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Biomedical subjects

C G Johnson

Publications and source records attributed to C G Johnson.

41 records · Page 3Linked to original sources

Does physician uncertainty affect patient satisfaction?

Physicians may choose one of several strategies when initially uncertain about making a specific therapeutic recommendation. The authors investigated how patients' satisfaction is affected by disclosure of uncertainty and its attempted resolution during a clinical encounter. Three hundred and four patients awaiting appointments at a university hospital's ambulatory medical clinic were randomized to view one of five videotapes (VTs) of a patient seeking advice about antimicrobial prophylaxis for a heart murmur. In VT-1 and VT-2, the physician disclosed no uncertainty and prescribed therapy. In VT-3, VT-4, and VT-5, the physician openly conveyed uncertainty but then: (VT-3) prescribed antibiotics without resolving his uncertainty; (VT-4) consulted a reference book with the patient present, then prescribed; or (VT-5) checked a computer with the patient present, then prescribed. Patients rated their satisfaction with the physician on a standardized questionnaire. Differences in satisfaction between the five VTs were significant (p = 0.001), with the highest ratings found for VT-1 and VT-2, where no uncertainty was disclosed. The lowest ratings in satisfaction were found when the physician expressed but then ignored uncertainty (VT-3) or examined a textbook (VT-4). Global satisfaction was inversely and significantly correlated (r = -0.47) with the patients' perception of uncertainty in the physician. The manner in which clinical uncertainty is disclosed to patients and then resolved by the physician appears to affect patients' satisfaction.

Ambulatory Care↗

The effect of TNFa on bradykinin receptor binding, phosphatidylinositol turnover and cell growth in human A431 epidermoid carcinoma cells.

In this study, we examined the effect of TNFa on bradykinin (BK) B2 receptor binding and function in human A431 epidermoid carcinoma cells. [3H]BK binds to a single class of receptors on A431 cells in a saturable and reversible manner. A binding affinity (KD) of 3.0 +/- 0.3 nM (n = 4) and a Bmax of 151 +/- 14 fmols/10(6) cells, representing approximately 90,000 BK receptors per cell, was observed. The rank order of potency for BK agonist peptides indicates that the A431 BK receptor appears to be of the B2 subtype. When A431 cells were incubated with TNFa (10 ng/ml) for 48 h prior to BK binding, a significant decrease in the number of BK receptors compared to control was observed. TNFa did not influence the affinity of BK binding to A431 cells and direct addition of TNFa to the binding assay did not effect BK binding. BK-stimulated IP1 formation appeared to be increased in TNFa treated cells compared to control whereas histamine-stimulated IP1 formation was not influenced. Both control and TNFa treated cells were greater than 95% viable. However, TNFa treated cells were blocked in the G1 phase of the cell cycle resulting in a decrease in DNA synthesis. This may be one mechanism for the TNFa-induced decrease in BK receptors in A431 cells.

Bradykinin↗

Evaluating preceptorship experiences in a distance nursing program.

Clinically based education for registered nursing students is a major component of a nursing curriculum. Nursing educational programs are becoming increasingly reliant on clinicians in hospitals and health care agencies to be preceptors for their students. The concept of preceptorship in baccalaureate nursing education continues to be endorsed as a viable alternative clinical teaching strategy (Myrick & Barrett, 1994). Preceptorship programs are necessary interventions to facilitate integrating and enacting the professional nurse role (Allanach & Jennings, 1990). The educational clinical preceptorship provides the opportunity for collaboration and the development of collegial relationships between members of academia and nursing service (Patton & Dowd, 1994). The highly competitive nature of today's health care institutions and the rapid changes in health and nursing care increase the need for nurse leaders. Students must acquire leadership and management skills and be competent as the role of the nurse changes to a participant in the organizational leadership and management process. The purpose of this study was to evaluate students' experiences regarding preceptor effectiveness in upper division leadership and management courses in a Bachelor of Science in Nursing (BSN) distance nursing program. Specifically, this article describes experiences from participating students enrolled in a performance/clinical rotation in the Spring 1996 semester throughout the state of California. For a successful clinical experience, it is important to evaluate the major components of the preceptorship experience.

Adult↗