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Biomedical subjects

C Gillot

Publications and source records attributed to C Gillot.

At least 91 records · Page 5Linked to original sources

[Nocardia otitidiscaviarum, cutaneous infection in a patient receiving long-term corticosteroid treatment].

A 62-year-old man, under long-term corticosteroid therapy for pigeon breeder's disease, was admitted to endocrinology disease department for cutaneous abscess on back, limbs and scalp. Culture of various bacteriological samples (cutaneous abscess, blood culture) isolated Nocardia otitidiscaviarum. The patient was treated by trimethoprime-sulfametoxazole during several weeks with abscess disappearance. Our laboratory quickly identificatied a bacteria belonging to the Nocardia genus, with simple technique, later confirmed by a specialized laboratory (Pr. Boiron Claude Bernard University Lyon I) with identification of Nocardia otitidiscaviarum. The proof of pulmonary nocardiosis could not be established despite the existente of several risk factors. Prognosis is poor for immunocompromised patients, but the secondary cutaneous dissemination phase presented a favourable evolution under antibiotic therapy.

Adrenal Cortex Hormones↗

[Postural obstruction of the popliteal vein. Its role in deep venous insufficiency of the legs].

Postural or, more generally, positional obstruction of the popliteal vein occurs either in complete extension of the leg, or in powerful flexion of the order of 90 degrees. It is sometimes constitutional and sometimes acquired, as a result of dystrophy of the venous wall. Abnormal phlebographic appearances vary according to the position of the leg and the level of the obstruction: signs of narrowing or axis displacement with the knee in extension; plications, sinuousities, stenosis, curved imprints with the knee in flexion. The actual existence of circulatory slowing has been confirmed by Doppler. Hemodynamic consequences appear to be all the more severe when the obstruction is tighter, situated higher and when the great saphenous itself is narrowed at the level of the popliteal crease. Despite its intermittent nature, positional obstruction must be kept under consideration: in hospital medicine, because of the potential danger of venous stasis which it causes, with the risk of underlying thrombosis; in everyday phlebology, since it explains, to a certain extent, the mechanisms of chronic venous insufficiency occurring after standing upright or sitting for prolonged periods. Awareness of this possibility forms the basis of a number of general rules concerning good venous health, certainly by no means original but rarely observed.

Constriction, Pathologic↗

[Variations and valve structure of the truncal femoro-popliteal system].

Study of valves is inseparable from that of the main veins in which they are located. While a modal femoro-popliteal system, satellite to the arterial system, is by far the commonest, major variations are seen in approximately 10% of cases. Each main collecting vein has its specificity, according to its width, the course which it follows and whether or not there is a satellite wide calibre artery. Additional features include the chief affluents which its receives, wavering of its course, the supple or rigid perivascular environment and the proximity of large muscle masses. All these features play a role in the quality of drainage, in particular during exercise, and in anti-reflux function. In practice, variations come down to two broad possibilities: the single collector, sometimes made up of several different embryological segments, resulting in a hybrid vessel and an aberrant course, either axial, satellite to the sciatic nerve, or profunda femoris, satellite to the shaft of the femur. Doubling (bifid or by bifurcation) opens up an additional channel, either parallel or divergent, which considerably modifies the conditions of venous return. A lesion affecting one branch only, e.g. a solitary thrombus, may have no clinical manifestations and marking if collectors during imaging. The topography of the valves of the main veins tends to be fairly fixed. They are preferentially located proximal to the main confluents, to winding parts of the course of the vessel, or at certain hemodynamic levels which vary little from one individual to another. An attempt is made at nomenclature, classification and topography. The chief feature, the terminal valve of the lower limb, is located most often at the femoral ring. It alone is capable of opposing the long cavo-iliac reflux caused by effort. Analysis of retrograde phlebography films with caval occlusion shows that reflux is not directly exerted on the valve. The point of interruption is high, in the terminal portion of the external iliac vein. This hemodynamic barrage is purely functional. When there is incontinence of the terminal valve varying degrees of reflux diffusely affect the femoral axis. At the same time, there is regurgitation of contrast medium into the visceral areas of the true pelvis, normally sealed off. This coupling between anti-reflux function of the lim and that of the pelvis is one of the unexpected aspects of valve activity.

Blood Circulation↗

[Saphenectomy in patients over 65. Indications and results].

For 779 patients who underwent varicose vein surgery at Bicêtre, between 1981 and 1984, there were 61 elderly patients between 65 and 74 years and 15 "old age" patients over 75 years. Only one severe complication occurred. Almost all patients who were operated upon were satisfied or very satisfied to see that the functional discomfort had disappeared, the trophic disorders had regressed, the superficial phlebitis or hemorrhages had not recurred and the ulcer were healed. Statistics are in favor of a surgical treatment of varicose veins or phlebitis sequellae with severe degeneration of the superficial venous network, as soon as they become uncomfortable, because of the increased life expectancy, in Europe at this time. But, because of the tremendous progress of anesthesia techniques, it seems permissible to offer this surgical procedure to those who have passed the age previously considered as reasonable and are quite disabled.

Aged↗

[Biradicular origin of the popliteal vein].

The biradicular origin of the popliteal vein was affirmed 84 times out of 100 dissections, and confirmed by phlebography. But the anatomical bifurcation fades into insignificance beside the important notion of functional bifurcation, with strong roots, equal to or above 5 mm. It exists in this form in 56% of all cases. The most interesting arrangement in practice is the popliteal fork with equilibrated medial and lateral roots, absolutely equal, or only very slightly asymmetric. This variety, observed 21 times, uni- or bilateral, leads us to reconsider the investigative methods in the diagnosis of popliteal thrombosis. In reparatory arterial surgery, if offers a radicular graft of excellent calibre, with a well built wall, but which is perhaps limited for such a purpose.

Humans↗

[The saphenous system. Medial approach to the arterial axis of the lower limb].

It is possible, by means of a continuous succession of incisions, transferred onto the course of the long saphenous vein, to approach all the vascular trunks in the lower limb, from the area of the femoral triangle, to the lower third of the leg. Two original approaches are described: by way of the deep distal femoral artery, or perforator trunk, which has the chief advantage of enabling the practitioner to operate away from the inguinal ganglions; and the transmembranous approach via the anterior tibial artery in the middle third of the leg, with the object of implanting the long saphenous vein without diverting its course.

Femoral Artery↗

[Surgical anatomy of perforating veins of the leg].

The saphenous trunks of the leg and their main perforators extend from the tibia to the axis of the calf. The external saphenous vein (little saphenous vein) is often isolated; on the contrary, there is an internal saphenous system including, in addition to the main trunk which is often divided, anterior and posterior saphenous veins, as a possible support for the perforators. The calf's reticulum, network of veinlets reinforced with arches, is a group of intersaphenous anastomosis. The retro-tibial perforators (Cockett's or Boyd's) reach the posterior tibial veins through a direct route. The muscle perforators are connected with the soleus and medial gastrocnemius veins; ventrally, elements from the internal saphenous system are present, as well as axial branches on the external saphenous vein and interperforating longitudinal anastomoses. The ventro-lateral perforators, tributary of the anterior tibial and peroneal veins, are accessory.

Humans↗