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Biomedical subjects

C Faschinger

Publications and source records attributed to C Faschinger.

At least 37 records · Page 2Linked to original sources

[Initial description of a retinal ganglioglioma].

Gangliogliomas are very rare neuronal tumors, predominantly localized in the thalamus, third ventricle, and temporal lobe. They usually occur in younger patients, grow slowly, and their glial components may develop to malignancy. A case is reported in which a tumor was detected on the upper rim of the optic disk. The patient was then four years old. Five years later the eye hat to be enucleated because of increasing growth and vascularization of the tumor. Histologically, it consisted of mature ganglion cells and neoplastic glial cells. Six years later, in addition to the glial hamartoma, a vascular hamartoma, i.e., a hemangioblastoma of the cerebellum, was found, this tumor was extirpated.

Biomarkers, Tumor↗

[Limbus-based flap versus fornix-based flap in goniotrepanation].

In a prospective, randomized study 61 eyes in which goniotrepanation had been performed using fornix-based or limbus-based conjunctival flaps were followed up for 4 to 18 months. No differences were found in the results of filtration, nor in the form and frequency of filtering blebs or the frequency of complications. In view of the easier technique and better visualization, the present authors prefer the fornix-based flap.

Adult↗

[Visual fixation tonometry as an aid in the early diagnosis of endocrine ophthalmopathy].

In some cases of autoimmunogenic hyperthyroidism an endocrine ophthalmopathy is found, but it is difficult to diagnose Graves' disease in early stages. Even before the occurrence of measurable morphological changes (measured by sonography and computed tomography of the orbit and eye muscles) short positional intraocular pressure changes are found in 64.5% of cases with autoimmunogenic dysthyreosis. These pressure changes are detected by positional applanation tonometry. These findings admit the conclusion that with the method described not only early detection of ocular signs associated with thyroid disease is possible, but also early differentiation between autoimmunogenic and nonimmunogenic thyroid disorders.

Eye Movements↗

[Follow-up of children after toxoplasmosis infection in pregnancy].

A vival toxoplasmosis infection was diagnosed in 188 cases (3,8%) out, of 49,582 pregnant women routinely screened. 4 children live with congenital toxoplasmosis. Follow-up studies showed that 33 children have specific antibodies, 5 are with suspect clinical findings. Therefore is the conclusion that more late signs of connatal toxoplasmosis are to be detected by follow-up investigations.

Antibodies↗

[HbA1 as a parameter of the progression of diabetic retinopathy].

HbA1 was determined in 12 juvenile diabetics with diabetic retinopathy and in ten adult diabetics at four-weekly intervals. During this time the course of the retinopathy was observed. Retinopathy was constant in juvenile diabetics with HbA1 values below 8%. A moderate progression, which it was possible to slow down by laser treatment, was observed in patients with HbA1 values of between 8% and 10%. Patients with HbA1 values exceeding 10% showed a marked progression, which could not be stopped by intensive laser therapy. The behavior of the retinopathy in adult diabetics corresponded to that of the juveniles when the onset of the disease was between the ages of 30 and 50. In elderly diabetics no significant tendency was observed.

Adult↗

[Visual field examinations using the Octopus computerized perimeter following laser therapy of central serous chorioretinitis (Wessing type I)].

The authors examined 19 patients who were suffering from central serous chorioretinopathy were treated with argon laser beams with a special user-defined program of the Octopus computerized perimeter. Relative scotomata were found at a depth of between 4 and 10 decibels in 66 percent of the patients; they were seldom subjectively considered to be a disturbance.

Adult↗

[Partial canaliculus transplantation (author's transl)].

In some cases of palpebral tumors, causing epiphora by canalicular obstruction, surgical reconstruction of the lacrimal system is necessary . The defect of the nasal part of the lower lid is closed by transplantation of the nasal part of the upper lid of the other eye, including a part of the canaliculus. Three patients suffering from basaliomas in the region of the lower canaliculus were treated by this method. Good cosmetic and functional results were achieved.

Aged↗

[Diagnosis and differential diagnosis of hysteric amblyopia using psychophysical and electro-ophthalmological examination methods (author's transl)].

In three patients with psychogenic amblyopia the computerized visual field, the ERG, the flash light (H-EP) and pattern reversal stimulated (M-EP) cortical potentials were recorded. Differential diagnosis between psychogenic amblyopia on the one hand, and functional amblyopia and organic lesions of the retrobulbar visual pathways on the other was shown to be possible. In the cases with organic retrobulbar lesions of visual pathways, visual field defects and pathologic H-EP's and M-EP's were found. In functional amblyopia only the M-EP responses are diminished in amplitude. In psychogenic amblyopia only the computerized visual field shows pathologic changes.

Adolescent↗

[Electro-ophthalmological responses in inflammations of various sections of the orbital visual pathways (author's transl)].

In a study of electro-ophthalmological responses of the EOG, the photopic and scotopic ERG, the OP and the VECP, in combination with fluorescein angiography and computerized perimetry, in 34 patients suffering from uveitis, chorioretinitis (lesions near the macula and at the periphery), papillitis or retrobulbar neuritis, the following results were obtained: Uveitis and chorioretinitis with lesions either near the macula or at the retinal periphery produce different responses; generally, pathologic responses of the EOG and ERG and normal VECP are obtained in cases of uveitis. Peripheral chorioretinal lesions lead to a diminution of the scotopic ERG, OP and EOG, in contrast to lesions near the macula, in which pathologically diminished amplitudes of the photopic ERG and VECP are found. In papillitis and retrobulbar neuritis, however, the most important peculiarity is the increase in latency and the decrease in amplitudes of the VECP, especially in retrobulbar neuritis.

Chorioretinitis↗