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Biomedical subjects

C Holm

Publications and source records attributed to C Holm.

179 records · Page 10Linked to original sources

Orbital septorhaphy for the correction of baggy upper and lower eyelids.

Eyelid bags are the result of relaxation of lid structures like the skin, the orbicularis muscle, and mainly the septum, with subsequent protrusion or pseudo herniation of intraorbital fat contents. The logical treatment of baggy upper and lower eyelids should therefore include repositioning the herniated fat into the orbit and strengthening the attenuated septum in the form of a septorhaphy as a hernia repair. The preservation of orbital fat results in a more youthful appearance. The operative technique of the orbital septorhaphy is demonstrated for the upper and lower eyelid. A prospective series of 60 patients (50 upper and 90 lower blepharoplasties) with a maximum follow-up of 17 months were analyzed. Pleasing results were achieved in 56 patients. A partial recurrence was noted in 3 patients and widening of the palpebral fissure in 1 patient. Orbital septorhaphy for baggy eyelids is a rational, reliable procedure to correct the herniation of orbital fat in the upper and lower eyelids. Tightening of the orbicularis muscle and skin may be added as usual. The procedure is technically simple and without trauma to the orbital contents. The morbidity is minimal, the rate of complications is low, and the results are pleasing and reliable.

Adipose Tissue↗

Toxic shock syndrome in plastic surgery patients: case report and review of the literature.

Toxic shock syndrome (TSS) is a rapidly developing disease, which may be lethal if not recognized and treated early. TSS unrelated to menstruation comprises an increasing proportion of the cases reported to the Centers for Disease Control during recent years, and a review of the literature reveals that TSS has is reported with increasing frequency in plastic surgical patients as well. The majority of reports relates to aesthetic plastic surgical procedures such as rhinoplasty, augmentation mammaplasty liposuction, and chemical peeling, but cases of TSS following reconstructive breast surgery with musculocutaneous flaps have also been reported. A common denominator seems to be that TSS occurs unexpectedly in healthy patients. Nonmenstrual TSS is apparently associated with a higher mortality rate than TSS associated with menstruation. We report on a case of TSS after exchange of silicone implants and resection of a siliconoma in a 59-year-old woman. Details of the case and a review of the literature are presented.

Breast Implantation↗

Eyebrow asymmetry: ways of correction.

Ocassionally a patient asks for correction of his asymmetric eyelids. In many instances, however, a careful analysis reveals that the actual cause is an asymmetry of the eyebrows. Generally, asymmetric eyebrows are due to excessive muscle dynamics (i.e., a hyperkinesia of the frontalis or the depressor supercilii muscles). Therefore, the asymmetry will not be corrected by an asymmetric blepharoplasty, which will instead disclose the preexisting asymmetry, much to the concern of the patient. Management of the asymmetric brow is demanding and requires a preoperative problem-oriented and detailed analysis of the individual patient to achieve satisfactory results. We present 10-years' experience using a problem-specific approach. This included intramuscular botulinum toxin A injection, superselective neurotomy, endoscopic browlift and traditional procedures such as the coronal and direct browlift. Indication, patient selection, results, and complications are discussed.

Adult↗

The relationship between oxygen delivery and oxygen consumption during fluid resuscitation of burn-related shock.

Although burn-related shock resuscitation based on invasive hemodynamic monitoring has been reported at an increased rate, little is known about appropriate hemodynamic end points. Shock resuscitation based on oxygen transport criteria has been widely used for patients with trauma and patients who undergo surgery, and supranormal values of oxygen delivery (DO2) have been reported in association with an improved survival rate. This improved survival rate has been attributed to a shifting of the critical threshold of DO2 to higher values in these patients. In patients with thermal injuries, the effects of the manipulation of hemodynamics to optimize oxygen transport have not been proven. It is still unclear whether these patients exhibit delivery-dependent oxygen consumption (VO2) during the shock phase. The goal of this study was to evaluate the existence of oxygen supply dependency and to determine critical levels of DO2 in patients with burns. In a prospective study that included 16 patients with serious thermal injuries, we studied the effects of volume loading on DO2 and VO2. A transpulmonary double dilution technique was used for hemodynamic monitoring, and resuscitation end points included a normalization of preload and cardiac output parameters within 24 hours of the thermal injury. Fluid loading with crystalloids and colloids, according to our resuscitation protocol, was used to augment cardiac output and DO2. Of the 16 patients with a mean of 46% total body surface area burned (range, 22%-80%), 8 patients survived and 8 patients died. With the use of progressive fluid loading, cardiac index was restored within 24 hours of admission in all of the patients. Successful resuscitation was associated with increased levels of DO2 and VO2 and with declining serum lactate levels. VO2 appeared to be dependent on DO2 during the resuscitation period (r = 0.596), and the correlation was significantly stronger in the patients who survived (r = 0.744) than in the patients who died (r = 0.368; P < .05). A critical threshold of oxygen supply could not be identified. We concluded that increasing DO2 by fluid resuscitation increases VO2 during hypovolemic shock after a severe burn injury.

Adult↗

Portal venous blood flow during and after cholecystectomy.

Eight patients scheduled for cholecystectomy were studied with the aim of defining the pattern of portal venous blood flow in the recovery phase after anaesthesia and abdominal surgery. The continuous thermodilution technique was used for measuring portal flow, via a thermodilution catheter placed in the portal vein after intraoperative umbilico-portal cannulation. Measurement of portal blood flow was begun during surgery and was repeated 2, 4, 6, 8, 12, 24 and 48 hours postoperatively. The flow rate 48 hours after surgery was 977 +/- 182 ml.min-1 (mean +/- SEM), compared with 605 +/- 89 ml.min-1 (p less than 0.05) during cholecystectomy. No significant deviation from the mean intraoperative portal blood flow was found at any of the post-operative measuring points prior to 48 hours. The study's results confirmed the applicability of the thermodilution technique for measuring portal blood flow in awake patients after surgery.

Adult↗