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Biomedical subjects

C Holdcroft

Publications and source records attributed to C Holdcroft.

27 records · Page 2Linked to original sources
PubMed1989

A comparison of nizatidine with the three other histamine receptor antagonists for duodenal ulcer therapy.

Nizatidine (Axid) is the newest of four histamine receptor antagonists approved by the Food and Drug Administration for treatment of duodenal ulcer and maintenance therapy. It is as effective as the other histamine blockers in healing active duodenal ulcers and in the prevention of relapse. Nizatidine is comparable in price to cimetidine (Tagamet). Nizatidine does not interfere with the hepatic metabolism of other drugs. No significant central nervous system side effects have been reported. It is safe to use in elderly patients or in patients with renal insufficiency. The dosage, however, should be decreased when renal function is impaired.

Duodenal Ulcer↗
PubMed1988

Evaluating involuntary weight loss in older adults.

Involuntary weight loss is a common complaint among patients over 40 years of age. Few studies concerning the etiologies of weight loss, however, have been published. This article reviews two recent studies that address common causes of unintentional weight loss. In these investigations, almost half of the patients claiming significant weight loss had no decrease in weight at all. In 35 percent of patients with true weight loss, no physical source was found after six months of follow-up. Of those in whom a cause of weight loss was discovered, the etiology was usually apparent after a brief history, physical exam and screening laboratory evaluation. Common causes of involuntary weight loss are discussed. Guidelines for evaluation of the patient who complains of weight loss are offered.

Adult↗