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Biomedical subjects

C Hessler

Publications and source records attributed to C Hessler.

At least 37 records · Page 2Linked to original sources
PubMed1989

[Breast cancer before 36 years of age].

Breast cancer in young women is a dreaded disease of bad prognosis, classically worse than for older women. A local study was undertaken in Lausanne to evaluate this notion. 94 cases aged less than 36 years were collected over 15 years, the incidence being 9 new cases per years per 100,000 under-36 women. 76% of the tumors were discovered accidentally by the patient, 24% by a physician during a routine breast examination. Delays from first symptom to histologic diagnosis were short, averaging 19 weeks. 80 mammographies were performed on the 94 cases, of whom 50 positives for a cancer, and 29 negative or doubtful. 22 of these negative 29 were reevaluated, 7 being positive for a tumor and 15 negative, showing either a benign mass or no lesion at all. 6 of the 7 positives were misdiagnosed in easy-to-read breasts, the false interpretation being chiefly caused by the young age of the patients. Pathologically, the rate of invasive ductal carcinoma was very high at 91.4%, which is the highest in the literature, and much higher than for older women in Lausanne (68%). Survival was 84% at two years, 63% at five years and 46% at 10 years, all deaths due to breast cancer. Those rates are better, globally and stage by stage, than for older women or than other reports on young women. We conclude that breast cancer in young women has a better prognosis than formerly thought.

Adult↗
PubMed1988

The potential aggressiveness of sinus osteomas. A report of two cases.

The fronto-ethmoidal osteoma is a relatively rare radiological finding and its growth potential, as well as the complications it may lead to, are often underestimated. Osteomas are a frequent cause of mucoceles and sinusitis due to blockage of the nasal ducts but can also present with more dramatic signs such as orbital or intracranial invasion. This knowledge must draw our attention to the need for follow-up of these tumors, whose growth apparently continues after puberty, especially when they are of the spongy type.

Adult↗
PubMed1988

[Screening for breast cancer].

On the "why", "whom" and "how" of breast screening for carcinoma, the following answers can be provided: Why? As there is no primary prevention, secondary prevention by early diagnosis is the only way to reduce breast cancer mortality. On the other hand, breast cancers discovered by screening can be conservatively treated more often than when they become symptomatic; this is especially important in young patients. For whom? Every woman over the age of 35-40 should be accepted for breast cancer screening. In countries such as Switzerland it is unthinkable to impose screening or even to send personal invitations for screening to the population. Only repeated information through newspapers, TV and conferences will induce women to come for screening. The costs would be paid for by the patient, as medical insurances do not cover this type of preventive medicine. How? Only screening through mammography with or without breast palpation, performed by paramedical personnel, can be considered, because of the cost. It should be done outside the senologic consultation setup for symptomatic patients where a doctor is in charge of the clinical consultation. As Doctor Van der Linde said at the end of his talk at the last Convention of the Swiss Senology Society in Lausanne, pilot projects for breast screening in Switzerland should be started. The Swiss Cancer Society has lately created a commission for early detection of breast cancer to study ways of launching a project.

Adult↗
PubMed1986

[Large breasts, small breasts; which mammographic technic?].

The variation of dose and image quality parameters in the voltage range 25...33 kV have been studied on 3 mammographic phantoms simulating thin, average and thick breasts respectively. The global image quality has been objectively evaluated by an image quality index. The average glandular dose has been chosen as relevant indicator of risk. The study shows that the surface dose and the midplane dose are not suitable indicators of risk if the breast thickness is variable. For all phantoms, the deterioration of image quality with voltage increase was found to be relatively less important than the decrease of the average glandular dose. Consequently, the following optimum voltages are proposed: 28-29 kV for thin breasts, 29-30 kV for average breasts and 33-35 kV for thick ones. The study showed that breast thickness variation is not suitably compensated by the automatic exposure devices currently available.

Breast↗
PubMed1985

Objective assessment of mammography systems. Part I: Method.

The authors have developed an experimental method for simultaneous determination of dose and image parameters in mammography. A global and objective quality concept, the image quality index, is proposed and its reliability demonstrated by tests of reproducibility. Objective quality tests and subjective evaluation by radiologists showed good correlation.

Evaluation Studies as Topic↗
PubMed1985

Objective assessment of mammography systems. Part II: Implementation.

A quality control program for mammography units was carried out, based on objective tests of image quality and dose. Results are reported for 31 units, including correlation between various parameters. Satisfactory results were obtained in the case of 21 installations; for the other 10, comparison between measured quality parameters and those of the reference system suggested ways in which quality might be improved.

Female↗
PubMed1982

[Gynecomastia. Radiological and pharmacological aspects].

Though frequently unilateral on clinical examination, mammography often reveals the presence of a small impalpable gynecomastia in the contralateral breast. The left breast appears to be the one usually involved, both clinically and radiologically. Gynecomastia is usually iatrogenic in nature, mainly as a result of cardiac stimulants or diuretics, but on rare occasions arises from severe unsuspected organic lesions in the testes, liver, or adrenals, or from endocrine disequilibrium.

Adult↗
PubMed1981

[Subclinical varicocele: detection using Doppler and thermography].

We think that we must find out a varicocele in every case of oligospermia, asthenospermia and teratospermia, particularly with spindle-shaped spermatozoa. If the clinical examination remains negative, it is necessary to provoke a backflow at the Doppler by carrying out a Valsalva's maneuver. If the obtained result is positive, we must then make a high ligature on the left vena spermatica. It seems that the bursae thermography has a prognostic value on the spermogramme's evolution following a subclinical varicocele cure.

Humans↗
PubMed1978

Hamartoma of the breast: diagnostic observation of 16 cases.

Of 10,000 mammographies done over a 9-year period, 16 cases of hamartoma of the breast were diagnosed. The entity is a well delimited mass composed of dysplastic-appearing mammary tissue admixed to fat. It can be readily recognized and should not be confused with fibroadenoma or mammary dysplasia. The accuracy with which it can be diagnosed by mammography makes possible the avoidance of surgical excision in selected patients.

Adult↗
PubMed1977

[Diagnostic procedures in the evaluation of malignancy degree in breast cancer. Radiological view point].

The value of mammography and thermography for evaluation of breast cancer malignancy is reviewed. The only radiologic finding that changes the prognosis is peritumoral edema, either localized or involving the whole breast; when present, this edema has unfavourable implications for prognosis. Thermography, on the other hand, provides a much better idea of prognosis when the tumor is palpable. In this case the prognosis is influenced much more by the degree of hyperthermia than by the clinical size of the lesion.

Breast Neoplasms↗