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Biomedical subjects

C Fricker

Publications and source records attributed to C Fricker.

17 recordsLinked to original sources
PubMed2004

Heterotrophic plate count measurement in drinking water safety management: report of an Expert Meeting Geneva, 24-25 April 2002.

A group of microbiology and public health experts including regulatory and medical expertise was convened in Geneva, Switzerland, 25-26 April 2002 to consider the utility of heterotrophic plate count (HPC) measurements in addressing drinking water quality and safety. The group was convened following the NSF International/World Health Organization Symposium on HPC Bacteria in Drinking Water--Public Health Implications? The Expert Meeting was attended by 31 participants from Australia, Canada, France, Germany, Italy, Japan, the Netherlands, South Africa, Switzerland, UK and USA.

Bacteria↗
PubMed1998

Effects of starvation on physiological activity and chlorine disinfection resistance in Escherichia coli O157:H7.

Escherichia coli O157:H7 can persist for days to weeks in microcosms simulating natural conditions. In this study, we used a suite of fluorescent, in situ stains and probes to assess the influence of starvation on physiological activity based on membrane potential (rhodamine 123 assay), membrane integrity (LIVE/DEAD BacLight kit), respiratory activity (5-cyano-2,3-di-4-tolyl-tetrazolium chloride assay), intracellular esterase activity (ScanRDI assay), and 16S rRNA content. Growth-dependent assays were also used to assess substrate responsiveness (direct viable count [DVC] assay), ATP activity (MicroStar assay), and culturability (R2A agar assay). In addition, resistance to chlorine disinfection was assessed. After 14 days of starvation, the DVC values decreased, while the values in all other assays remained relatively constant and equivalent to each other. Chlorine resistance progressively increased through the starvation period. After 29 days of starvation, there was no significant difference in chlorine resistance between control cultures that had not been exposed to the disinfectant and cultures that had been exposed. This study demonstrates that E. coli O157:H7 adapts to starvation conditions by developing a chlorine resistance phenotype.

Bacteriological Techniques↗
PubMed1995

[Are degenerative joint diseases chronic compartment syndromes?].

An increase of the intraosseous pressure is observed in the epiphyses of bones involved in degenerative joint disease. The increase of pressure may be caused by an accumulation of osmotically active substances in the interstitium as it has been described in case of the Compartment Syndrome. Based on the postulated pathophysiological mechanism a causative therapy of the degenerative joint disease is proposed.

Animals↗
PubMed1994

[Are degenerative joint diseases chronic compartment syndromes?].

An increase of the intraosseous pressure is observed in the epiphyses of bones involved in degenerative joint disease. The increase of pressure may be caused by an accumulation of osmotically active substances in the interstitium, as it has been described in case of the compartment syndrome. Based on the postulated pathophysiological mechanism, a causative therapy of degenerative joint disease is proposed.

Algorithms↗
PubMed1994

The effect of an alternate environment as a collection medium on the permeation characteristics of solid organics through protective glove materials.

With a method developed for the determination of permeation characteristics of glove materials by organic solids, a study of the effect of a saline environment on permeation characteristics such as breakthrough and steady state permeation was performed at ambient temperature. The study uses saline as a collection medium and a stainless steel permeation cell designed exclusively for solids. The system allows for materials of five commercially available gloves to be exposed to nine organic solids. Natural rubber latex yielded the shortest and nitrile the longest breakthrough times. Overall, breakthrough times were comparable to a method using a helium collection medium, but in many exposures the saline-based collection medium yielded longer breakthrough times, 2% to 894%. In the testing involving the saline collection medium, results showed that the polarity of the glove material may be a factor that reduces measured permeation rate.

Gloves, Protective↗
PubMed1992

Protective glove material permeation by organic solids.

A method has been developed for the determination of permeation characteristics of glove materials by organic solids. The system employs a stainless steel exposure cell and allows rapid and uniform contact of either solid disks or powders with minimal membrane bowing. A gas chromatograph equipped with a flame ionization detector was used for monitoring the permeation process, which provided detection limits of 0.9-1.2 ng for the organic solids evaluated. By using an automated system for instrument control and data collection, breakthrough times, steady-state times, and steady-state permeation rates have been determined for five common glove materials when exposed to nine organic solids.

Benzoquinones↗
PubMed1982

Occlusion of the digital arteries -- A model for pathogenesis of navicular disease.

The digital arteries of 10 horses suffering from navicular disease, and 7 horses from a control group, were examined angiographically. The horses from the disease group showed complete or partial occlusion of the digital arteries in all cases. In the control group of 7 healthy horses, isolated vessel obstructions were also found but these were limited to narrowing of part of an artery only. Histological investigations showed that total occlusion of a vessel involved an organised thrombus but that partial occlusion generally involved changes to the vascular wall, similar to those caused by endarteritis obliterans. The vessel changes are discussed, with particular reference to their possible significance as a cause of navicular disease.

Animals↗