Biomedical subjects
C Gospos
Publications and source records attributed to C Gospos.
[Proceedings: 1. Gout. Acute bullous dermatosis. 2. Latent diabetes mellitus and hyperlipoproteinemia type IV Fredrickson].
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[Acute fulminating ulcerative colitis with toxic megacolon].
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[Necrosis of the prostate and the urinary bladder during kumarin therapy (author's transl)].
The very first case of part necrosis of the ruinary bladder and prostate during therapy with kumarin is presented. The pathogenesis of kumarin induced necrosis is discussed. Apart from other findings there was histologically proved thrombosis of arteries and veins.
[Cystinosis (author's transl)].
Cystinosis (syn. crystine storage disease) is inherited as an autosomal recessive trait. The severety of clinical symptoms may vary considerably. The most severe form of nephropathic cystinosis causes death of the affected patients at the age of 2 to 4 years (subacute course) or before puberty (primary chronical course). Three autopsy cases are demonstrated. Each of these children died from complications of chronic renal failure, caused by kidney contraction as a sequela of chronic interstitial nephritis. Cristalline cystine deposits were found in the renal interstium as well as in the RES cells of spleen and liver. Because of water solubility of L-cystine aqueous fixation and staining solutions must be avoided. Diagnostic doubly refractive brick- or needle-shaped cystine cristals can be demonstrated in frozen sections or tissue smears from spleen, liver, lymphnode and bone marrow.
Scanning electron microscopic (SEM) studies on the effect of x-ray contrast media on aortic endothelium in the rat.
A study comparing the effects of diatrizoate, ioxitalamate, metrizamide, ioxaglate, and a 22% sorbitol on aortic endothelia of the rat was performed. In each case 1 ml of the respective solution was injected in a single dose into the aorta. Endothelial damage was seen after injection of metrizamide, diatrizoate, and ioxitalamate. After injection of ioxaglate or sorbitol, only minor endothelial changes were observed.
Percutaneous transluminal treatment of supraaortic artery obstruction.
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