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Biomedical subjects

C Greenfield

Publications and source records attributed to C Greenfield.

42 records · Page 3Linked to original sources
PubMed1982

Factors affecting rehabilitation following aortocoronary bypass procedures.

Two hundred and ten men were referred consecutively to a rehabilitation program following aortocoronary bypass surgery. The program involved exercise tolerance testing 8 and 20 weeks postoperatively, with an intervening 12-week exercise program. A retrospective analysis of data showed 50% of these patients to be on no medication throughout their rehabilitation and the others on medications likely to affect cardiac performance. Factors likely to influence exercise tolerance such as age, medication and extent of revascularization were subjected to multivariate analysis in these two cohorts of patients. Age (up to 60 years) and the extent of revascularization did not appear to influence exercise tolerance. Following the 12-week exercise program, patients in both groups had improved significantly (P less than 0.01), but the initial and final performance of the cohort of patients requiring cardiac drugs was significantly poorer than those on no medication (P less than 0.01).

Adult↗
PubMed1981

Is pseudomembranous colitis infectious?

A cluster of eight patients in two adjacent hospital wards acquired acute diarrhoea within a period of 11 days. All their stool samples contained Clostridium difficile toxin and C. difficile was isolated in every case. Three patients had rectal biopsy findings compatible with pseudomembranous colitis (PMC). All the patients responded to treatment with oral vancomycin. Until the possibility of PMC being acquired by cross-infection is clarified such patients should be nursed in isolation with strict enteric precautions.

Adult↗
PubMed1980

Dimethylsulphoxide-induced toxicity.

Two elderly people were given intravenous infusion of dimethylsulphoxide (DMSO) as treatment for arthritis. One became seriously ill, the other remained well. Both had similar changes in aspartate transaminase, hydroxybutyrate dehydrogenase, and creatine kinase and evidence of haemolysis. This is the first report of serum enzyme changes and anaemia after intravenous DMSO in man.

Acute Kidney Injury↗
PubMedDate not supplied

Plasma lipid and lipoprotein response to fat feeding in alcoholic liver disease.

Serum lipids and lipoproteins were analyzed after an overnight fast, and following a fatty meal in 10 patients with cirrhosis, 5 with fatty liver, and 5 normal subjects. Cirrhotic patients were divided into two groups of five on the basis of serum lecithin-cholesterol acyltransferase activity. Fasting triglyceride levels were similar in all four groups. In all but cirrhotic patients with low lecithin-cholesterol acyltransferase activity, most fasting triglyceride was found in very low density lipoproteins; in the latter group, most of it was found in low density lipoproteins. We confirmed that patients with fatty liver have a higher serum triglyceride response to fat feeding than normal subjects, but we did not find higher levels in cirrhotic patients. Cirrhotic patients with "normal" lecithin-cholesterol acyltransferase activity had a normal triglyceride response to dietary fat. In patients with cirrhosis and low lecithin-cholesterol acyltransferase activity, the increase in triglyceride was less than in normal subjects. In this group, most of the extra triglyceride was carried in low density lipoprotein, and not in chylomicrons and very low density lipoprotein, as in the other groups.

Adult↗