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Biomedical subjects

C Griffin

Publications and source records attributed to C Griffin.

84 records · Page 5Linked to original sources

Rheumatoid factor in acute bacterial endocarditis.

Sera from 55 parenteral drug abusers with endocarditis due to Staphylococcus aureus were assayed for the presence and titer of rheumatoid factor. Thirteen (24%) of the 55 patients with endocarditis had sera positive for rheumatoid factor at one point or another in their courses; only 2 (7%) of 30 noninfected drug users were found to be positive. It appeared that more severe cases, as evidenced by duration of fever after initiation of antibiotic therapy, were more likely to develop rheumatoid factor.

Acute Disease↗

Nutrition and the elderly: a case manager's guide.

This article reviews the physiological and nutritional changes associated with aging and provides the case manager with nutrition resources. General information on nutritional factors associated with aging, including common nutrient deficiences, is outlined. The dietitian's role in nutrition assessment, intervention, and outcomes is discussed. A list of resources for case managers interested in accessing a registered dietitian is also included.

Age Factors↗

MR and CT correlation of cholesterol cysts of the petrous bone.

Four patients with expansile cystic lesions of the petrous bone had correlative CT and MR scans. Characteristic findings were noted on MR scans obtained with T1- (TR = 400-800, TE = 25-32) and T2- (TR = 2000-3000, TE = 64-80) weighted images. These findings include an expansile cystic lesion centered in the petrous apex with high signal intensity on both the T1- and T2-weighted images, compatible with subacute or chronic hemorrhage. This signal pattern is distinct from the typical intradural epidermoid tumor, which has signal intensities similar to CSF with low signal on T1-weighted images and high signal on T2-weighted images. Surgical exploration yielded similar findings of a cyst containing free-flowing, brown watery fluid. Histologically, an inflammatory response was present as well as a variable number of cholesterol crystals. There was little identifiable capsular tissue but abundant evidence of subacute or chronic hematoma. The nomenclature of the etiology in these four cases is currently in some controversy, with some authors classifying these lesions as epidermoid or primary cholesteatomas while others call them cholesterol granulomas or giant cholesterol cysts. Whatever they are named, the MR image pattern is consistent and is dominated by findings indicative of hemoglobin breakdown products.

Adolescent↗

Pelvic muscles during rest: responses to pelvic muscle exercise.

The purpose of the research was to study pelvic muscle changes in the resting phase between voluntary contractions (during pelvic muscle assessment) and in response to pelvic muscle exercise (PME) through secondary analysis of data. The sample consisted of healthy women (N = 38) aged 35 to 54. Analysis of variance showed a significant difference in resting pressure within each assessment (F = 2.92, p < .04). A significant difference in resting pressures within subjects was found (F = 3.54, p < .02). Within-subject variance suggests exercises performed without a warmup may result in incomplete relaxation prior to contraction. Significant change between baseline and Level 1 of the graded PME program suggests slow relaxation of untrained muscles. Increases in resting pressure at Levels 3 and 4 may be a more accurate reflection of muscle hypertrophy. The results of this research indicate that care should be taken in establishing the point from which changes during contractions are measured. It is recommended that the resting pressure be used. Exercise continued for more than 3 or 4 weeks accounts for nearly all strength gains and explains the increases in resting pressure at PME Levels 3 and 4.

Adult↗