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Biomedical subjects

C E Thompson

Publications and source records attributed to C E Thompson.

At least 37 records · Page 2Linked to original sources

Transition of the disabled adolescent to adulthood.

Disabled teenagers have problems making the transition from adolescence to adulthood. Helping parents, particularly mothers, 'let go' is an important part of the medical management, as is coordinating the complex medical, social, and educational aspects. Issues of bowel and bladder care, sexuality, dating, dressing, and driving must be considered. Role modeling by successful disabled adults and counseling assist in successful transition.

Adolescent↗

Endocrine, estrous and pregnancy response to varying dosages of Luprostiol in beef cows.

Multiparous lactating beef cows were observed for estrus and randomly assigned to one of four Luprostiol (13, thia-PG-F(2)alpha analog) treatment groups receiving 3.8 (LI), 7.5 (LII), 15 (LIII) or 30 (LIV) mg Luprostiol, respectively, or to an untreated control group (C), or to a positive control group (E) receiving 500 mcg Estrumate. Cows received their respective treatments in a single dosage on Day 7, 8 or 9 of the estrous cycle (estrus = Day 0) and were artificially inseminated 12 h following the subsequent estrus. Blood samples were collected from all groups immediately prior to treatment and at 12-h intervals to 48 h post treatment and analyzed for progesterone (P(4)). Blood samples were collected at 3-h intervals from 24 to 72 h post treatment for animals in Group LIII and for 48 h (or observed estrus) starting on Day 19 of the estrous cycle for animals in Group C. These samples were analyzed for estradiol-17beta(E(2)), follicle stimulating hormone (FSH) and luteinizing hormone (LH). Treatment with Luprostiol at doses >/= 7.5 mg resulted in a synchronous estrous response during the first 5 d post treatment in 75 to 95% of cows treated. Luteal function, as evaluated by systemic P(4) concentration, paralleled results observed for estrous response. Treatment with a 15 or 30 mg dose of Luprostiol resulted in greater overall pregnancy rate at synchronized estrus. No biologically significant differences were found in blood levels of E(2), FSH or LH around the time of estrus between cows in Groups C and LIII. Results from these studies indicate treatment with Luprostiol at doses >/= 7.5 mg resulted in a synchronous estrus during the first 5 d after treatment. Pregnancy rates and endocrine changes were similar to those observed in control and Estrumate-treated cows.

Journal Article↗

The three wheeler (adult tricycle): an unstable, dangerous machine.

Three-wheel motor vehicular accidents are a common occurrence, yet we found little publicity or published research dedicated to exposing the dangers of this popular recreational vehicle, and manufacturers have released few warnings. In a 3-year period, 125 patients were seen in the emergency department in one east Alabama referral area, a far higher rate of accidents than caused by other similar types of vehicles. The most common mechanism of these accidents was rollover of the machine; fractures were the most frequent injury suffered. The very young are common victims. Accident prevention must begin with education of both parents and children about the potential dangers of three-wheelers--they are, indeed, dangerous, unstable machines.

Acceleration↗

Response of HDL cholesterol, apoprotein A-I, and LCAT to exercise withdrawal.

The effect of short-term exercise withdrawal on plasma lipoproteins, apoprotein A-I (Apo A-I), and lecithin:cholesterol acyltransferase (LCAT) was studied in moderately trained lifestyle exercisers. Eight endurance-trained men, age 18-45 years (means = 29 years), withdrew from aerobic activity for 6 weeks, while an age and fitness-matched control group (n = 9) maintained normal exercise habits. A baseline period that included two blood samplings preceded the detraining intervention. Plasma total cholesterol (TCHOL), HDL cholesterol (HDL-C) and triglyceride (TG) levels were determined weekly. Other blood variables (HDL2-C, HDL3-C, Apo A-I, and LCAT), % fat, and aerobic capacity (VO2max) were measured pre-, mid-, and post-experiment. A two-way repeated measures analysis of variance (ANOVA) indicated that the 6-week exercise withdrawal period failed to elicit significant mean changes in any blood variable, % fat, or VO2max. Therefore, a short-term layoff from aerobic activity by moderately trained, chronic exercisers generally does not adversely affect the blood lipoprotein profile or aerobic capacity.

Adolescent↗

Tetanus and the aged.

Tetanus is primarily a disease of the aged. Even though the overall number of cases of tetanus has decreased since 1955, the number of cases of tetanus in people 50 years of age and older has remained constant. The national Center for Disease Control attributes the cases of tetanus in the aged to inadequate immunization levels. Tetanus is preventable and, theoretically, could be eradicated if the population was at an adequate immunization level. There are many reasons why older people are not adequately immunized. These reasons may include the inability to get to a health care facility due to physical disability or lack of transportation, ignorance of the importance of seeking health care for minor injuries, financial constraints and a knowledge deficit on the part of health care providers regarding the immunization needs of the aged. Health care providers can prevent tetanus in the aged through vigilance. All aged clients should be routinely assessed and immunizations updated as necessary. Tetanus will never be eliminated until universal active immunization has been achieved.

Aged↗

Allen's test: a tool for diagnosing ulnar artery trauma.

Trauma to the ulnar artery was first reported by Von Rosen in 1934. In more recent years this condition has been termed ulnar-artery thrombosis, hypothenar hammer syndrome or post-traumatic digital ischemia. Trauma to the ulnar artery is caused by the repeated use of the hand as a hammer in order to apply force to an object. Any person who presents with a history of trauma to the hypothenar eminence of the hand should be screened for ulnar artery thrombosis. This screening can easily and quickly be performed by the nurse utilizing the Allen test. Early detection of vascular insufficiency coupled with cessation of chronic trauma may help the client avoid reconstructive vascular surgery.

Arteries↗

Proximal muscle weakness in children.

In as many as half of the children referred to a muscle disease clinic, the original diagnosis is ultimately changed. Five cases histories are reviewed here in which Duchenne muscular dystrophy had been mistakenly diagnosed 3 to 12 years previously and the correct diagnosis was made only after repeat muscle biopsy or biopsy review. Four boys had diseases with a much better prognosis, and one boy did not have a muscle disease at all.

Biopsy↗

Reproduction in Duchenne dystrophy.

A man with Duchenne muscular dystrophy fathered two living children. He was 1 of 10 affected males in 5 generations. Clinical and genetic patterns, muscle biopsies, autopsy results, and serum enzymes were all compatible with the diagnosis of Duchenne muscular dystrophy. History, blood typing, and karyotypes indicated that he was the biologic father. This report gives confirmatory evidence that Duchenne dystrophy is transmitted as an X-linked defect.

Adolescent↗