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Biomedical subjects

C Hoang

Publications and source records attributed to C Hoang.

70 records · Page 4Linked to original sources
PubMed1983

[Total villous atrophy, mesenteric lymph-node cavitation, splenic atrophy. An unusual form of celiac disease in adults, apropos of a new case].

The authors report a new case concerning the syndrome "total villous atrophy, mesenteric lymph-node cavity formation and splenic atrophy" in a 41 year old woman. This pathologic association is characterized by: a) a clinical and biological malabsorption syndrome; b) proximal small bowel alterations as observed in coeliac disease, with, especially subtotal or total villous atrophy, abnormal enterocytic epithelium, hyperplastic crypts and lymph-plasmacytic infiltrate in the lamina propria; c) lymph node mesenteric cavity formation with an heterogeneous necrotic, sometimes liquefied, substance, without germ or parasite. Rare cortical lymphoid follicles are still persistent; 3) a splenic atrophy. A temporary improvement with gluten-diet (G.F.D.) was followed by a one-year period of total resistance. A treatment including corticotherapy was then successful and since the 14 past months her health remained satisfactory. Clinical, pathological data and the evolution about this patient are compared with those of the six published cases. The aetiology of this syndrome only observed in adults at the present time is unknown; the fact that patient's child presents with a coeliac disease, allows to authenticate, for the first time, this syndrome as a special form of adult coeliac disease.

Adult↗
PubMed1982

[Visceral histologic lesions of lethal acute colchicine poisoning. Apropos of 12 cases].

The authors reported histological characteristics (on post-mortem examination) of 12 cases of lethal acute colchicine intoxication and compare these results with the 5 previous anatomical studies of such cases in the literature. Abnormal mitosis (stathmocinesis, "caryomerie", caryorrhexis and mitonecrosis) are constant and essentially seen in the bone marrow and digestive mucosae, especially in oesophagus which squamous epithelium is more resistant to autolysis than others digestive mucosae. Biological or histological symptoms or lesions of intravascular diffuse coagulation are present 7 cases but both biological and histological manifestations in only one case. Hematological disorders are constant when more than 0.5 mg/kg (of corporeal weight) of colchicine has been ingested. Granulocytic elements are most affected both by hypoplasia (essentially in the first four days) and maturation troubles. A microvacuolar non systematized and diffuse liver fatty change is found in 10 cases, probably related to alteration of lipoproteins synthesis and secretion by hepatocytes. Interstitial myocardial oedema is a constant feature; in addition true interstitial myocarditis (with infiltration by polymorphs) is seen in two cases. These cardiac lesions may be related to the cardiogenic shock which is often observed in these patients.

Acute Disease↗
PubMedDate not supplied

Rectal malacoplakia in renal transplantation: MR features.

This report describes the CT and MRI features of rectal malacoplakia in a renal transplant recipient. The lesion appeared strongly hyperdense (105 HU) on unenhanced CT and demonstrated hypointense signal on T1- and T2-weighted MR imaging with slight homogeneous enhancement after gadolinium injection. These characteristics distinguish this lesion from other more common neoplastic, inflammatory rectal lesions that are typically isointense on T1-weighted imaging and enhance variably after gadolinium injection. Characteristic intracytoplasmic siderocalcific spherules in malacoplakia can produce suggestive features on unenhanced CT and MRI.

Colonic Diseases↗
PubMedDate not supplied

[Inverse polypoid hamartoma of the rectum with colonic extension of the lesions and deep cystic colitis with rectal involvement. Apropos of an anatomo-clinical case report].

The authors report the case of a 38 year old man, presenting with an inverted polypoid hamartoma (IPH) of the rectum, associated with similar colonic localizations and they show the resemblance of these lesions to the colitis cystica profunda (CCP) with involvement of the entire large bowel and eventually the rectum. In fact, moreover, the symptoms, the digital rectal examination and the endoscopic, radiological and pathological data are similar but, in the reported cases, the IPH always included at least one rectal localization whereas the CCP might not show rectal lesion. Advanced lesions of rectal IPH may be confused, by endoscopy and pathology with adenomas or adenocarcinomas. Consequently it is essential to perform large and deep biopsies for histological diagnosis. The IPH and the CCP are benign diseases but "recurrence" may be observed in case of incomplete removal. The removal has to be adequate but not mutilating, either by surgery or by laser endoscopic photoablation. The choice of the procedure will depend upon the size of the lesion.

Adult↗
PubMedDate not supplied

Comparison of cytologic examination of smears and histologic examination of tissue cores obtained by fine needle aspiration biopsy of the liver.

Biopsies of 30 consecutive suspected liver cancers were performed with 19-gauge fine needles having circumferentially bevelled tips that produced tiny tissue cores suitable for histologic study. The histologic results were compared with the cytologic results on aspirates obtained at the same time with 22-gauge Chiba needles. While cytologic examination of the aspiration smears produced better results than did histologic study of the tiny tissue cores, an improved overall accuracy of 86% was achieved with the combined cytologic and histologic results. The FNA core biopsy technique did not increase the complication rate.

Biopsy, Needle↗