Search PubMed⌕ Search

Biomedical subjects

C Holden

Publications and source records attributed to C Holden.

At least 91 records · Page 5Linked to original sources
PubMed1996

Major vascular injury as a complication of laparoscopic surgery: a report of three cases and review of the literature.

We retrospectively reviewed all 2201 laparoscopic procedures performed at our community teaching hospital in the 3-year period between 1992 and 1995. There were three major vascular injuries, for an incidence of 0.14 per cent. Vessels injured were the left common iliac vein, the right common iliac artery, and the left internal iliac artery. Two of the injuries were believed to involve the 10 mm trocar, whereas the third involved the Veress needle. Two of the injuries were All injuries were successfully repaired primarily. We believe such major vascular injuries can be avoided by strict use of proper techniques of needle and trocar insertion, and by using the open technique to create a pneumoperitoneum in patients with previous abdominal operations. Laparoscopic surgeons should be aware of the potential for injury to major vascular structures and constantly be prepared to identify and treat this potentially life-threatening complication.

Adult↗
PubMed1995

Fluticasone propionate 0.05% cream in the treatment of atopic eczema: a multicentre study comparing once-daily treatment and once-daily vehicle cream application versus twice-daily treatment.

The aim of this study was to compare the efficacy and safety of once-daily with twice-daily application of a 0.05% cream formulation of fluticasone propionate in the treatment of atopic eczema in adults and children. Two hundred and seventy patients with moderate to severe atopic eczema were enrolled in the study, and randomized to receive either once-daily or twice-daily fluticasone propionate 0.05% cream for 4 weeks. Patients randomized to the once-daily group also received the vehicle cream to ensure that the study remained blinded. The clinical response of a preselected target area of affected skin was assessed by investigators at weekly intervals and compared with the baseline. Analysis of the investigators' overall assessment of the response of the target area for both the 'intent-to-treat' population and the per protocol population showed that 79-85% of patients were judged a clinical success. For both populations, there was no statistically significant difference between the response to once-daily and twice-daily active treatment (intent-to-treat; P = 0.35; 95% confidence interval for difference -14.2 to +5.0 percentage points: per protocol; P = 0.42; 95% confidence interval for difference -14.7 to +6.2 percentage points.) The improvement in the signs and symptoms was judged a success in 95-97% of patients. There was an equal reduction in severity scores for disease activity in both groups, and the speed of symptom relief was similar.(ABSTRACT TRUNCATED AT 250 WORDS)

Administration, Topical↗
PubMed1995

Clinical examination compared with anthropometry in evaluating nutritional status.

Clinical assessments of nutritional status in a group of 44 inpatients, made by a panel of experienced childcare specialists, were compared with anthropometric assessments. Assessors were uniformly poor at detecting severe malnutrition and at assessing the nutritional status of infants. Nutritional status cannot be accurately assessed clinically and anthropometry is crucial.

Anthropometry↗
PubMed1993

Anatomic variance in the cholecystic blood supply: a case report.

The cystic artery is known to arise from many possible origins; with the right hepatic artery is the most common. Other origins of the cystic artery include the left hepatic artery, the common hepatic artery, and the superior mesenteric artery. In addition to the variability in origin of the cystic artery, its course can also follow diverse paths, often in close proximity to the common bile duct. This report presents a rare and, to our knowledge, previously unreported deviation of the cystic artery's origin and course that was encountered during cholecystectomy. This rare variant emphasizes the importance of a thorough knowledge of cystic arterial variations that often occur and may be encountered during both open and laparoscopic cholecystectomy.

Aged↗