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Biomedical subjects

C Fisch

Publications and source records attributed to C Fisch.

At least 73 records · Page 4Linked to original sources
PubMed1985

Effect of fluoxetine on the electrocardiogram.

The effects of fluoxetine on the ECG were compared to those of placebo, imipramine, amitriptyline, and doxepin. ECG tracings at the beginning and end of several drug studies were evaluated retrospectively, without knowledge of the drug to which patients had been assigned. Mean changes in heart rate revealed a statistically significant decrease in the fluoxetine group. Active control drugs increased heart rate: increases were significant for imipramine and amitriptyline but not doxepin. Intraventricular conduction delays were noted in 5 patients who received imipramine and 1 patient who received amitriptyline: 4 of these patients developed left bundle branch block. No intraventricular conduction delays were noted in fluoxetine-treated patients.

Adult↗
PubMed1985

The vitamin status of infants in a free living population.

In infancy an adequate intake of vitamins, either from natural sources or as supplements, is of the utmost importance. The vitamin status of 325 infants was studied with regard to their food intake, vitamin supplementation and health from birth to the third birthday. Only data on vitamins A, C, E and folic acid are presented here. The proportion of bottle-fed infants having a serum level of vitamin C less than 0.30 mg/dl was 4.0 times (P less than 0.002), and of vitamin E less than 0.35 mg/dl was 2.2 times (P less than 0.05) higher than that of breast-fed infants. The proportion of infants with folate level less than 6.0 ng/ml was identical in both groups. No infant was observed with a vitamin A serum level less than 40 mcg/dl. The daily food intake of vitamin C less than 80% of RNI was found n 40% of infants at 6 months, in 10% at 12, and in none at 18 months and afterwards. Vitamin A followed a similar trend. 95% of infants had vitamin E and 75% had folate intake less than 80% RNI. Obviously the mean serum levels of vitamins A and C were significantly higher in supplemented infants at 6, 12, 18 and 30 months than in those without supplements. Health indicators, measured by number of self-reported illness related symptoms, differed according to supplementation. These findings indicated that, even if optimal food intake could supply the recommended quantity of vitamins, the risk of marginal deficiency always remained higher in infants without supplementation.

Age Factors↗
PubMed1984

Radiologically visible fecal gas patterns in "normal" newborns and young infants.

A prospective study of abdominal and chest films of 212 babies without symptoms of intra-abdominal disease, aged 1 day-12 weeks, showed that the bubbly "fecal pattern" normally seen in older children is rare in young premature babies in the first two weeks of life. When it is seen, it may represent intramural air bubbles and signal the presence of necrotizing enterocolitis.

Colon↗
PubMed1983

Electrocardiography of arrhythmias: from deductive analysis to laboratory confirmation--twenty-five years of progress.

Before the advent of the microelectrode, His bundle recording and direct cardiac pacing, electrocardiographic interpretation of arrhythmias in human beings was based on presumed mechanisms derived by deductive analysis. This indirect approach was forced by the fact that the surface electrocardiogram does not directly record the behavior of the specialized tissue that is the site of origin of most arrhythmias. In the past 25 years it has become possible to record directly from the specialized tissue. The result has been experimental confirmation of several underlying concepts of the electrocardiographic interpretation of arrhythmias and progress evidenced by the conversion of concept to fact.

Arrhythmias, Cardiac↗
PubMed1983

Concealed conduction.

To analyze all but the most simple of cardiac arrhythmias, one must understand the concept of concealed conduction. The numerous electrocardiographic manifestations of concealed conduction, some illustrated in this discussion, remain interesting models of basic electrophysiologic phenomena.

Arrhythmias, Cardiac↗
PubMed1982

Biochemical indices of nutritional status in maternal, cord, and early neonatal blood.

The nutritional status of 556 infants born in good health was measured by selected biochemical parameters in maternal venous blood, in mixed arteriovenous cord blood at delivery, and in infant's capillary blood collected at 5 days. The determinations indicating nutritional status were: Hb, hematocrit, protein, cholesterol, triglycerides, vitamins A, C, E, and folic acid, iron, calcium and magnesium. In maternal venous blood, a significant number of women were found to be deficient; 3.4% had Hb below 9.5 g/dl; 6.1% had hematocrit less than 30%; 4.0% had total protein below 5.5 g/dl; 7.0% had vitamin C below 0.20 mg/dl; 3.0% were deficient in iron (less than 40 microgram/dl), 3.6% in folic acid (less than 2.0 ng/ml) and 5.2% in calcium (less than 7.5 mg/dl). Significant correlations were more frequent between maternal and cord blood than in other comparisons. An influence of parity and maternal age was more evident for vitamin C in cord blood than in maternal venous blood. Iron in maternal and cord blood decreased in relation to parity.

Adolescent↗
PubMed1981

The electrocardiogram in the aged.

A review of the electrocardiogram in the aged and the comparison of prevalence of ECG abnormalities in the young and aged suggest that: 1. The same criteria for normal ECG should be applied to both groups. Some minor changes in advancing age can be accepted as normal and reflecting physiologic changes attending growth, changes in anteroposterior diameter of the chest and lung volume, and so on. 2. The abnormal ECG is most likely a marker of anatomic heart disease or clinical heart disease, or both. 3. The incidence of abnormal electrocardiograms increases with age and heart disease. 4. The specific ECG abnormalities which have a high degree of correlation with clinically evident heart disease include atrial fibrillation, left bundle branch block, intraventricular conduction defects, and ST segment and T wave changes. 5. Myocardial infarction, left anterior hemiblock and right bundle branch block did not correlate with presence of clinical disease, but strong evidence suggests that these findings reflect anatomic disease.

Adult↗