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Biomedical subjects

C Fontaine

Publications and source records attributed to C Fontaine.

At least 37 records · Page 2Linked to original sources

[Extensor tendon rupture after dorsal surgery of the rheumatoid wrist: analysis of nine reviewed cases].

We led a retrospective study to determine the causes of the tendon ruptures post-operating in the surgery of the wrist rheumatoid dorsal and to estimate the clinical result. At follow-up, we measured the extension lag and the rolling-up of fingers by the distance palm-pulps. Nine patients were so revised in the average of 40 months, average age was of 50.7 years. The tendon ruptures arose in 3 months in 67% of the cases. Seven times, a procedure on the distal radio-ulnar joint had been necessary (5 Sauvé-Kapandji and 2 Darrach). Thirty tendons had been concerned in this study, that is 3.3 tendons on average (1-5). Two main causes were found: attrition on the stub ulnaire and great intra-tendinous synovitis (per operating observation). At the revision, the lag extension means was 23 degrees (0-40). Rolling-up of the long fingers was complete 4 times on 7. The best results were observed after tendinous grafting or index proprius transfer with a lateral suture. Tendinous adhesions had arisen 6 times and persisted still at 3 patients. Our study underlines the interest to stabilize the stub ulnaire to prevent the post-operating ruptures and proposes a transfer or a graft in front of tendons very weakened by the synovitis.

Adult↗

[A 36 month prospective study of 12 plate osteosyntheses of distal radius fractures].

INTRODUCTION: We performed a prospective study of 12 intra-articular distal radial fractures. The fractures were treated with an anterior plate together with posterior pinning. The aim of the study was to examine whether it was technically feasible to fix such fractures using this technique and to assess the stability of the fixation at follow up. METHOD: Twelve articular fractures were included with a mean age of 47.1 years. All patients were followed up from first admission to the 36th postop month with clinical and radiological checks. RESULTS: At follow up, we found 8 good and excellent clinical results, 3 fair and 1 poor. The combination of an anterior plate with posterior pinning allowed a good initial reduction but could not protect from secondary displacement particularly in the presence of a comminuted metaphysal fracture. DISCUSSION: This procedure gave clinically satisfactory results but did not control ulnar variance. This procedure should be combined with bone grafting in complex metaphysal fractures and epiphysal screws should be used whenever possible.

Bone Nails↗

[Surgical correction of fifth finger permanent abduction by tenodesis. Preliminary cadaver study].

Permanent abduction of the little finger can be responsible for daily embarrassment in patients with an ulnar nerve palsy. To correct this deformity, active transfers are usually performed utilising the extensor tendons of the hand. Because of the anatomical variability of the extensor system of the hand, these active transfers can be responsible for postoperative loss of full extension of the little finger. Analysis of the orientation of the forces generated by these transfers shows that they are only weak adductors. A surgical technique using tenodesis is proposed in this preliminary study. This tenodesis has the objective of increasing the adductive forces on the little finger without an extensor tendon transfer. The advantages and disadvantages of this technique are discussed. A clinical evaluation will be undertaken at a later date to confirm the reliability of this technique.

Activities of Daily Living↗

[Management of stiffness after total knee arthroplasty: indication for different mobility management in 62 cases].

PURPOSE OF THE STUDY: Stiffness of the knee is a common reason for revision of total knee arthroplasty. Three methods are currently used to mobilize the knee: manipulation under general anesthesia, arthroscopic release, open surgical release. The purpose of the present work was to determine the respective indications of these three procedures in a large single-center study. MATERIAL AND METHODS: We retrospectively assessed all revision procedures without component exchange in patients with a stiff total knee prosthesis. Sixty-two procedures were performed in our institution between 1989 and 2001. All patients were followed for at least one year. There were 34 manipulations under general anesthesia, 18 arthroscopic release procedures, and 10 open surgical release procedures. The three groups were not different for all parameters studied except time interval between implantation of the prosthesis and the mobilization procedure: 17 weeks for manipulation under general anesthesia, 46 weeks for arthroscopic release, 97 weeks for surgical release. A comparable postoperative analgesia and rehabilitation program was instituted for all patients. RESULTS: Range of flexion improved after all 62 procedures: mean 58.4 degrees before the procedure, mean 94.6 degrees at one-year follow-up. Flexion deformity also improved from 7.6 degrees to 2.5 degrees at one year (p=0.001). From surgery to one-year follow-up, there was a decrease in flexion (104.6 degrees to 94.6 degrees ) and an increase in flexion deformity (1.3 degrees to 2.5 degrees ) (NS). The worst postoperative ranges of motion were observed at six weeks after the procedure. Improvement was then observed up to six months but was not significant. There was no improvement in flexion beyond six months after the mobilization procedure. The results of the three techniques were not significantly different. Failures were however more frequent when manipulation under anesthesia was performed more than eight weeks after prosthetic insertion, and when arthroscopic release was performed more than six months after prosthetic insertion (p<0.01). DISCUSSION AND CONCLUSION: We recommend treatment of stiff total knee prosthesis by manipulation under general anesthesis if the procedure is performed less than eight weeks after implantation; a delay of six weeks is even better because intraoperative complications were observed for patients treated between six and eight weeks. Between eight weeks and six months, arthroscopic release should be advised, surgical release thereafter. Whatever the delay, this protocol is appropriate for stiff knee prostheses without infection and without component malposition. Whatever procedure is applied, the definite range of motion is reached six months after the intervention.

Arthroplasty, Replacement, Knee↗

[Effect of anterior and posterior capsule release on elbow joint stability: an experimental study].

PURPOSE OF THE STUDY: The effect of the articular capsule on elbow stability is not well documented. Releasing the capsule might modify results of elbow arthrolysis, especially if it would lead to postoperative instability. The goal of the present study was to address the question in a cadaveric study. MATERIAL AND METHODS: Ten fresh cadaver elbows were studied. Anterior and posterior capsulectomy was performed. Lateral and medial collateral ligaments were preserved. Initially, the same operator tested the elbow joints manually in flexion-extension, valgus-varus, and pronosupination. The same joints were then tested with an experimental machine. RESULTS: Under these experimental conditions, no articular laxity was noticed in the coronal or sagittal planes after anterior and posterior isolated capsular release when the elbow joint was exposed to axial rotation, compression, or traction forces. Elbow laxity was observed only when lateral or medial ligaments were released. DISCUSSION: Anterior and posterior capsulectomy during elbow joint arthrolysis does not produce joint instability when the lateral and medial ligaments are preserved.

Aged↗

Lumbar hernia: anatomical route assessed by computed tomography.

Lumbar hernia is classically described as arising from the superior (Grynfeltt's) lumbar triangle or the inferior (Jean-Louis Petit's) lumbar triangle. The present anatomical study based on a computed tomography examination performed in a patient with lumbar hernia, has led to the suggestion that lumbar hernias cross the lumbar wall through a musculoaponeurotic tunnel, whose deep and superficial openings are the superior and inferior lumbar triangles, respectively.

Aged↗

[Stability of the forearm after resection of the distal ulna and proximal radius in rheumatoid arthritis: report of 11 cases].

Combined resection of radial head and distal ulna could jeopardize the stability and kinematics of the forearm bones. The goals of this retrospective study was to investigate these data after resection of distal ulna and proximal radius in rheumatoid arthritis. Between 1990 and 1998, eleven patients had these bone resections combined with implantation of elbow prostheses (eight Kudo and three GSB III). Wrist surgery consisted in five wrist arthrodeses combined with Darrach procedure, four Sauvé-Kapandji procedures and two isolated Darrach procedures. Mean age at surgery was 58 years and the average follow-up was 40 months. We assessed at follow-up: 1) wrist and elbow pain according to Gschwend; 2) stability of the forearm bones (cubitus valgus angle, impingement of the proximal radial stump with humerus, giving away accident of the ulnar distal stump); 3) wrist and elbow mobility. At follow-up six patients had no pain at the elbow and five had slight occasional pain. At the wrist, five patients had no pain and six slight occasional pain. Elbow motion was increased (from mean 83 degrees [50 degrees-100 degrees] to mean 110 degrees [85 degrees-135 degrees]) excepted in supination which slightly decreased (from mean 3 degrees [40 degrees-90 degrees] to mean 75 degrees [85 degrees-90 degrees]). Mean wrist mobility was impaired because of the five combined radiocarpal arthrodeses. If these five wrist arthrodeses were excluded, the mean ranges of motion were: 10 degrees in flexion, 16 degrees in extension, 2 degrees in radial deviation, 14 degrees in ulnar deviation. At follow-up, no patient had giving away accident of the ulnar distal stump nor impingement between radial stump and humerus in full flexion. Average cubitus valgus was 10 degrees. This study pointed out the predominant effect of the interosseous membrane in stability of the forearm bones.

Adult↗

[Role of external fixators for treatment of humeral fractures: report of 23 cases using Orthofix fixators].

From 1991 to 1998, 23 humeral fractures has been treated using the Orthofix external fixator. Average age of the patient was 42 y and average follow-up 55.5 m. Initial trauma was: 13 traffic accidents, four falls at home, two devastating farming accidents, two sports accidents, one aggression and one gun accident. AO classification was used and location of the fracture was classified using Hackethal classification modified by de la Caffinière. Majority of fractures were located at the one-third distal humerus and the majority was also comminuted. At follow-up, elbow range of motion was 130 degrees, shoulder range of motion 161 degrees, external rotation 69.5 degrees and internal rotation 92.5 degrees. Using the classification of Stewart and Hundley, eight excellent, seven good, three fair and two bad results were obtained. There were no postoperative radial nerve palsy. Two external fixators had to be removed because of pin mobility. Failures were: non union and pin mobility in one patient which has to be reoperated on; two non unions have been grafted on and plated. There were no malunion in the postoperative X-rays. This device is our favourite for this type of injury because of its rigidity and the possibility of secondary dynamization. The external fixator was removed after union: this explains the long delay of union in our series.

Accidents↗

[Kudo non-constrained elbow prosthesis for inflammatory and hemophilic joint disease: analysis in 30 cases].

PURPOSE OF THE STUDY: We analyzed retrospectively 30 Kudo non-constrained elbow prostheses to determine: 1) functional outcome and mobility, 2) frequency of loosening and any complications. MATERIAL AND METHODS: From 1992 to 1998, 30 Kudo total elbow arthroplasties were performed in 29 patients, mean age 55 years. Mean follow-up was 36 months. These patients had severe joint disease: rheumatoid arthritis for 24, psoriatic arthritis for 2, and hemophilic arthritis for 3. The 29 patients experienced severe pain before surgery. RESULTS: At review, 21 elbows were pain free and the 9 others had only occasional pain. Among these 9 elbows, 3 exhibited a rupture of the humeral implant; one had already been revised but remained painful. One patient had a stiff painful elbow after reflex dystrophy and five others had pain but no other complication. Twenty-six patients were satisfied or very satisfied. Three patients were unsatisfied because of the humeral implant fracture. Mean mobility at last follow-up was: 128 degrees flexion, -35 degrees extension, 72 degrees pronation, and 74 degrees supination. Mean gain in flexion-extension was 15 degrees and mean gain in pronosupination was 3 degrees. Pronosupination was greater than 100 degrees except for two patients. There was one immediate post-operative dislocation with failure of prolonged orthopedic treatment after reduction; this patient underwent revision reconstruction with repair of the ulnar collateral ligaments (plasty of the medial collateral ligament with a synthetic ligament). Painful movement of the radial stump was observed with one Kudo prosthesis and required resection to achieve cure. In all, there were 3 fractures of the Kudo I prosthesis at the junction of the trochlea and the humeral stem. Among these patients, one underwent revision due to persistent pain, and two others with currently acceptable symptoms are awaiting revision. At last follow-up, we had: 1 ulnar loosening associated with cortical thinning facing the end of the ulnar implant that had migrated and showed a circular lucent line measuring > 1 mm and progressing; 9 unique ulnar lucent lines measuring<1 mm without progression at the proximal part of the implant (6 at the bone-cement interface and 3 at the bone-implant interface); 3 humeral radiolucent lines (<1 mm without progression) on the distal part of the Kudo II humeral stems corresponding to a zone without surfacing. We also observed 13 cases of incomplete ossification between the humerus and ulna and among these 13, 7 elbows had amplitudes of less than 100 degrees. DISCUSSION AND CONCLUSION: Elbow arthroplasty can restore a painless joint and maintain or improve elbow motion. The procedure is indicated when the joint disease impair daily life activities. Final mobility basically depends on the preoperative mobility. The bone stock remains the greatest problem with these resurfaced prostheses. The GUEPAR elbow prosthesis would appear to be more adapted due to the reconstruction of the trochlea. Resection of the radial head is a source of instability for elbow prostheses and should lead to the design of three-compartment prostheses.

Activities of Daily Living↗

Variations of pelvic anteversion in the lying and standing positions: analysis of 24 control subjects and implications for CT measurement of position of a prosthetic cup.

The position of the acetabular implant plays a dominant role in the displacement of a total hip prosthesis. CT allows precise measurement of the position of the cup, but the influence of pelvic rotation on this measurement is unknown. The aim of this study was to determine, in a group of healthy subjects, whether a pelvic equilibrium exists specific to each individual, and whether this is constant over time on the one hand and between the standing and lying positions on the other. The study concerned 15 men and 9 women with a mean age of 31 years. Each subject had strictly lateral radiographs of the pelvis, lying and standing, repeated at two different times. Pelvic version was measured in these radiographs. Each individual had a pelvic position constant over time, both in the lying and standing positions. However, there were important variations of the position of the pelvis during passage from the lying to the standing position: 22 patients had retroversion of the pelvis by a mean of 7 degrees (2-18 degrees) and 2 others had an anteversion of 3 degrees. These major variations of the pelvic position between the standing and lying positions explain why CT studies made in the lying position do not allow for the anteversion of the cup in the standing position, which is close to the dynamic situation during which displacement may occur. Thus, an excessive anteversion of the cup may be masked when the scan is made in the lying position, since in this position the anteversion of the pelvis leads to retroversion of the cup. The error may reach 20 degrees, so that we recommend that CT measurements made without allowing for the position of the pelvis should be interpreted with caution.

Adult↗

Moral issues in day-to-day palliative medicine and their relevance for the education of European general practitioners.

BACKGROUND: Considerations of moral problems in palliative medicine often deal with extreme situations. This study identified moral issues arising in routine palliative medicine. Their relevance for the education of European general practitioners is assessed. METHODS: Consecutive consultations of cancer patients with incurable disease were recorded in three outpatient clinics and one general practice in Belgium. Moral issues were identified by qualitative analysis of verbal transcripts of 30 of these consultations using the grounded-theory approach. The relevance of these issues for medical education was assessed by interviewing one educator of general practitioners from each of the 15 European Union states. RESULTS: Three core categories of moral issues were identified: telling the truth, patient control versus medical dominance, and handling the patient's life-world. The practical relevance of these issues was recognized by the educators. The suggested educational methods to deal with these topics were all active learning processes in small-group settings but varied otherwise. CONCLUSIONS: The moral issues identified in day-to-day palliative medicine may complement the problems evoked in the literature dealing with more extreme situations. An effort to study the appropriate way for medical education to deal with these topics may be indicated.

Europe↗

[Decompensation of lower limb arteritis after bone and joint surgery].

PURPOSE OF THE STUDY: Decompensation of lower limb arteritis after bone and joint surgery is an unusual finding compared with the large number of procedures performed in both emergency and controlled settings. There is however a functional and limb-threatening risk that must not be overlooked. MATERIAL AND METHODS: We report a series of 9 patients followed in our department over the last 3 years. Emergency surgery had been required in 6 patients after trauma and 3 had undergone a planned orthopedic procedure. All the patients had at least one vascular risk factor, and 7 of them had a cardiovascular history. The inaugural sign was a trophic disorder due to a grade IV decompensated arteritis in 8 patients, including 2 with nonunion. Delay to treatment ranged from 1 to 3 months. Acute embolic ischemia required emergency care in 1 patient. RESULTS: A revascularization procedure was performed on 6 limbs and was successful in 3. There were also 6 amputations, three initially, 1 after septic shock and 2 because revascularization was impossible. Three of the amputations were required after failed revascularization. Prosthesis wearing and walking was possible in only two amputated patients. Overall rate of successful salvage was 33% (3 successful revascularizations among 9 limbs). One of the nonunions healed after revascularization; the limb was amputated for the other one. One patient died from septicemia. DISCUSSION: Our series further illustrates the severity of decompensated arteritis after bone and joint surgery, emphasizing the importance of searching for cardiovascular risk factors and functional signs suggestive of a vascular disorder. Arterial duplex Doppler and if necessary arteriography of the lower limbs should be obtained in case of doubt. Two different situations can be distinguished depending on the predictable vascular risk and the localization of the planned bone reconstruction. If the patient has an asymptomatic proximal arteritis and bone and joint surgery is planned above the knee, a revascularization procedure would not appear necessary prior to bone surgery. In other cases, it may be more advisable to treat the arteritis before attempting bone surgery. For trauma victims, the osteosynthesis technique depends greatly on knowledge of the vascular risk.

Aged↗

Study by (23)Na-NMR, (1)H-NMR, and ultraviolet spectroscopy of the thermal stability of an 11-basepair oligonucleotide.

23Na-NMR, (1)H-NMR, and ultraviolet (UV) spectroscopy have been used to study the thermal stability of the double helix structure of an 11-basepair oligonucleotide. The denaturation curves obtained by (23)Na-NMR and UV are analyzed using a two-state model. The melting temperature and DeltaH(0) obtained are identical within experimental error, suggesting that modifications in the ionic atmosphere, probed by (23)Na-NMR, and the modifications in the basepair stacking, probed by UV, occur at the same temperature. Additional dynamical information on the denaturation process has been obtained by (1)H-NMR: slow exchange is observed between the thymine methyl resonances, and the disappearance of imino protons shows that a single basepair opening does not contribute significantly to proton exchange.

Base Pairing↗

Effect of the Steindler procedure on the median nerve branches to the medial epicondylar muscles.

Usually the median nerve gives off six branches to the muscles arising from the medial epicondyle, which could be tightened during Steindler's procedure. We studied these branches before and after Steindler's procedure in 20 fresh cadavers and observed a considerable variation in the origin of the branches. The muscular branches arising from the median nerve did not seem to limit the mobilization of the medial epicondyle when performing Steindler's transfer. The limitation of the flexion observed after Steindler's procedure was mainly related to the tension of the transferred forearm flexor muscles. The variability of the origin of the branch to the flexor digitorum superficialis muscle could explain a lesion of this branch when Steindler's procedure is carried out with Brunelli's modification. The lateral transfer and the anterior transfer on to the humeral shaft did not influence the limitation of elbow flexion or result in tightness in any nerve branch to the transferred muscles.

Humans↗