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Biomedical subjects

C F Kramer

Publications and source records attributed to C F Kramer.

6 recordsLinked to original sources
PubMed1995

The prevalence of age-related maculopathy in the Rotterdam Study.

PURPOSE: To determine the prevalence of age-related maculopathy in an elderly population in The Netherlands. METHODS: Fundus photographs of 6251 participants of the Rotterdam Study, a single-center prospective follow-up study in persons 55 to 98 years of age, were reviewed for the presence of drusen, pigmentary abnormalities, and atrophic or neovascular age-related macular degeneration. RESULTS: The prevalence of at least one drusen of 63 microns or larger increased from 40.8% in persons 55 to 64 years of age to 52.6% in those 85 years of age or older. Similarly, the prevalence of the following abnormalities increased significantly in these age categories: drusen of 125 microns or larger from 4.8% to 17.5%, retinal pigment epithelial hypopigmentations from 3.5% to 9.0%, and increased retinal pigment from 3.7% to 15.3%. Atrophic or neovascular age-related macular degeneration was present in 1.7% of the total population. Atrophic age-related macular degeneration increased from 0.1% in persons 55 to 64 years of age to 3.7% in those 85 years of age or older. Neovascular age-related macular degeneration increased from 0.1% to 7.4% in these age groups. No sex differences were observed for these lesions. CONCLUSIONS: The prevalence of atrophic or neovascular age-related macular degeneration is 1.7%. In those 55 years of age or older, the prevalence increases strongly with age and it is similar in men and women. Neovascular age-related macular degeneration was twice as common as atrophic age-related macular degeneration. These findings suggest that age-related maculopathy may be less common in this European population than in similar populations in the United States.

Aged↗
PubMed1995

Adequacy of hospital discharge data for determining trauma morbidity patterns.

To determine the adequacy of hospital discharge data for describing the nature and severity of multiple trauma, injury data coded from full hospital records were compared with injury data coded from discharge summaries for 83 plane crash survivors admitted to 14 different hospitals. Full hospital records indicated that 33% sustained intracranial, 39% thoracic, and 27% abdominal/pelvic injuries. Thirty-five percent had spinal fractures, 40% upper limb fractures, and 70% lower limb fractures. Discharge summary data missed 52% of the intracranial injuries, 28% of the thoracic injuries, and 30% of the spinal fractures, yet only missed 5% of the lower limb and 15% of the skull, pelvic, and upper limb fractures. These differences point to concerns regarding the use of discharge data for determining the nature, severity, and sequelae of injuries. The observed underreporting of neurological injury suggests a need to re-evaluate discharge data systems for measuring brain and spinal cord injury patterns, particularly given the increasing reliance on these systems for health policy and programmatic decision making.

Hospital Records↗
PubMed1986

Motor vehicle trauma in northeastern Ohio. I: Incidence and outcome by age, sex, and road-use category.

Hospital emergency department visits for motor vehicle trauma occurring in a midwestern metropolitan region (Cleveland and Lorain-Elyria, Ohio Standard Metropolitan Statistical Areas; 2.2 million population) were analyzed to determine the incidence and outcome by age, sex, and road-use category. A 50% incidence sample (n = 20,752) of motor vehicle trauma events to residents of this region was identified from the emergency department records of 41 participating hospitals for a one-year period, 1977. These hospitals accounted for 98% of all emergency department cases in the region. The annual motor vehicle trauma incidence rate per 100,000 population was 1,871. The highest annual incidence rate (4,462) was for ages 20-24; the lowest rates were for infants under one year (837) and for the elderly over 74 years (667). Incidence rate rank-ordered road-use categories were as follows: passenger car occupant, motorized cycle rider, other enclosed vehicle occupant, pedestrian, and pedal cyclist. Above age 4, age-specific male incidence rates significantly exceeded female incidence rates for most road-use categories. There were 80 admissions and 7 fatalities per 1,000 motor vehicle trauma incidence cases. Case-admission ratios were highest for pedestrians (266), riders of motorized cycles (184), and pedal cyclists (115); they were lowest for occupants of partially or fully enclosed vehicles (65). Case-fatality ratios per 1,000 cases were also highest for pedestrians (43) and riders of motorized cycles (11). Male case-fatality ratios exceeded female ratios for each road-use category in nearly all age groups, and male case-admission ratios exceeded those for females ages 10-54. For ages 75 and over, the admission ratios and fatality ratios were nearly twice as high as in any other age group.

Accidents, Traffic↗
PubMed1968

Puerperal shock.

Explore the source record for details and available documents.

Female↗
PubMedDate not supplied

Improving the sensitivity and specificity of the abbreviated injury scale coding system.

The Abbreviated Injury Scale with Epidemiologic Modifications (AIS 85-EM) was developed to make it possible to code information about anatomic injury types and locations that, although generally available from medical records, is not codable under the standard Abbreviated Injury Scale, published by the American Association for Automotive Medicine in 1985 (AIS 85). In a population-based sample of 3,223 motor vehicle trauma cases, 68 percent of the patients had one or more injuries that were coded to the AIS 85 body region nonspecific category external. When the same patients' injuries were coded using the AIS 85-EM coding procedure, only 15 percent of the patients had injuries that could not be coded to a specific body region. With AIS 85-EM, the proportion of codable head injury cases increased from 16 percent to 37 percent, thereby improving the potential for identifying cases with head and threshold brain injury. The data suggest that body region coding of all injuries is necessary to draw valid and reliable conclusions about changes in injury patterns and their sequelae. The increased specificity of body region coding improves assessments of the efficacy of injury intervention strategies and countermeasure programs using epidemiologic methodology.

Accidents, Traffic↗