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Biomedical subjects

C Guinda Sevillano

Publications and source records attributed to C Guinda Sevillano.

At least 19 recordsLinked to original sources
PubMed2000

[Clinical usefulness of free PSA/total PSA ratio in the early diagnosis of prostatic cancer].

OBJECTIVES: To determine the clinical utility of free/total PSA ratio and PSA density in the early diagnosis of prostate cancer (patients with serum PSA between 4 and 10 ng/ml) and to determine the differences, if any, in the free/total PSA ratio in patients with cancer and those with benign prostatic hyperplasia (BPH). METHODS: A prospective and descriptive study was conducted on 61 patients with low grade obstructive symptoms and total serum PSA between 4 and 10 ng/ml (group 1), and 42 patients who underwent prostate surgery and had an anatomopathologically confirmed diagnosis of BPH (group 2). Free and total PSA were determined, as well as prostate volume by transrectal US, in all cases. Prostate biopsy was performed in all patients with a total PSA value between 4-10 ng/ml. The sensitivity, specificity, positive and negative prognostic values of free/total PSA ratio and PSA density were analyzed. RESULTS: The mean age of the patients in group 1 was 67.7 years and 68.3 years in group 2. The mean prostate volume by US was 55.2 and 47.1, respectively (n.s.). The mean total PSA was 6.39 ng/ml for group 1 and 5.73 ng/ml for group 2 (n.s.). No significant difference was found between the mean free PSA values of both groups. However, the free/total PSA ratio and PSA density were significantly different (p < 0.000). In group 1 (total PSA 4-10 ng/ml), prostate biopsy was positive in 32.8% of the patients. In this group of patients, there were no significant differences in the parameters analyzed. Application of different cutoffs for both tests showed a higher clinical utility for the 0.24-0.30 range. CONCLUSIONS: At similar mean prostate volume and mean total PSA, significant differences were found in the free/total PSA ratio and PSA density of patients submitted to surgery for BPH and those with a total PSA value of 4-10 ng/ml. However, these results were not observed when patients with PSA of 4-10 ng/ml were analyzed for presence or absence of evidence of malignancy in the prostate biopsy.

Aged↗
PubMed1998

[Retroperitoneal germinal tumor: extragonadal or burned out phenomenon of testicular primary? Presentation of a clinical case].

Clinical record case of a retroperitoneal seminoma with "burned-out" phenomenon in the testicular primary, in a 38 year old male with no background of interest who consults for a picture of left nephritic colic. The ipsilateral testis study detects a fibrotic area with hyalinosis and hemosiderin deposits, although there are no tumoral debris, compatible with the "burned-out" phenomenon. Management is through surgery plus a chemotherapy protocol. Discussion of the diagnostic algorithm of retroperitoneal tumours and the literature on extragonadal germinal tumours.

Adult↗
PubMed1995

[The role of video voiding cystourethral sonography in the study of the urethrovesical anastomosis following radical prostatectomy].

OBJECTIVE: The sonographic anatomy of the urethrovesical anastomosis in patients submitted to radical prostatectomy is described herein. METHOD: Video sonographic voiding cystourethrography was performed using a 7.5 MHz linear-array transrectal probe. RESULTS: The longitudinal ultrasound scans of the urethrovesical anastomosis during the different phases of micturition are shown. CONCLUSION: Video sonographic voiding cystourethrography is useful in the evaluation of the urethrovesical anastomosis after radical prostatectomy, at rest and during micturition. It also permits detecting any postoperative complication as hematoma, abscess or early recurrence.

Anastomosis, Surgical↗
PubMed1995

[Brucellar orchitis. Report of a series of 16 cases].

A retrospective study of orchiepididymitis, diagnosed and admitted to our Unit over the 1989-94 period was conducted. there were 125 orchiepididymitis, of which 16 (12.8%) had a brucellar etiology, and three had simultaneously become abscessified (18.75%). Considering that our working area is located within an endemic region, and even more, our province has the country's highest incidence rate (112.8/100000 inh.), this prompted us to study the conditions' morbidity in the testicular location, while we make a superficial revision of this disease. Brucellar orchitis is a diagnostic option to be taken into account in endemic regions, and the clinical picture associated to the orchiepididymal process should make us suspect its diagnosis and trigger follow-up of these patients.

Adolescent↗
PubMed1995

[Abscessed brucellar prostatitis. An infrequent location].

Explanation of one case of abscessified brucellar prostatitis in a 44-year old patient. The emphasis is placed on the high incidence of brucellosis in the province of Soria and the rarity of the prostatic location of this condition. Also, a revision is made of the diagnostic methodology and current therapeutical approaches. The crucial role of the endocavitary ultrasound techniques both for diagnosis as well as treatment and case follow-up is highlighted.

Abscess↗
PubMed1994

[Ultrasonography diagnosis of ureteral ectopy in prostatic urethra].

A 54-year-old male who consulted for an episode of right-sided nephric colic is described. A urological ultrasound scan disclosed grade I hydronephrosis in the upper half of the right kidney and an anechoic tubular image ending in the prostate gland. A subsequent urographic evaluation confirmed the diagnosis of ectopic ureter in prostatic urethra.

Choristoma↗
PubMed1994

[Renoduodenal fistula secondary to pyonephrosis].

Presentation of one case of renoduodenal fistula due to pyonephrosis in an oligophrenic female patient. In view of the patient's characteristics, the clinical picture was highly developed at presentation which resulted in failure of the conservative treatment. We emphasize the diagnostic and therapeutical methodology followed. Also, we include a literature review on this disease.

Adult↗
PubMed1994

[An evaluation of the diagnostic efficacy of video cystourethrosonography].

Evaluation of the diagnostic capacity of lineal ultrasound examination of a male's vesical neck and urethra, known as video cysto-urethro-sonography. The tests has been shown to have high diagnostic accuracy (93.6%), with 93.4% overall sensitivity and 94.4% specificity, in a selected group of men with suspicion disease in the cervico-prostate-urethral area (prevalence, 80.9%). The technique, nevertheless, is not exempt from limitations, including anal or ureteral meatus stenosis, as well as highly obstructive prostate adenoma (where maximal vesical repletion necessary to carry out the examination may decompensate the picture, and lead to retention), or the inhibition of the voiding urge referred by certain individuals when they have to urinate in uncomfortable circumstances.

Evaluation Studies as Topic↗
PubMed1994

[The technical aspects of video cystourethrosonography].

Analysis of major methodological aspects of real time ultrasound examination of a male's vesical neck and urethra, known as video cysto-urethro-sonography (VCUS). Consideration must be given, when studying the posterior urethra, to the need of suitable vesical repletion, as well as to the existence of two likely limitations for conducting the test, such as: major anal stenosis, which would prevent introduction of the transrectal transducer; and inhibition of the voiding urge referred by some patients when they have to urinate in uncomfortable circumstances. As for the study of the anterior urethra, the most interesting technical items are: avoidance of air bubbles entering with the physiologic serum, which could artefact the examination; nonexertion of excessive compression on the urethra with the transducer, which may lead to false stenosis; and understanding that a major meatus stenosis may preclude test completion due to impossibility of introduction of Foley's catheter, necessary to obtain backward urethral distension with physiologic serum.

Humans↗
PubMed1993

[Simple calculation of prostatic weight with transrectal echography].

The appraisal of the prostate weight with transrectal ultrasound scanning is simplified with the use of a simple mathematical formula of an ovoid volume. Such a method does not prolong the examination time but provides an acceptable reliability, and therefore it can be used as a substitute to planimetry, more subject to the observer's error and more time consuming for the physician, even when part of the examination can be made by replaying the video.

Humans↗
PubMed1993

[Ureteral ectopy: report of a case of ureteral communication with vulva].

We report an uncommon case of ureteral ectopia opening to the contralateral vulva in a 20-year-old patient with a long history of night and day urinary incontinence. Since the ectopic ureter drained the superior pelvis of the right kidney, pyelo-pyelic anatomosis was performed and the defunctionalized ureter was abandoned. A completely satisfactory result was achieved. We briefly discuss this rare pathology and describe the simple, yet effective treatment.

Adult↗
PubMed1993

[Spontaneous bladder rupture: report of a case].

Contribution of one case of spontaneous vesical fracture in a patient with no urinary pathological background. Presentation of this picture is highly uncommon. In this case, a major alcoholic intake stands out as the unleashing factor which provoked vesical overdistension with an intraperitoneal posterior fracture. A review is made of the various etio-pathogenic mechanisms which can originate this pathology, as well as the diagnostic and therapeutic methodology.

Humans↗
PubMed1993

[Blue nevus of the prostate].

The presence of melanin in the prostatic gland's stroma is a histopathological finding of extreme rarity. It receives the name of blue nevus as a result of its similitude to the skin's blue nevus. The paper describes the finding of melanin stores in the fibromuscular stroma of a patient's prostate and reviews the theories on its source.

Aged↗