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Biomedical subjects

C Heiden

Publications and source records attributed to C Heiden.

9 recordsLinked to original sources

[Hyperbaric oxygenation in early treatment of sudden deafness].

BACKGROUND: The treatment of sudden deafness with hyperbaric oxygenation (HBO) is a new method, which is a routine application in some German centers and subject to contraindications can be assessed as relatively reliable. PATIENTS AND METHODS: In a retrospective study, data were analyzed from 49 patients who had received primary HBO therapy because of sudden deafness (up to 3 weeks old). In comparison to the standard infusion therapy according to Michel, the primary HBO therapy led to inferior results (no change in hearing: right ear 63.88%, left ear 60.98%; improvement in hearing: right ear 22.49%, left ear 21.71%; decrease in hearing: right ear 13.64%, left ear 17.32%). RESULTS: Considering the spontaneous remission of sudden deafness, neither the results of the infusion therapy nor those of the hyperbaric oxygenation surpass the rate of complete spontaneous remission. On the basis of our research, primary treatment of "fresh" sudden deafness with hyperbaric oxygenation cannot be recommended. CONCLUSIONS: The question remains open whether HBO as a secondary treatment for sudden deafness leads to improvements for the patient after unsuccessful standard therapy.

Adult↗

[Earache and functional disorders of the cervical spine].

The importance of the cervical spine in routine ENT practice is discussed, using the example of otalgia due to disorders of the cervical vertebra: Evaluation and follow-ups of 13,000 patients showed that 6% had diseases caused by the cervical spine. Frequency, pathophysiology and treatment results of cervicogenic otalgia are presented. The principles of adequate functional diagnostics and therapy of cervical spine disorders are explained.

Atlanto-Axial Joint↗

Magnetoencephalography using high temperature rf SQUIDs.

We have developed high-critical-temperature radio-frequency Super conducting QUantum Interference Devices (SQUIDs) with step-edge grain-boundary Josephson junctions and large flux focusers. These planar devices were fabricated from epitaxial YBa2Cu3O7 films and operated in the magnetometer and first-order gradiometer configurations while immersed in liquid nitrogen. At the temperature of 77K, we have attained a magnetic field resolution for the magnetometer better than 200 fT/Hz1/2 down to less than 1 Hz, i.e., over the low signal frequency range important for medical diagnostics. The results to date show a high promise for biomagnetic diagnostics. For the first time, we recorded the evoked responses from human brains using a high-temperature magnetometer and a first-order electronic gradiometer channel simultaneously. These results were obtained in a magnetically shielded room. An improvement in the magnetic field resolution by another order of magnitude is possible and probable.

Acoustic Stimulation↗

High temperature RF SQUIDs for biomedical applications.

We have been investigating the feasibility of radio-frequency RF, low-noise superconducting quantum interference device (SQUID) magnetometers and gradiometers operating in liquid nitrogen at 77 K. Using flux-focusing structures fabricated from epitaxial YBa2Cu3O7-chi films, we have attained a magnetic field resolution for a magnetometer of better than 200 fT Hz-1/2 at less than 1 Hz, i.e. over the low signal-frequency range important for biomedical diagnostics. At 77 K, this magnetometer recorded diagnostically useful heart signals, voluntary eye-blink signals, and also the first evoked response of a human brain. These and similar results were obtained in a magnetically shielded room. We were also able to record heart signals in the absence of any shielding when using a first-order gradiometer. An improvement in the magnetic field resolution of our magnetometers and gradiometers by, at least, another order of magnitude is possible and probable.

Electric Conductivity↗

SQUID and SQUID system developments for biomagnetic applications.

This report describes developments carried out at the author's institution concerning SQUIDs and SQUID systems, based on both conventional niobium technology and high-Tc superconductors. The developments are aimed at increasing the acceptance of SQUID systems by the user from the technical point of view. Reliability and ease of operation are improved by simpler electronics, faster response and reduced number of leads in multichannel systems, and higher operating temperature. The developments include a DC SQUID with FM read-out, resulting in the most compact SQUID electronics so far, a planar microwave biased RF SQUID with very high slew rate, and efforts to create reliable SQUIDs with sufficient sensitivity for biomagnetic applications that are cooled by liquid nitrogen.

Equipment Design↗

[Side-effects and complications following suspension laryngoscopy].

The following report deals with the frequency of side-effects following suspension laryngoscopy and ways to avoid them, based on the evaluation of 800 cases. As there was only a low rate of complications established (4,5 per cent) which is mainly caused by tooth damages and intubation-lesions, the preoperative information may be limited to those two points.

Cicatrix↗