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Biomedical subjects

C Graham

Publications and source records attributed to C Graham.

144 records · Page 8Linked to original sources

Genital herpesvirus hominis type 2 infection: an experimental model in cebus monkeys.

Genital infection with herpesvirus hominis type 2 was established in ten female cebus monkeys. Clinical and laboratory findings in the cebus mimic closely those observed in humans, thus providing an experimental model which may be used in the study of the possible role of genital herpetic infection in cervical cancer and in perinatal and chronic neurological diseases.

Animals↗

Diazepam and lorazepam for intravenous surgical premedication.

Diazepam, 10 and 20 mg, and 2 and 4 mg lorazepam were studied as intravenous surgical premedicants in 120 patients. Relief of anxiety, sedation, patient acceptance, lack of recall, and side effects were the variables evaluated. Both diazepam and lorazepam proved to be excellent surgical premedicants. The basic difference between the two drugs is temporal. Both medications produce similar relief of anxiety, sedation, patient acceptance, and lack of recall. The clinical effects of intravenous diazepam peaks in 2 to 3 minutes and diminishes thereafter. Intravenous lorazepam has a latent period of 8 to 15 minutes, with increasing effects at 15 to 30 minutes.

Adolescent↗

Rehabilitation of a paraplegic prisoner: conflicts for patient and nurses.

The most frequent outcome of a physical rehabilitation program is discharge to an independent or assisted-living environment in the community. When a patient remains incarcerated throughout a rehabilitation stay and is returned to a prison at discharge, both patient and nurse can experience conflicts caused by differences in the two settings. This article presents a case study in which conflicts that occurred and strategies for their resolution are discussed.

Adult↗

Do rehabilitation patients continue prescribed bowel medications after discharge?

An exploratory descriptive study was conducted to address the use of bowel medications 1 month after discharge from an inpatient rehabilitation center and the rationale for making changes from bowel medications prescribed at discharge. At discharge, 66% of the 114 participants took bowel medications, but 1 month later, 42% did. Stimulant laxatives accounted for nearly half the medications taken at each point. Most of the patients who made medication changes reduced the prescribed dose or altogether discontinued taking the prescribed medication. In response to open-ended questions about changes, participants gave reasons related to physiology and personal preference. Anticipating that many patients will change their bowel medications after discharge, practitioners need to consider patients' preferences and teach patients how to adjust their medications correctly.

Adult↗

Pulmonary artery dissection: MR findings.

We report a case of pulmonary artery dissection imaged by MR. Dissection of a markedly dilated pulmonary artery is a rare and usually fatal complication of chronic pulmonary arterial hypertension. The diagnosis is made at autopsy, with only two cases having previously been documented (by Doppler echocardiography) during life. The hallmark of an arterial dissection is the finding of an intimal flap and a false lumen. In our case, spin echo MR imaging failed to show either the intimal flap or any intraluminal signal defects. The dissection was presumably obscured by nonhomogeneous intraluminal signal caused by the slow blood flow associated with severe pulmonary arterial hypertension. Cine MR imaging, however, demonstrated different signal intensity within the true and false lumens of the dissection, thereby outlining the intimal flap between the two channels.

Adult↗

Exercise options for persons with diabetic complications.

Exercise is a cornerstone in the management of diabetes, yet many persons with diabetes fail to participate in basic physical activity due to secondary diabetic complications. This inactivity can lead to disuse syndrome--a deterioration of functional capacity. Disuse syndrome, coupled with diabetes, can produce significant physiological problems and further disability. This review provides the health educator with information about the pathology and role of exercise for persons with diabetic complications. Examples of exercise to minimize disuse syndrome are given for individuals with peripheral vascular disease, retinopathy, neuropathies, and nephropathy.

Diabetes Complications↗

Exercise and aging: implications for persons with diabetes.

Physiological systems decline with age. Such declines may be the result of aging itself or physical deconditioning. Evidence suggests that the degree to which decrements occur with aging may be modifiable with physical activity. The elderly adapt to exercise programs at a generally reduced rate. Thus reduced activity, coupled with diabetes, may present unique clinical needs. In the design of exercise programs for the elderly person with diabetes, special attention needs to be given to medical screenings, potential risks, exercise goals, and implementation.

Aged↗

Needs assessment of non-traditional students in physical and occupational therapy programs.

A 104-item questionnaire was utilized to assess the financial, family, educational, and psychosocial needs of 196 non-traditional students enrolled in physical or occupational therapy programs. Quantitative data were analyzed using descriptive statistics and analysis-of-variance procedures. Open-ended questions were analyzed using qualitative data analysis. Results indicated that 65% of the subjects agreed or strongly agreed that their overall educational, family, financial, and psychosocial needs were being met while in the program. Teaching-learning preferences included clinical experience, laboratory practice, and studying alone rather than in groups. Local clinical placements and stipends were seen as more beneficial in assisting with financial burdens than part-time or night/weekend class scheduling. Qualitative themes included family and financial stress, difficulty adjusting to the student role, value of maturity and life experience, value of peer teaching, and development of coping strategies. The authors recommend provision of a comprehensive orientation for non-traditional students, mechanisms to facilitate networking, resources for readjusting to the student role, and enhanced financial aid opportunities.

Adaptation, Psychological↗