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Biomedical subjects

C Guérin

Publications and source records attributed to C Guérin.

At least 19 recordsLinked to original sources

[Diagnosis of caprine contagious pleuropneumonia: recent improvements].

Due to the difficulty in isolating Mycoplasma sp. type F38, two techniques for rapid detection are proposed in order to identify the presence of mycoplasmas of the mycoides group in samples of pleural fluid. A modification in the composition of isolation media promotes the growth of type F38 mycoplasmas and inhibits the growth of M. ovipneumoniae strains.

Animals

[The visco-elastic behavior of the respiratory system during mechanical ventilation. Interpretation with the aid of a model].

The purpose of this review is to present an approach to the visco-elastic properties of the respiratory system in the mechanically ventilated patient through the method of occlusion of the airways at a constant inspiratory flow rate. The ideas of airways resistance, tissue resistance, static and dynamic elastance are defined from the theoretical point of view and also from the point of view of the occlusion method. A large part is given to the bicompartmental model describing the visco-elastic properties of the lung and of the thoracic wall. Recently carried out experimental studies both in healthy man and in disease have given results which seem to confirm the predictions made by this model. According to this system the lungs may be represented as a homogenous whole surrounded by visco-elastic components.

Airway Resistance

[Evaluation of tolerance during intravenous administration of low dose of isosorbide dinitrate in the treatment of unstable angina].

The eventuality of tolerance was assessed in 19 patients with unstable angina treated by continuous intravenous infusion of 50 micrograms/min of isosorbide trinitrate (ISDN) in association with heparin and betablocker therapy. The tolerance phenomenon was evaluated by the hypotension produced by the ISDN infusion and by the amplitude of fall in blood pressure produced by an intravenous bolus of 1 mg of glyceryl trinitrate (GTN) according to the principle of crossed tolerance to the two nitrate derivatives. Under these conditions of administration, the authors observed partial attenuation of the blood pressure response to continuous ISDN infusion and absence of cross tolerance between ISDN and intravenous GTN. The co-prescription of intravenous N-acetylcysteine at a dosage of 10 g/24 hours in 10 of the 19 patients did not affect the blood pressure or the response to the GTN bolus compared with the 9 other patients who had received placebo after double-blind randomisation. The results of this study do not indicate if the maintenance of vascular sensitivity to nitrate derivatives at least for 72 hours, was related to the choice of a relatively low dose and/or the use of ISDN rather than another nitrate derivative, in particular glyceryl trinitrate. The use of intravenous ISDN at a low dose over a 3 day period in the usual conditions of prescription for unstable angina does not seem to induce a quantitatively significant phenomenon of tolerance.

Acetylcysteine

[Ureteral stenosis in kidney transplantation].

The authors report 13 cases of ureteral or periureteral sclerosis in a series of 330 cases of renal transplantation (3.9%): they occurred early, were asymptomatic (except for anuria); the renal cavities were always dilated, the renal function always deteriorated; the treatment was essentially surgical without mortality and with a low complication rate but 23% of the transplants were lost because of urological complications at 18 months. The authors compare their series with the literature.

Adult

[Transplantation and tumors of the kidney].

The authors report the case of a woman who was transplanted with a cadaveric kidney. It was a cyst on the kidney; a biopsy was performed: it was a carcinoma. The transplanted kidney was removed. The second case was a man, transplanted with a cadaveric kidney, with a tumor at the lower pole: a tumorectomy was performed: it was a angiomyolipoma.

Acute Kidney Injury

[Colonic perforation after renal transplantation].

Among surgical complications following kidney transplantation, the colonic perforation should be known. We reported a fatal case of perforation occurring on a colonic diverticulosis in the first month week post-transplantation. We emphasized on the difficulty to assess the diagnosis.

Aged

[Macroangiopathy of a kidney graft caused by cyclosporin A].

We report a case of renal macroangiopathy occurring after transplantation in a 50-year-old woman who received a cadaveric kidney and who was immunosuppressed with cyclosporin A. Accelerated hypertension at 3 months led to renal angiography which revealed diffuse narrowing of the two main renal arteries and their intrarenal branches. The patient returned to regular haemodialysis four months post-transplantation. These angiographic cyclosporin A-ascribed findings are similar to those recently reported by Sawaya.

Cyclosporins

[Arterial hypertension with renin hypersecretion secondary to pyelo-ureteral syndrome. Cure after corrective surgery].

In a 22 years old woman with recent hypertension, a timed intravenous pyelogram revealed an asymptomatic obstructive ureteropelvic junction. Preoperative renal vein catheterization demonstrated excessive renin release from the diseased kidney and low release from the other one, suggesting that corrective ureteral surgery should return blood pressure to normal levels. Moderately impaired glomerular filtration rate improved after surgery as a consequence of suppressed hydronephrosis and bilateral renal ischemia. Thus we conclude that in young people, asymptomatic unilateral hydronephrosis can lead to hypertension and renal failure like renal artery stenosis. In the other cases of urinary flow obstruction, secondary hypertension remains to be explained by both inappropriate production of renin and water chronic retention.

Adult

[Evaluation of surgical renal revascularization in renovascular arterial hypertension. Measurement by 99m Tc DTPA scintigraphy].

The effects of surgical renal revascularization on both hypertension and kidney function was assessed in 16 patients with renovascular hypertension (14 unilateral). We have taken a special interest to the split renal function studied with DTPA renogram. The function of the operated kidney was improved in 9 patients and not improved (worsened or unchanged) in 7. Hypertension was cured in 25% and improved in 56% of the patients, without correlation with split renal function outcome.

Adult

[Renal insufficiency and severe genital prolapse. 2 cases].

The authors report two patients with renal failure due to total procidentia. Surgical repair led to an improvement in renal function. Mild chronic renal failure persisted. Thus the renal status must be assessed in cases of uterine prolapse.

Acute Kidney Injury