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Biomedical subjects

C G Nilsson

Publications and source records attributed to C G Nilsson.

84 records · Page 5Linked to original sources

Endometrial morphology of women using a d-norgestrel-releasing intrauterine device.

Endometrial biopsies were obtained from 12 volunteers treated with d-norgestrel-releasing intrauterine devices (IUDs) with two different release rate. Four subjects scheduled for hysterectomy had d-norgestrel-releasing IUDs inserted approximately 1 month prior to surgery. The effect of d-norgestrel on the endometrium and fallopian tubes of the removed uteri was examined. A uniform suppression of the endometrium with glandular atrophy and decidualization of the stroma was found in all of the endometrial specimens. Moreover, changes similar to those observed during the luteal phase and early pregnancy could be seen in the tubal epithelium.

Adult↗

Plasma prolactin concentrations in women treated with low dose combination type oral contraceptives and in women using a d-norgestrel-releasing intrauterine device.

Plasma prolactin was measured in fourteen fertile women during a control cycle and during treatment with two different types of contraception. Ten of the women received a low dose combination type oral contraceptive, while the other four had a d-norgestrel-releasing intrauterine device (d-Ng-IUD) insereted. Plasma samples were corrected in the follicular and luteal phases during the control cycle and the treatment cycles in the d-Ng-IUD-group. In the oral contraceptive group, the samples were collected before treatment, three weeks, and again three months after the beginning of treatment. The results in the different grolups and the different phases of the cycles were compared, but no significant differences were found.

Adult↗

Biodegradable polylactate as a steroid-releasing polymer: intrauterine administration of d-norgestrel.

Polylactate film containing 30 per cent or 4.5 mg. of d-norgestrel was fixed around a plain T-IUD and the device was inserted into the uterine cavity. Norgestrel was gradually released into the systemic circulation, blood levels being highest during menstruation. Plasma estradiol and progesterone determinations revealed that cyclic ovarian function was maintained during the intrauterine administration of norgestrel; however, marked local effects on the endometrium resulted. The amount of menstrual bleeding was reduced.

Adult↗

The environmental somatization syndrome.

Patients with environmental somatization syndrome (ESS) believe that their symptoms are caused by exposure to tangible components of the external environment or by ergonomic stress at work. ESS is distinguishable by mental contagiousness and by the patients' focus on the external environment as cause of the illness. The presentation is often polysymptomatic, and epidemic outbreaks may appear. The patients usually refuse alternative explanations of their symptoms and discredit and reject any suggestion of a psychogenic etiology. It is important to distinguish between hygienic problems and ESS problems, particularly when poor and inadequate hygienic factors are present simultaneously with an ESS epidemic.

Diagnosis, Differential↗