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Biomedical subjects

C Hadnagy

Publications and source records attributed to C Hadnagy.

At least 37 records · Page 2Linked to original sources
PubMed1977

[Geophagia sideropenica].

The authors describe two cases of geophagia (45 years old mother and her 25 years old daughter). Both suffered from an anaemia of medium degree only (case 1: 3.77 million of erythrocytes, Hb 8.5 g%; case 2: 3.34 million of erythrocytes, Hb 10 g%), there was a serious iron deficiency (46 and 35 microgram % respectively of serum iron). Both were blood donors, the mother 7 times and the daughter 31 times. In both cases the iron deficiency existed before geophagia. The desire for eating argillacecous earth already disappeared after the application of some ampules of Ferrlecit injected intravenously, even before the values of the serum iron and the number of erythrocytes had changed. The number of erythrocytes, the Hb value and that of haematocrit as well as the values of the serum iron normalized completely. EEG changes were observed in both cases, which could be influenced by the ferrotherapy. The authors recommend the serum iron estimation in all blood donors as well as the introduction of their routine treatment with iron preparations.

Adult↗
PubMed1977

[Hepatogenic polyglobulinemias and polycythemias].

The authors distinguish three kinds of hepatogenous polyglobulia: Polycythaemia caused by Budd-Chiari syndrome, polycythaemia caused by a Mosse syndrome (cirrhosis without liver venous thrombosis) and polyglobulia caused by liver tumours. In all three cases the same mechanism is likely to induce polycythaemia or polyglobulia respectively. In addition to the three cases of the Mosse syndrome published in 1966, the present paper deals with three cases of Budd-Chiari syndrome. Twice the Budd-Chiari syndrome was followed by a polycythaemia, once a Budd-Chiari syndrome was developed in the course of a polycythaemia vera.

Adult↗
PubMed1977

[Sideroblast content of the bone marrow at the end of pregnancy or 1st days of puerperium, respectively].

We examine in the last month of the pregnancy, resp. in the first week of their lactation period, the frequency of sideroblasts in the bone marrow of 265 pregnant women without iron or folate supplements. In 69,4% of the cases the frequency of sideroblasts was not more than 10% (in 34,7% of the cases sideroblasts were absent). After previously parenteral administered 0,6 to 0,9 g iron (10 to 15 Amp. Ferrlecit), iron was present in the marrow. In all examined megaloblastic anaemia of pregnancy cases and in 91% of praemegaloblastic cases, the marrow contained sideroblasts. If the number of sideroblasts proved increased (greater than 25%) the serum folate level was decreased (less than 4 ng/ml).

Bone Marrow↗
PubMed1975

[Association of chronic myelosis and cancer].

During the period between 1948-1963 a total of 3,200 tumor patients were treated in the First and Second Medical Clinics of Tg.-Mures. In these tumor patients as well as the skin cancer patients who were treated with radiotherapy the authors found in 1.5% of the patients a leukocytosis of more than 20,000. In the last ten years (1964-1974), however, in the Second Medical Clinic only, 5% of 516 tumor patients showed a leukocytosis exceeding 20,000. In the first group of patients (3,200 cases) 0.03% showed more than 50,000 leukocytes, in the other group of 516 patients 0.2% showed more than 50,000 leukocytes. These values point towards a leukemoid reaction. A shift to the left to the myelocytes or beyond in the blood picture was found in the Second Medical Clinic in 10% of patients with carcinoma during the year of 1974. In 6% of the cases erythroblasts in the peripheral blood were seen, too. This deviation occurred often independent of the total number of leukocytes and was of a temporary nature. During the same time (1949-1974) 128 patients with chronic myeloid leukemia were treated in both departments as in-patients. 6 cases (i.e., 4.6%) had a chronic myelosis simultaneous with carcinoma, in one case together with an osteosarcoma. The diagnosis was confirmed in all cases by autopsy.

Autopsy↗
PubMed1975

[4 cases of congenital afibrinogenemia (author's transl)].

Report on 4 members of one family with afibrinogenemia. 2 of them died of cerebral hemorrhage at the age of 10. The 2 surviving children are 8 and 10 years old. Plasmafibrinogen was determined in 69 members of the family. Only in the parents of 2 patients was plasmafibrinogen found to be slinghtly reduced. But in other members of the family fibrinogen was low. In our cases, too, the ADP induced aggregation of thrombocytes in plasma obtained with citrate was weaker than normal.

Adenosine Diphosphate↗