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Biomedical subjects

C H Millikan

Publications and source records attributed to C H Millikan.

31 records · Page 2Linked to original sources
PubMedDate not supplied

Temporal profile (clinical course) of acute vertebrobasilar system cerebral infarction.

Records of 37 consecutive patients with acute brain infarction from vertebrobasilar artery disease, admitted to the cerebrovascular hospital service within 36 hours of the onset of symptoms, were studied to define the temporal profile of clinical events during the first week of illness. A stable course with unchanged neurologic deficit was found in 11% (4 patients). Progressive improvement in symptoms occurred in 35% (13 patients). Progressive disability occurred in 43% (16 patients). A remitting-relapsing course was noted in 11% (4 patients). In these latter 2 groups, stabilization of the clinical course occurred in the majority with 48 hours after the initial symptom; however, definite changes continued to develop up to 96 hours in a significant number of patients. Mortality at the conclusion of the first week was 27% for the entire group. This was 2.5 times greater than the 10.6% previously reported for a group of 179 patients with acute brain infarction due to carotid system disease who were concomitantly studied.

Anticoagulants↗
PubMedDate not supplied

Clinical phenomena and their correlation to angiographic findings in cerebrovascular disease.

Seventy-one patients who had cerebral angiography because of clinical evidence of focal ischemic cerebrovascular disease were studied. Seventy-seven per cent of these patients had an arterial lesion in the distribution appropriate to the symptoms. However, the degree of dissemination of the atherosclerotic lesions, lesion morphology and severity of stenosis could not be predicted from the clinical manifestations. The presence of atherosclerotic cerebrovascular disease can usually be predicted by analysis of the symptoms and signs, but the nature and extent of the lesions can only be determined using cerebral angiography.

Adult↗
PubMedDate not supplied

Temporal profile (clinical course) of acute carotid system cerebral infarction.

The records of 179 consecutive patients with acute carotid system cerebral infarction were studied to describe the temporal profile of the clinical events during the first week of the illness. Only those patients admitted to the cerebrovascular hospital service within 36 hours of the onset of the first symptom were included. The neurological status of 39% was stable (unchanged) at the end of seven days; 35% of the patients gradually improved. Nineteen percent had a progressing neurological deficit from the onset which stabilized within 48 hours of onset. Six patients (3%) had a remitting-relapsing course during the first 36 hours. Eight patients (4%) had a significant late worsening, after 48 hours of stable or improving course. Mortality was 11% for the entire group. However, a high risk of death group was identified - the mortality was 41% for those patients who had any degree of decreased level of consciousness and hemiplegia at the time of admission.

Acute Disease↗