White House Conference on Aging.
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Biomedical subjects
Publications and source records attributed to C Eisdorfer.
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Diastolic hypertension was related to significant intellectual loss over a 10-year period among individuals initially examined in their 60's. Such loss was not found in their age peers in association with normal or mild elevations of blood pressure. Of the subjects initially examined at 70 to 79 years of age, none with hypertension completed the follow-up program, and those with normal and mildly elevated blood pressure showed some intellectual decline over the decade. At the initial examination, hypertension was related to lower intelligence test scores only among those subjects who subsequently did not complete the follow-up program. The results suggest that hypertension is related to intellectual changes among the aged.
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Partial blockade of beta-adrenergic end-organ response to the autonomic nervous system was effected in a group of older men by administration of propranolol. The result was improved performance in a learning task. The data support the hypothesis that the learning decrement found among older men is not simply a manifestation of structural change in the central nervous system but is, at least in part, associated with the heightened arousal of the autonomic nervous system that accompanies the learning task.
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