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Biomedical subjects

C G Semple

Publications and source records attributed to C G Semple.

41 records · Page 3Linked to original sources
PubMed1982

The pituitary-testicular axis of uraemic subjects on haemodialysis and continuous ambulatory peritoneal dialysis.

Pituitary-testicular function was evaluated in 18 patients with chronic renal failure, 9 treated by maintenance haemodialysis (HD) and 9 by continuous ambulatory peritoneal dialysis (CAPD), and compared with a non-uraemic control group. Serum total testosterone and the free testosterone index were significantly low in both dialysis groups. Basal FSH and LH levels were elevated but this reached significance only with regard to LH. The responses of both FSH and LH to the iv administration of LRH were normal. There was no significant difference between the CAPD and HD groups in any of the hormonal parameters estimated. While CAPD may improve control of some metabolic parameters when compared with HD, it does not improve the function of the pituitary-testicular axis.

Adult↗
PubMed1981

Tampon-associated toxic shock syndrome--a case report.

We report a case of tampon-associated toxic shock syndrome occurring in a 16-year-old girl. While this condition has been reported almost exclusively from the USA it is likely that TSS will be recognised elsewhere with increasing frequency as physicians become more aware of its existence. We consider that TSS must be considered in any hypotensive female in the reproductive age group with diarrhoeal illness.

Adolescent↗
PubMedDate not supplied

Do different frequencies of self-monitoring of blood glucose influence control in type 1 diabetic patients?

The effect of altering the frequency of self-monitoring of blood glucose upon blood glucose control was assessed in 25 Type 1 diabetic patients. Patients entered a balanced, crossover study in which they were randomly allocated to three 12-week periods. During each period the frequency at which patients self-monitored their blood glucose was: (1) four-point profiles on 2 days per week; (2) four-point profiles on 1 day per week; (3) two-point profiles on every day of the week. There were no significant differences in mean blood glucose concentration, fructosamine or glycosylated haemoglobin concentrations during the three periods. There was no correlation between the frequency at which patients altered insulin doses and measures of metabolic control. Altering the frequency of blood glucose self-monitoring had a variable and uncertain influence upon the frequency at which patients altered insulin doses. Some patients felt unsafe monitoring blood glucose only four times per week. There was however no patient consensus on the best-liked regimen.

Adult↗