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Biomedical subjects

C H Miller

Publications and source records attributed to C H Miller.

At least 235 records · Page 13Linked to original sources
PubMed1968

Cucumber sex expression modified by 2-chloroethanephosphonic acid.

Application of 2-chloroethanephosphonic acid (120 to 240 parts per million) to monoecious cucumber plants when the first true leaf was 2 centimeters in diameter has resulted in as many as 19 continuous pistillate nodes. Control of the flowering habit simplifies the production of hybrid seed and offers the possibility of enhancing cucumber yields.

Ethyl Chloride↗
PubMed1966

Cleavage of S-ribosyl-L-homocysteine by extracts from Escherichia coli.

Duerre, John A. (University of North Dakota, Grand Forks), and Chris H. Miller. Cleavage of S-ribosyl-l-homocysteine by extracts from Escherichia coli. J. Bacteriol. 91:1210-1217. 1966.-Cell-free extracts prepared from Escherichia coli catalyze the cleavage of the thioether linkage of S-ribosylhomocysteine. One of the products has been identified as homocysteine by paper chromatography of the N-ethyl-maleimide derivative and can be measured directly in reaction mixtures by sulfhydryl reagents. The other compound has been tentatively identified as ribose by column chromatography. Free sulfhydryl groups were also detected with use of S-adenosylhomocysteine as substrate; however, enzymatic cleavage of the glycosidic linkage of this compound appears to be required prior to cleavage of the thioether linkage. Homocysteine formed from either substrate could be converted readily to methionine, provided the necessary cofactors were added. Some of the properties of the ribosylhomocysteinase are discussed.

Chromatography, Paper↗
PubMedDate not supplied

Factor VIII-related antigen pre-peak on crossed immunoelectrophoresis: a non-random phenomenon.

The incidence of a "pre-peak" over the well on crossed immunoelectrophoresis of factor VIII-related antigen (VIIIR:Ag) was found to be not significantly different in groups of hemophilia carriers and non-carrier women. Only 10% of hemophiliacs more than three days post-transfusion exhibited the feature. Upon transfusion 5 out of 6 hemophiliacs showed a transient appearance of the pre-peak. It was also present during pregnancy in 6 of 8 normal women, 2 hemophilia carriers and two von Willebrand's patients. The pre-peak pattern was quite reproducible both in the same sample tested on different days and in different samples from the same subject. The pre-peak material shows a line of treatment of plasma and by cryoprecipitation.

Antigens↗