negative errors. The selection of patients for operation should depend on clinical parameters as well as the findings on fine-needle aspiration of thyroid nodules.

Adenocarcinoma↗
PubMed1982

Reading disabilities: the case of Chinese, Japanese, and English.

A common hypothesis has considered apparent differences in the incidence of reading disability in Asian and Western languages to be related to orthographic factors. A reading test was constructed in English, Japanese, and Chinese to assess the validity of this proposal. Large samples of fifth-grade children in Japan, Taiwan, and the United States were given the test and a battery of 10 cognitive tasks. Strong evidence was found that reading disabilities exist among Chinese and Japanese as well as among American children. In discriminating between groups of poor and average readers by means of the cognitive tasks, the combined effects of general information and verbal memory proved to be the most powerful predictors in Japan and Taiwan. General information and coding emerged as the most effective predictors for American children. The results cast doubt upon the crucial significance of orthography as the major factor determining the incidence of reading disabilities across cultures.

Child↗
PubMed1981

The use of bacteria as markers of leukemic lymphocytes and for the isolation of natural killer cells.

Human lymphocyte subpopulations as well as leukemic lymphocytes can be identified and enumerated in blood smears by using bacteria that bind spontaneously to lymphocytes or by using bacteria to which antibodies are chemically coupled. The mechanism of natural binding of bacteria to lymphocytes was shown to involve a lectin on the lymphocyte surface and a carbohydrate on the bacteria. Also, we found that natural killer (NK) cells can be separated by negative selection using monolayers of bacteria. A subpopulation of T cells, identified by their binding of B. globigii, was shown to be suppressors for NK cells.

Bacteria↗
PubMed1981

Non-endocrine carcinoid tumour of the uterine cervix: aspects of diagnosis and treatment. Case report.

A case of primary well-differentiated carcinoid tumour of the uterine cervix in a Chinese woman of 62 years without endocrine symptoms is reported and its clinico-pathological features, ultrastructure and response to radiotherapy discussed. To our knowledge, it is the first of such cases seen in Hong Kong. Clinically, it presented as a polypoid lesion. The initial diagnosis was squamous carcinoma of cervix stage Ib and the patient was treated with radiotherapy. The tumour disappeared after application of first intracavitary irradiation of 4500 mg h. After completion of 9000 mg h, Wertheim hysterectomy followed and no residual tumour was found. Retrospective staining of the pre-irradiation cervical tumour by Grimelius method was positive for argyrophil granules and electron microscopic study demonstrated neurosecretory granules in the cytoplasm and established the diagnosis.

Carcinoid Tumor↗
PubMed1981

Residual trophoblastic disease in association with partial hydatidiform mole.

A 10-year retrospective study was carried out of cases diagnosed as hydatidiform mole at the University of Hong Kong. Strict morphologic criteria established in a previous report were used to study the association of the partial mole syndrome with residual trophoblastic disease. Of the total of 138 cases available, 13 were found to be partial moles, 1 of which was followed by trophoblastic disease that required chemotherapy. This subsequently proved to be an invasive (partial) mole, the first example of its kind to be verified by pathology. The extent of the association between partial mole and subsequent trophoblastic disease and the spectrum of the pathologic lesions actually underlying the latter remain to be determined by further retrospective and prospective studies.

Adult↗
PubMed1981

The temperamental characteristics of Chinese babies.

This paper investigates the usefulness of Carey's Revised Infant Temperament Questionnaire in the Chinese culture and uses the questionnaire to assess the temperamental characteristics of Chinese babies. The revised questionnaire was administered to the mothers of 349 4--8-year-old infants in Taipei, Taiwan. The face validity of the questionnaire was supported within the different context: the distribution of scores was normal, and the mothers had no trouble in answering the questions. While the general pattern of results was similar to those found in Carey's American sample, differences were found, which may be interpreted in terms of response biases, racial differences, or a combination of these 2 factors. The data are analyzed for possible effects of sex and socioeconomic status, and these findings are in turn compared to results of American studies. Observational studies are seen as necessary in the future to understand the nature of cultural differences in temperament. Follow-up studies will examine the different ways a given temperamental characteristic may be responded to by different cultural environments.

Cross-Cultural Comparison↗
PubMed1976

Serial liver biopsy observations in hepatitis B antigen carriers by light and electron microscopy.

Liver morphology and function were restudied after an interval of 1 1/2-2 years in 21 Chinese men with hepatitis B antigen (HBsAg). Antigenemia and mild liver histopathology disappeared in one individual who developed antibody to HBsAg(Anti-HBsAg). 20 subjects who were chronic carriers of HBsAg had mild histological abnormalities which were usually persistent and were more commonly lobular than portal. Particularly striking were focal necrosis, eosinophilic bodies, ground-glass cytoplasmic change, and, by electron microscopy, microtubular structures within cytoplasmic membranous cysternae. Interval development of chronic aggressive hepatitis was observed in only one subject. This study suggests that the great majority of HBsAg carriers have a good prognosis at least over a 1 1/2-2-year period, and that liver biopsy is most indicated in those with persistent liver function abnormalities.

Adult↗
PubMed1975

Endometrial ossification.

Irregular growth of bone was seen in endometrial tissue curetted from a 41-year-old woman, 12 months after an abortion. Bone was present in a second specimen taken later. On hysterectomy 22 months after the abortion, no trace of the abnormal tissue was found. The heterotopia is considered to be due to metaplasia occurring in cells initially concerned in the post-abortion reparative process.

Abortion, Spontaneous↗