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Biomedical subjects

C H Siar

Publications and source records attributed to C H Siar.

At least 55 records · Page 3Linked to original sources
PubMed1990

Combined granular cell ameloblastoma and plexiform granular cell odontogenic tumour.

Granular cell ameloblastomas are uncommon lesions accounting for about 3-5% of all histologic subtypes of ameloblastoma. The plexiform granular cell odontogenic tumour, on the other hand, is a newly described lesion characterised by a monophasic plexiform pattern of granular cells. This article reports a tumour found occurring in the left mandible of a 67-year-old Indian male which histologically showed features of both the aforementioned lesions.

Aged↗
PubMed1989

High-grade malignant mucoepidermoid tumour of tongue. A case report.

Mucoepidermoid tumours of the minor salivary glands of the tongue are rarely encountered. A case of a high-grade malignant type is reported here. Merits of subdivision of the mucoepidermoid tumour on the basis of its malignant potential are outlined, and variations of histological presentation of the present tumour at its primary and nodal sites are discussed.

Carcinoma↗
PubMed1989

An aggressive anaplastic squamous cell carcinoma of the floor of the mouth in a young patient: report of a case.

Anaplastic squamous cell carcinoma occurring in the young patient is an uncommon disease. Only a few cases have been reported in the literature in the last 30 years. This paper presents the rare case of a young male presenting with an aggressive squamous cell carcinoma of the floor of the mouth. At the time of his admission, the tumor had already spread to the cervical and supraclavicular nodes bilaterally. The patient died before completing the course of radiotherapy. The case is discussed with special emphasis on the differential diagnosis, etiology and prognosis of the lesion.

Adolescent↗
PubMed1989

Peripheral complex odontome with ghost cell epithelium. A case report.

Odontomes are malformations of dental tissues found commonly within jaw-bones and to a lesser extent in the soft tissue. A case of peripheral complex odontome exhibiting ghost cell epithelium is presented here. The significance of the ghost cells and origin of the odontome are briefly commented upon.

Child↗
PubMed1988

Orthokeratinised odontogenic keratocysts in Malaysians.

The records of the Division of Stomatology, Institute for Medical Research, Kuala Lumpur, Malaysia, were reviewed for the incidence of odontogenic keratocysts of the orthokeratinised variety, during the 20-year-period, 1967 to 1986. Nine cases were found. The clinical, histological and radiological features of these cases are reported. Many features were similar to previous reports of this entity but a peak incidence in the second decade of life, an almost even distribution in the maxilla and mandible, and a distinct predilection for the Chinese were observed. It is suggested that these features may be peculiar to Malaysians.

Adolescent↗
PubMed1988

Histological variation of the lining epithelium of the calcifying odontogenic cyst. A light microscopic study.

The lining epithelium of thirty cases of calcifying odontogenic cysts (COC) was studied light microscopically. Results show two distinct types: 1. the classical highly-differentiated lining epithelium characterised by a basal layer of columnar cells with nuclear polarisation supporting suprabasally several layers of stellate reticulum-like cells and containing variable amount of ghost cells present in all the cases and a necessary criteria for the diagnosis of COC; 2. the undifferentiated lining epithelium which is of 2-3 cells to 5-8 cells thick, non-, para- or orthokeratinised and resembled reduced enamel epithelium. This is seen in some cases in some parts of the cystic lining. Variations within the highly-differentiated epithelium include spindle-cell change, epithelial pearl formation and ghost cell dominant type. In the present series, ten cases were associated with odontome formation, three with melanin pigment and one with clear cells. The study supports the concept that COC are lesions of odontogenic origin that may arise as primary lesions from the remains of the dental epithelium or secondarily from the lining epithelium of pre-existing lesions.

Adolescent↗
PubMed1987

Mucoepidermoid carcinoma with calcifications.

An unusual case of mucoepidermoid carcinoma with ductal and intracystic calcification is described. The nature of these calcareous masses and the differential diagnosis of this lesion are discussed.

Calcinosis↗
PubMed1987

Squamous cell carcinoma in an orthokeratinised odontogenic keratocyst.

Clinicopathological differences between the typical parakeratinised odontogenic keratocyst (OKC) and the orthokeratinised variant are outlined. A case conforming to the histological criteria of an orthokeratinised OKC occurring in association with a squamous cell carcinoma is described and possible relationships between the two entities discussed.

Adult↗
PubMed1987

Residual cyst: an incidental finding during alveolectomy.

A case of a residual cyst with hyaline bodies from the 26 region discovered fortuitously during alveolectomy is described. The importance of preliminary radiographic evaluation is emphasised. Differential diagnosis from the unicystic ameloblastoma is discussed.

Aged↗
PubMed1986

Quantitative histological analysis of the human coronal dentine in dentinogenesis imperfecta types I and II.

The coronal dentine of 3 teeth from dentinogenesis imperfecta (DI) type I, 9 teeth from DI type II and 4 controls were examined by a quantitative histological technique. In each case, two representative demineralized sections, one stained in H + E and the other in Schmorl's picrothionin were used. The relative amount of dentinal tubule, atubular dentine and canals/clefts were assessed using the point-counting method. Three basic patterns of distribution of tubules were observed. Pattern 1 formed the largest group and showed a gradual decrease in tubule count from enamel-dentine junction (EDJ) pulpwards, pattern 2 was characterized by a drop in tubule count approximately midway between EDJ and pulpal border, and pattern 3 exhibited a gradual increase in tubule score as the pulp was approached. At the 5 per cent level, both patterns 1 and 2 were found to be statistically significant. Pattern 3 was statistically insignificant for the test specimens and highly significant for the controls. The variation in the distribution of the tubules in coronal dentine in this study indirectly supports the concept of abnormal dentinogenesis in DI attributable to a diminution or lack of normal functional odontoblasts.

Adolescent↗