Familial steatorrhoea with calcification of the basal ganglia and mental retardation.
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Biomedical subjects
Publications and source records attributed to C F Hawkins.
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The xylose test was used to assess the effect of drugs on intestinal absorption. Both aspirin and indomethacin reduced the urinary output of xylose. By giving xylose intravenously as well as orally it was found that aspirin had a parenteral effect, probably impairing renal function, whereas indomethacin depressed intestinal absorption.
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One hundred and sixty-three patients who had been diagnosed as suffering from diarrhoea without an organic cause were followed up to assess the risk of missing malignant disease. Three patients with carcinoma, two involving the stomach and one the colon had escaped diagnosis and the reasons for this are given. Prognosis in the others was usually good.
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One hundred patients were examined with the Olympus GTF-A fibregastroscope and gastrocamera. The entire stomach was seen in most cases; the technique permitting this is described in detail. The examination was most rewarding in patients with gastric haemorrhage and when radiology was equivocal. Advantages and disadvantages of the instrument are discussed.
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