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Biomedical subjects

C Gonzales

Publications and source records attributed to C Gonzales.

63 records · Page 4Linked to original sources

Effects of dobutamine on atrioventricular conduction.

Dobutamine, a new beta-stimulating catecholamine, has been investigated in terms of its effect upon atrioventricular conduction. Bundle of His recordings were obtained on six patients in basal conditions and with right atrial pacing at rates of 100, 120, and 140 per minute. Recordings were repeated following intravenous administration of Dobutamine in doses of 5, 10, and 15 mug per kilogram per minute. Dose-response curves were thus obtained for A-H and H-V intervals. Heart rate increased only moderately with progressive concentrations of the drug. Very significant facilitation of A-H conduction was demonstrated with doses of 10 and 15 mug per kilogram per minute, with no effect upon H-V times. Dobutamine may be a clinically useful inotropic agent in conditions associated with A-V conduction disturbances.

Adult↗

Mammography and Pap smear screening of Yaqui Indian women.

The Pascua-Yaqui Tribe of Arizona receives its health care services at a local neighborhood health center in Tucson and a satellite clinic located on the reservation. Using a computerized data base from the health center, the authors determined the use rates by Pascua-Yaqui women ages 35-65 of the Papanicolaou smear and mammography screening. Among active users of the health center, 31-36 percent had received a Papanicolaou smear, according to the yearly data bases examined from 1986 to 1990, while 65 percent of the women had received at least one smear test over the entire 5-year period. Regarding mammography screening, 41-43 percent of the women ages 50-65 had received a mammogram in the years studied, and 51-58 percent of the women ages 40-49 had been screened. In all, 67 percent had received at least one mammogram during the 1988-90 period when the center offered mammography. This population of 35-65-year-old American Indian women, for whom financial access is not a barrier, were receiving Papanicolaou smears and mammograms at rates comparable with other segments of the U.S. population but at lower rates than those recommended by the American Cancer Society and National Cancer Institute. The challenge for the health center is to reach those women who are eligible for services but do not use them and to address the nonfinancial barriers to care such as language, transportation, and gender-specific issues.

Adult↗