The lectin content of some native plants in Taiwan was studied. The majority of the plants possessing lectin belonged to Leguminosae. Five lectins which are readily available were further studied for their hemagglutination titers, specificity, susceptibility to heat and proteolytic enzymes. The lectins of Ricinus communis had hemagglutination titer of 1:512 which was the highest among the five tested. All lectins were heat labile, destroyed by heating at 100 degrees C for 30 min, but resistant to trypsin and pepsin. The resistance was not due to the presence of any inhibitor in the crude extract, but possibly due to the special configuration of the lectin molecule or other unknow reasons. Among the five lectins only the lectin of Phaseolus vulgaris could not be inhibited by any of the carbohydrates tested. It seems that the lectin of Phaseolus vulgaris is nonspecific, or not specific for ABO blood group, or specific for other blood groups. The inhibiting activity of carbohydrates seems to be specific. The configuration of carbohydrates at carbon atom 2 and/or 4, the type of linkage (alpha or beta), or the carbon number where the linkage is formed seem to be important to the potency of carbohydrates to inhibit the activity of lectin.

Carbohydrates↗

PubMed1967

Correlations of nuclear magnetic resonance and optical rotatory dispersion spectra for establishing the absolute configurational assignment of cobalt(3)-chelated optically active triethylenetetramine homolog-alpha-amino acid adducts.

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Alanine↗

PubMedDate not supplied

Preoperative correlates of the cost of coronary artery bypass graft surgery: comparison of results from three hospitals.

This article furthers our understanding of the cost of coronary artery bypass graft (CABG) surgery by analyzing the extent to which preoperative correlates of cost differ among hospitals. A total of 2828 patient who underwent bypass surgery at 3 hospitals (2 teaching and 1 nonteaching) were analyzed. The preoperative correlates of direct variable cost (marginal cost) were determined by ordinary least squares regression. Age, urgent/emergent surgical priority, previous CABG, and chronic obstructive pulmonary disease (COPD) were significant contributors (P < .05) to cost in all hospitals, but overall, there were many differences. The major contributor to cost was non-white race (31.3%) at teaching hospital A, previous CABG (30.5%) at teaching hospital B, and preop insertion of intra-aortic balloon pump (IABP) (35.9%) at the nonteaching hospital. The number of significant risk factors also differed. Preoperative characteristics that contribute to cost can be quite different among hospitals and therefore results from one hospital cannot be broadly generalized to others.

Age Factors↗