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Biomedical subjects

C Evian

Publications and source records attributed to C Evian.

16 recordsLinked to original sources
PubMed1991

Knowledge and attitudes relating to condoms on the part of African high school children around Johannesburg.

Senior high school children completed a self-administered questionnaire on sexual activity, knowledge of family planning methods, condoms and use of condoms. The study highlighted some useful and interesting information though its value is limited by a poor response rate. The results suggest that at least 50% of the scholars are sexually active, but only about 20% reported sexual intercourse during the month preceding the survey. This small group reports more than 1 sexual partner and unprotected sexual intercourse in over 50% of the cases. Knowledge of condoms was poor and a number of factors relating to resistance to condoms are identified. These must be addressed by a combination of social marketing and educational strategies. The most important finding is that half of the children were still not sexually active. Education programmes therefore should support the development of safe and responsible sexual lifestyles.

Adolescent↗
PubMed1981

Serum neutralizing activity against Actinobacillus actinomycetemcomitans leukotoxin in juvenile periodontitis.

A relatively high incidence of infection by Actinobacillus actionomycetemcomitans can be shown in subgingival plaque samples obtained from patients with juvenile periodontitis. These organisms possess a potent leukotoxin(s) which rapidly destroys isolated human polymorphonuclear leukocytes (PMNs) and monocytes. If such leukotoxins operate in vivo, they could deprive the gingival crevice area of an essential antibacterial defense mechanism. We have found that sera from juvenile periodontitis patients consistently (greater than 90%) contain antibodies which neutralize Actinobacillus actinomycetemcomitans leukotoxin(s). On the other hand, sera from normal individuals or patients with other types of periodontal disease usually amplified rather than inhibited the leukotoxic reaction. Many patients with juvenile periodontitis have demonstrable defects in PMN or monocyte chemotaxis and this may place them at risk to gingival infection by Actinobacillus actinomycetemcomitans. The immune response against these organisms could be a crucial determinant in the course of juvenile periodontitis. While this disease is relatively rare, it does cause immeasurable emotional, physical and economic hardship for patients and their families. The identification of Actinobacillus actinomycetemcomitans as a potential pathogen in this disorder may eventually lead to specific forms of therapy to prevent and eliminate infection by this organism in these patients.

Actinobacillus↗
PubMedDate not supplied

AIDS in South Africa.

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AIDS Serodiagnosis↗