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Biomedical subjects

C H Mann

Publications and source records attributed to C H Mann.

22 records · Page 2Linked to original sources
PubMed1977

Thyroid abscess in a 3 1/2-year-old child.

Thyroid abscess is a rare occurrence; there have been only six reported cases in children in the past 20 years and none of these in the otorhinolaryngologic literature. The presentation of suppurative thyroiditis in the 3 1/2-year-old child described here is somewhat atypical, with a rather insidious onset of swelling in the neck. The white blood cell count was elevated; thyroid function, however, was normal. The child also had an abnormal thyroid scan. Rapid improvement ensued with incision and drainage and appropriate antibiotic therapy. A brief discussion and review of the literature is provided regarding manifestations of previously reported cases. The recognition of this entity is important in order to differentiate from other fascial abscesses of the head and neck.

Abscess↗
PubMedDate not supplied

The value of tests of cure following cervical chlamydial infection.

Test of cure (TOC) was performed 2, 4 and 6 weeks after treatment for cervical chlamydia infection with 10-14 days of Deteclo one tablet twice daily, erythromycin 500 mg twice daily or doxycycline 100 mg twice daily. Testing was by chlamydia culture and IDEIA (DAKO diagnostics Ltd). Discrepant results were subsequently checked by immunofluorescence (Syva MicroTrak) of both sets of left over transport media. Two hundred and three patients attended on at least one occasion; 189, 146 and 107 at 2, 4 and 6 weeks respectively. Of these 127, 70 and 34, respectively, denied sexual intercourse or had consistently used condoms. Fourteen were positive over the study period by either or both methods of detection. Of 8 culture positive results 3 were negative by IDEIA. Two of these had elementary bodies (EBs) on immunofluorescence of both sets of saved transport media. One had EBs on immunofluorescence of the saved culture transport medium only. None of the 6 IDEIA positive, culture negative patients had immunofluorescent EBs in the IDEIA transport media although one had EBs in the saved culture transport medium. One IDEIA suspicious, culture negative patient had EBs in both sets of saved transport media. There was no significant difference in the rate of chlamydia detection from patients admitting to or denying unprotected intercourse. TOC has a low yield in cases of cervical chlamydial infection when there has been careful contact tracing and treatment has been completed. If TOC is performed culture should be used if available and where antigen detection methods are used confirmation should be sought for any positive results.

Chlamydia Infections↗