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Biomedical subjects

C Goldberg

Publications and source records attributed to C Goldberg.

At least 55 records · Page 3Linked to original sources

Primary orbital schwannomas.

Seven histologically proved cases of primary orbital schwannoma have been seen at the University of British Columbia Orbital Clinic between September 1976 and December 1980. We describe here their varied clinical presentations, preoperative investigations, operative findings, and appearances on light and electron microscopy. Although no single feature is pathognomonic, a multiplicity of clinical, radiographic, and surgical features point to this lesion. Of preoperative investigations the computed tomography scan was the most helpful, especially in localising the lesion. Of the 7, 4 were intraconal and 3 were extraconal. The surgical approach was dictated by tumour site and included anterior, lateral, and panoramic orbitotomies. At surgery the nerve of origin of 4 of the tumours was identified. All tumours were excised totally or subtotally. There has been no recurrence to date.

Adult↗

Assessment of gestation by ultrasound in various stages of pregnancy in infants differing in size and ethnic origin.

A clinical assessment of gestational age after birth has been compared with the ultrasound measurement in utero at various stages of pregnancy in a population of mixed socio-economic status and racial origin. In infants who were small-for-dates or large-for-dates at birth, accurate prediction from ultrasound measurement could only be achieved if the crown rump length or the biparietal diameter was measured before 20 weeks gestation. At this time, the infants destined to be small-for-dates or large-for-dates at birth show no growth retardation or acceleration. There is also no influence of racial origin on the measurements.

Birth Weight↗

Causal attribution of success and failure as a function or authoritarianism and sex.

We predicted that authoritarian actors would engage in defensive attribution, and authoritarian observers would derogate the other, to a greater extent than egalitarian perceivers. 48 male and 48 female college students were run in pairs of same sex and authoritarianism. A set of easy anagrams was given to subjects in success conditions and difficult anagrams to those in failure conditions. Each subject rated own outcome and other outcome in terms of internal factors of ability and effort, and external factors of task and luck. We found that authoritarian actors were more internal than egalitarian actors only in the condition own success-other's failure. Authoritarian observers, as compared to egalitarians, were more external for other's success and more internal for other's failure only when own outcome was successful. It seems that authoritarian perceivers exaggerate their abilities and derogate the other only when they are clearly in a superior position vis-a-vis the other. There were no sex differences as a function of outcome and authoritarianism.

Achievement↗

Interferences in the delta-aminolevulinic acid dehydratase (ALA-D) assay.

A systematic study of the effect of procedural variables on the ALA-D assay has been carried out. Because of metal content in vacutainers, artifactual results are obtained on blood samples drawn by this method and the method of choice is the use of plastic syringes and tubes. The use of isopropyl alcohol as a skin sterilizing agent, although it gives measurable blood alcohol readings, does not affect the ALA-D assay. The handling of the whole blood has been investigated and the two methods of hemolysis compared. Trichloroacetic acid, a reagent used in the final assay of porphobilinogen, has been found to be a serious interference in the method, making it essential for this reagent to be kept in a securely sealed container. The deterioration of the trichloroacetic acid--mercuric chloride reagent is also a potential procedural problem that must be considered.

1-Propanol↗

Kyphectomy in children with myelomeningocele: a long-term outcome study.

Twenty-four children with myelomeningocele and a kyphotic deformity treated by surgical correction between 1980 and 1994 were reviewed. Different techniques of instrumentation and spinal fusion were used. The mean age at surgery was 9.5 years. The mean kyphotic angle was 121 degrees preoperatively, 50 degrees postoperatively, and 57 degrees at final follow-up. The postoperative complication rate was high. Delayed wound healing and late skin breakdown with exposure of instrumentation were common problems. Further surgery to remove protruding hardware was necessary in 18 patients. Long posterior instrumentation with fixation to the pelvis had significantly better stability on follow-up than other methods. Despite the prolonged postoperative morbidity in the majority of the study group, the long-term clinical and radiologic outcome at a mean follow-up of 10 years was excellent.

Adolescent↗