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Biomedical subjects

C Eckardt

Publications and source records attributed to C Eckardt.

At least 55 records · Page 3Linked to original sources

[Bilateral traction detachment in necrotizing retinitis as a sequela of toxoplasmosis].

A 35-year-old patient with systemic lupus erythematodes is presented. Two weeks after initiation of an immunosuppressive therapy with steroids and cyclophosphamide she developed a bilateral acute necrotising retinitis. Although the infiltration of the vitreous body was only slight the right eye developed a traction retinal detachment within a few days. A vitrectomy was performed but the situation was found to be inoperable due to central necrotic areas. Two days later serological specimen revealed an acute toxoplasmosis as the cause of the bilateral retinitis in this patient. A therapy with sulfadiazine and pyrimethamine was started immediately. Nevertheless two weeks later traction retinal detachment occurred also in the left eye. A reattachment of the retina could be achieved by vitreoretinal surgery.

Adult↗

[Visual acuity and binocular vision following surgery of extreme retinal detachment].

Retinal surgery with implantation of silicone oil was performed in 33 patients presenting with idiopathic or traumatic proliferative vitreoretinopathy. Following removal of the oil patients were on average followed-up for 6 to 29 months (14 months). Sixteen patients had had buckling procedures prior to endosurgery. Improvement of vision up to 4 rows of optotypes was noted in 21 patients following silicone oil removal. Three cases showed a large, organic, central scotoma. Ten patients suffered from diplopia; 3 of whom were known to have had a preexisting strabismus. Suppression of the visual impression of the operated eye was seen in 4 cases. Eye muscle surgery was necessary in 4 cases. Sixteen patients demonstrated normal binocular vision as far as possible taking the visual acuity into account.

Adolescent↗

[Preoperative disinfection of the conjunctiva with PVP-iodine].

Preoperative treatment with topically applied antibiotics does not always sufficiently reduce the bacterial flora of the conjunctival sac. Therefore, an additional disinfection procedure should be employed. Fifty-two eyes showing bacterial growth in the first conjunctical smear were treated with two drops of half-strength povidone-iodine solution (5%). Within 2 min 45 eyes showed an obvious reduction in bacteria; after an incubation time of 48 h, 26 eyes showed no bacterial growth at all. The colony counts of the remaining smears revealed a decrease factor of between 10 and 10(4). The average number of species was reduced from 2.15 to 0.63. To exclude the possibility that this was merely an irrigation effect caused by the povidone-iodine solution, 30 eyes were treated with two drops of NaCl solution and compared to the other groups. No significant decrease in colonies or species was observed. Povidone-iodine solution applied to more than 500 eyes undergoing vitreoretinal surgery caused no allergic reactions or corneal changes.

Cataract Extraction↗

[Posterior uveitis caused by highly malignant B cell lymphoma].

A diagnostic vitrectomy was performed on three patients with posterior uveitis of unknown origin and whose vitrous body was markedly affected. In all cases, cells of high-grade B-cell lymphoma (earlier referred to as reticulum cell sarcoma) were identified by cytological analysis of the specimen. In addition to the ocular findings, one of the three patients showed clinical and radiological evidence of a tumorous mass in the area of the right thalamus at the time of diagnosis. This was interpreted as a cerebral manifestation of the lymphoma. Initially, the other two patients did not show any cerebral involvement. One of them, however, developed clinical symptoms 9 months after diagnosis, which were radiologically verified as tumor infiltration of the cerebellum and the diencephalon. Under radiation therapy, the ocular findings disappeared within a few weeks.

Adult↗

Modified temporary keratoprosthesis in the triple procedure: a new surgical technique.

We present a new surgical technique for use in the triple procedure. After trephining the cornea, we sutured a temporary keratoprosthesis made of silicone rubber into the corneal bed. The prosthesis provided a clear view with excellent depth of focus. By creating an artificial anterior chamber, the operative procedure resembled a normal extracapsular cataract extraction procedure. The keratoprosthesis made complete aspiration of all cortical material easier.

Cataract Extraction↗

[A new temporary keratoprosthesis].

A new keratoprosthesis made of silicone rubber has been developed. It permits pars plana vitrectomy to be performed in eyes with corneal opacities.

Contact Lenses↗

A modified technique of pupillary stretching.

In eyes undergoing vitreoretinal surgery up to now dilatation of a miotic pupil by the pupillary stretching technique could be performed only in aphakic eyes. Now a new needle with a tiny eye at its tip has been developed. With the help of this needle, 4 iris loop sutures can be led around the iris only passing the anterior chamber. This permits pupillary stretching also in phakic eyes. The modified technique was used on 3 phakic and 2 aphakic eyes.

Adult↗

A new temporary keratoprosthesis for pars plana vitrectomy.

Using a new temporary keratoprosthesis in an eye with an opaque cornea and a proliferative vitreoretinopathy, a pars plana vitrectomy combined with a silicone oil injection was successfully performed. The new keratoprosthesis is made of silicone rubber and is fixed to the threphined corneal bed with four 10-0 nylon sutures. It permits an excellent view of the intraocular structures and allows vitreoretinal surgery even in the region of the pars plana and vitreous base. It is replaced by a corneal graft at the end of the vitrectomy.

Adult↗

[Surgical pupillary dilatation within the scope of complicated retinal detachment surgery].

During vitreoretinal surgery 14 aphakic patients with complicated retinal detachment were treated with 2 new techniques for surgical dilatation of a miotic and rigid pupil. In 4 cases, iris excision was not performed in the upper part of the pars pupillaris, as usual, but in the lower part. As a result, peripheral anterior synechiae due to silicone oil injection did not occur postoperatively. In the other 10 cases the pupil was temporarily stretched during the operation with 4 iris loop sutures. These sutures were laid in such a way that a retraction of the iris in the main directions of the 4 quadrants was made possible, thereby forming a large square pupil. Postoperatively, no iris damage was found in those cases where miosis had only developed during surgery. In the case of a preoperatively miotic and rigid pupil, stretching caused multiple small sphincter tears in most cases. A few weeks after surgery these patients again showed constriction of the pupil. Their pupils reacted to light, miotics, and mydriatics, but reactions were diminished.

Diabetic Retinopathy↗

[Endosurgery of subretinal strands in proliferative vitreoretinopathy].

Subretinal strands were removed in 9 patients with retinal detachment complicated by proliferative vitreoretinopathy (Stages C 2 to D 1). A small retinotomy was made in the area of the strand. The subretinal proliferative tissue was then drawn to the surface with forceps. In this way it was possible to remove all of the strands completely. One strand snapped while being drawn, thus necessitating a further incision. Two additional small retinectomies had to be performed because of firm attachments to the retina. In all cases retinal reattachment was achieved by silicone oil injection. No postoperative recurrences of the proliferations were observed. The follow-up period ranged from 2 to 9 months.

Adult↗

[Effects of locally administered corticosteroids on mineral metabolism].

The author performed a prospective study to test the mineralocorticoid activity of high doses of topically applied corticosteroids. Eight patients were treated with prednisolone eye drops. Twelve patients received fluorhydrocortisone, 9 patients triamcinolone acetonide and 11 dexamethasone; subconjunctival or parabulbar injections were used in all cases. Only the patients treated with fluorhydrocortisone showed a mineralocorticoid effect, i.e., reduced sodium excretion and a high potassium waste in the urine together with a decrease in serum potassium. Fluorhydrocortisone must not be applied topically because the risk of hypokalemia involved is so great.

Administration, Topical↗

[Transscleral magnetic fixation of the retina in complicated retinal detachment. A preliminary report of our experiences].

The authors describe a new technique for transscleral fixation of a detached retina. A small metal pin is brought into contact with the surface of the retina and is held in position by an extraocular magnet. This technique has been used successfully on three patients with giant tears and with large retinotomies as a preparation for silicone oil injection. In comparison with other fixation methods it was found to be relatively easy, and the incidence of trauma was low.

Humans↗

[Life expectancy of patients with circulatory disorders of the posterior eyeball segment].

Based on the method of person-years, the morality rate of 155 patients with circulatory disorders was calculated and compared with the death rate of an age-matched general population. No excess mortality was found among 53 patients with central retinal vein occlusion and among 58 patients with ischemic optic neuropathy. On the other hand, 44 patients with central retinal or branch artery occlusion showed a statistically significant increased mortality rate. Patients with arterial circulatory disorders were subdivided into hypertensives and normotensives; an increased mortality rate was seen only among patients with hypertension but not among patients with normal blood pressure. Hypertension is one of the main cardiovascular risk factors. The increased mortality risk among our patients with hypertension may be indicative of a progressive atherosclerosis.

Adult↗

[Rare form of ocular involvement in relapsing polychondritis (author's transl)].

Report on a 56-year-old woman with relapsing polychondritis, with ocular involvement in the form of bilateral optic atrophy and paresis of the extraocular muscles. The cause of this disorder has not yet been identified, although it is presumed to be an immune disease. Clinically there are some obvious similarities to systemic vasculitis.

Diagnosis, Differential↗

The taxonomy of Penicillium species from fermented cheeses.

The taxonomy of the Penicillium camberti and P. roqueforti series is re-investigated. P. caseicolum Bainier is regarded as a synonym of P. camemberti Thom on the basis of morphological characters. P. casei Staub is considered to be identical with P. verrucosm Dierckx var. cyclopium (Westling) Samson, Stolk et Hadlok. Descriptions and illustrations of P. camemberti and P. roqueforti Thom are given. The occurrence and mycotoxin production of both species are shortly discussed.

Cheese↗