Biomedical subjects
Publications and source records attributed to C Gros.
The patient is lying on his left side. Paravertebral muscles of the right side are separated from the spinous processes and from the right laminae. Spinous processes are then cut at their base, and hold with a strong retractor Laminectomies are then feasible, as wide as necessary. Reconstruction is particularly strong. Our 3 years experiences of 200 cases, with clinical and radiologically very good late results, is underlined.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Methionine enkephalin release was evoked by depolarization of slices from rat striatum with potassium. In the presence of 0.1 microM thiorphan [(N(R,S)-3-mercapto-2-benzylpropionyl)glycine], a potent inhibitor of enkephalin dipeptidyl carboxypeptidase (enkephalinase), the recovery of the pentapeptide in the incubation medium was increased by about 100 percent. A similar effect was observed with the dipeptide phenylalanylalanine, a selective although less potent enkephalinase inhibitor. Inhibition of other known enkephalin-hydrolyzing enzymes--aminopeptidase by 0.1 mM puromycin or angiotensin-converting enzyme by 1 microM captopril--did not significantly enhance the recovery of released methionine enkephalin. These data indicate that enkephalinase is critically involved in the inactivation of the endogenous opioid peptide released from striatal neurons.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Meralgia paresthetica although it does not produce intensive pain is a cause of chronic disability, usually barely improved by medical treatment. From the report of two cases of neurolysis the authors stress on the possibility of entrapment neuropathy of the lateral femoral cutaneous nerve in its way through the femoral canal, between the inguinal ligament and the fascia-iliaca. Anatomically, there is in this canal a normal right angle between the horizontal portion (abdominopelvic) and the vertical course in the thigh. The compression is due to a thickening of the fascia-iliaca as it forms the postero inferior wall of this canal; the nerve is squeezed between the fascia and the inguinal ligament. In 60% of cases of meralgia paresthetica where this mechanism is involved, the funicular neurolysis appears to be a radical treatment.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Using sensitive and highly specific radioimmunoassays, Met-enkephalin (Met-ENK) and Leu-enkephalin (Leu-ENK) have been shown to exist together in the retina of chicken embryo. After high performance liquid chromatography (HPLC), a fraction of the retinal extracts seems to be authentic Met-ENK. Following a G-50 filtration, the Met-ENK immunoreactivity has been found associated to three peaks, the lightest having an apparent molecular weight similar to that of the Met-ENK.
Explore the source record for details and available documents.
The particular value of clinical, radiological and electromyographical features is compared in 42 patients with motor deficit related to cervicarthrosic myelopathy or amyotrophic lateral sclerosis. The initial onset of the disease was identical (motor deficit and long tracts pathways involvement). Three different groups were identifyed according to the evolution: -- Group I: (13 cases): true lateral amyotrophic sclerosis which were not operated on. -- Group II (10 cases): myelopathy called "cervicarthrosic" because of radiological findings which were operated on but had the same steady worsened course as a lateral amyotrophic sclerosis. -- Group III (19 cases): cervical myelopathy which had surgery. The operation brought about stabilization or fairly good recovery over the 18 months following at least. From a clinical aspect, the "Lhermitte sign" or objective sensitive deficit are strongly significant for cervical myelopathy. On the contrary, diffuse fasciculations specially in the tongue seem to be mostly found in lateral amyotrophic sclerosis, whereas they are restricted into the paralysed area in cervical myelopathy. Electromyographic examination is decisive: simple activity with high frequency motor units (increased amplitude and polyphasic waves) or "preponderant potentials" into a cranial nerve territory or three segments of the lower limbs are frequently found in lateral amyotrophic sclerosis. These electromyographic features are less significant in the upper limbs. The neuroradiological findings lonely cannot assert definitely the cervicarthrosic origin of the myelopathy but visualize the conflicting situation between the spinal cord and the cervical canal and allow to choose the surgical procedure.