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Biomedical subjects

C Frey

Publications and source records attributed to C Frey.

6 recordsLinked to original sources

[Intellectual and neurological development of 9-15-year-olds who were born as at-risk neonates].

This retrospective study deals with 296 children born between 1, Jan. 1974 and 31, Dec. 1980, who had been hospitalized as newborns at the Department of Pediatrics of the University of Berne and who had been considered at risk for abnormal psychomotor development because of well defined perinatal risk factors. Their psychomotor development had first been evaluated in the first months and years of life at the Cerebral Palsy Centre at Berne. In 1989, when the children were 9-15 years old, their neuro-intellectual development was investigated through a questionnaire sent to the families dealing with the subsequent psychosocial and scholastic course. In the CP-Centre, at a median age of 10 and mean age of 26.4 months, 247 (83.5%) of the children had been discharged with the finding of normal psychomotor development, 25 (8.4%) had been considered to show questionable findings and 24 (8.1%) to show obvious abnormal psychomotor development. On the basis of the answers to the questionnaire (median age 11 8/12, mean age 11 10/12 years; 62% return rate), 39.3% of the children had had no further problem, and 57.4% had used special support such as speech therapy or educational consulting and/or had had school problems. 3.3% showed distinct learning disabilities. More than 90% were attending a normal public school. This corresponds to the attendance in the general population. However, fewer children were in higher schools. To investigate whether the judgement in the first months and years (CP-Centre) of life corresponded to the further development (questionnaire), a subpopulation was specially evaluated in addition.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent

[Prevention of thromboembolic complications in transurethral resection of the prostate (author's transl)].

1. The effect of 2 X 500 ml Dextran 70 i.v. for prevention of postoperative deep vein thrombosis in patients with transurethral resection of the prostate was investigated in a controlled, prospective and randomized study. The diagnosis of deep vein thrombosis was made by means of the 125I-fibrinogen test. 2. A total of 86 patients were studied. Two out of 47 in the control group developed deep vein thrombosis and 3 out of 39 in the dextran group. The total number of all thromboembolic complications in the control group is 19.2% as compared to 7.7% in the dextran group. This difference is statistically seen not significant. 3. Dextran prophylaxis showed no side effects. 4. A search of the literature on thromboembolic complications in urology shows the following. The incidence of deep vein thrombosis is general urology is about the same as in general surgery, i.e. every third patient develops deep vein thrombosis. There are no studies which would show that the number of fatal pulmonary emboli can be significantly reduced by any sort of preventive method in urologic patients. 5. The incidence of deep vein thrombosis in open prostatectomies is around 50%. In transurethral resection, however, this figure is between 5 and 10%. But nevertheless there are fatal pulmonary emboli. There exist no studies showing a significant reduction in the incidence of deep vein thrombosis after prostatectomy by any form of prevention. In order to avoid the postthrombotic syndrom and fatal complications, a prevention of thromboembolism seems reasonable, if this form of prevention has minimal side effects.

Adult

A new technique for hemipelvectomy.

A new technique for hemipelvectomy has been developed in which a large anterior well vascularized flap is used. The preservation of an anterior flap is essential if the posterior flap cannot be preserved because of tumor involvement. The vascularized anterior flap may be superior to the posterior flap because of less dermal necrosis. Use of the anterior flap may increase the ease of hemipelvectomy and reduce blood loss at operation.

Adult

[Modification of smoking behavior using long-distance methods].

906 persons willing to quit smoking were allocated at random to several groups. The results show that (1) an extract of avena sativa has no effect on quantity smoked; (2) distribution of the various parts of a smoking cessation program over several days was no more effective than distribution at once; (3) stopping at once was more effective than progressive reduction of cigarettes smoked.

Edible Grain