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Biomedical subjects

C E Nemcovsky

Publications and source records attributed to C E Nemcovsky.

33 records · Page 2Linked to original sources

Transferring the occlusal and esthetic anatomy of the provisional to the final restoration in full-arch oral rehabilitations.

Provisional restorations are an excellent diagnostic instrument, especially in full-arch oral rehabilitations where no normal occluding contacts remain. Esthetics, phonetics, function, parafunction, and dysfunction after evaluation and acceptance through clinical trial with the provisional restorations should be accurately transferred to the final restorations to ensure the same clinical success. This article presents a sequence of clinical procedures that enables a methodical and controlled transfer of the morphology of the provisional restorations to the final ones in full-arch oral rehabilitations.

Dental Occlusion, Centric↗

Erosion-abrasion lesions revisited.

Oral-hygiene-related abrasion lesions usually occur in patients over 30 years of age. Although abrasions and idiopathic erosions are different regressive alterations of the teeth, the clinical diagnosis is not always evident. Abuse of oral-hygiene devices and abrasive dentifrices can cause dental and gingival abrasions, but their role in the etiology of these lesions should be established clearly before a precise diagnosis is made. This largely influences treatment implications and expectations. This article clarifies the definitions, etiology, pathogenesis, clinical aspects, and treatment of abrasions and similar clinical lesions.

Adolescent↗

Orthodontic tooth movement following guided tissue regeneration: report of three cases.

This report presents three patients with advanced adult periodontitis and in which orthodontic tooth movement was performed subsequent to guided tissue regeneration procedures. Clinical follow-up showed a mean 3.3-mm attachment gain in the deepest preoperative probing depth sites, and radiographs revealed bone fill following guided tissue regeneration procedures with resorbable and nonresorbable membranes, with and without the use of demineralized freeze-dried bone allograft. Orthodontic tooth movement into the regenerated areas was successful. The feasibility of orthodontic tooth movement following successful regenerative procedures is discussed.

Adult↗

Variation of skin surface temperature over the masseter muscles in patients with myofascial pain following occlusal splint treatment.

The skin surface temperature (SST) over the masseter muscles was measured in 19 patients suffering from myofascial pain (MP) and 20 controls who had no history of any craniomandibular disorder. Seven measurements with intervals of 2 weeks were carried out. MP patients received an occlusal stabilization appliance during their second visit as their only treatment. Clinical symptoms, including muscle sensitivity to palpation, jaw movement and general feeling were evaluated at each visit and compared to baseline. The results indicated that SST in the control group remained almost unchanged throughout the study. In the MP group, the mean temperature decreased during the study after initial treatment. Accordingly, there was a probability of 88.5% that the occlusal appliance treatment in the MP group would cause a decrease of SST over the masseter muscle. A significant relationship between clinical improvement and a decrease of SST was found in the MP group. Temperature recordings with certain limitations could be an objective assessory tool in diagnosis and follow-up of patients with myofascial pain.

Adolescent↗

Transferring provisional restorations to final master casts.

Many principles guide preparation and fitting of provisional restorations. Their importance as a diagnostic tool is considered. Aesthetic, phonetic, functional, parafunctional and dysfunctional factors after evaluation in the provisional restorations have to be transferred to the master cast to incorporate them into the final restoration. A method for transferring morphology of provisional restorations to the master cast through preparation of a wax analogue fixed partial denture is presented. This method is precise, practical, suitable for most rehabilitation cases, and not clinically time-consuming since most stages are carried out in the dental laboratory.

Dental Casting Technique↗

Investigation of the effects of a variable lateral guidance incline on the pantronic registration of mandibular border movement: Part II.

This study was designed to test the hypothesis that changes in lateral guidance inclination could affect the condylar registrations in the recordings of an electronic pantography. In seven healthy subjects, pantronic registrations of immediate side shift, progressive side shift, and orbiting and protrusive condylar paths were recorded with lateral anterior guidance inclinations of 0, 20, 30, 45, and 60 degrees from the same pin height. Analysis of variance with repeated measures showed a significant decrease in the immediate side shift (p 0.016) and the progressive side shift (p 0.051) as the lateral guidance angle increased and no significant effect on the orbiting registrations. These observations, together with those from other studies, suggest that the concept of fabricating the working-side tooth guidance exactly according to instrument condylar settings (which themselves may be subject to a variable recording lateral anterior guidance) appears untenable and demands further study.

Adult↗

A comparative study of three therapeutic modalities in a temporomandibular disorder (TMD) population.

A comparative study of three treatment modalities, pharmacologic, occlusal appliance, and their combined use, was conducted to test their therapeutic efficacy on 61 temporomandibular disorder (TMD) patients. Alprazolam (Xanax) was used for the pharmacologic treatment; the occlusal appliance therapy consisted of a flat maxillary stabilization splint. Of the 61 patients, 19 received Alprazolam, 30 received occlusal appliance therapy, and 12 received combined therapy. Subjects were examined at two-week intervals for two months. Only 42 patients attended all follow-up visits. Eight parameters were studied: severity of pain, periodicity of pain, self-evaluated stress, muscle sensitivity to palpation, joint sensitivity to palpation, joint noises, limitation of opening, and limitation of lateral movement. No significant difference was found between the treatment modalities for most of the parameters. All three proved to be effective. Alprazolam increased the restricted mandibular movement, was least effective on joint sensitivity to palpation, and had no effect on joint noises. The combined treatment approach not only failed to prove superior to the other treatments, but showed less improvement in some parameters, possibly due to the small sample.

Alprazolam↗

A comparative study of the stereognathic ability between patients with myofascial pain dysfunction syndrome and a control group.

This study compared the stereognathic ability of two groups of subjects. One group comprised 35 myofascial pain dysfunction syndrome (MPDS) subjects and the other, 30 control non-MPDS subjects. Thirteen different acrylic resin shapes were used for oral and manual identification. No statistically significant difference was found between the two groups in the accuracy of identification, time for identification and their ratio. The results indicate no difference in stereognathic ability between the MPDS and the control group.

Adult↗

Custom overdenture retainer.

A simple technique for fabricating stud overdenture retainers in the form of custom attachment castings with teflon retention discs has been described. This system allows for selective placement of the retention sphere on the root surface and control of retention through the size of the retention sphere. Using transfer location projections, exact transfer of the castings to the working model is possible. When necessary, the teflon discs may easily be replaced at the chairside.

Acrylic Resins↗

Functional disturbances of the masticatory system in an elderly population group.

The purpose of this study was to determine the prevalence of craniomandibular disorders in a geriatric population in Israel, and to study morphometric and functional parameters as well. One hundred ten elderly subjects (61-90 years old) were interviewed and examined clinically for the following parameters: general health history, dental comfort and masticatory performance, anthropometric measurements, functional performance of the stomatognathic system, dental status, static and dynamic occlusion, and signs and symptoms of craniomandibular disorders. The results indicate that (1) loss of hearing was the most common debilitating functional disturbance reported, with rheumatoid or rheumatoid-like chronic diseases also common among this age group; (2) chewing performance was compromised and tongue thrust was common; (3) range of mandibular movement was decreased; (4) prevalence of signs and symptoms of craniomandibular disorders in the elderly were compatible with or higher than those in younger subjects, but the older individuals were not disturbed by the problem enough to seek help; (5) there was no association between impaired general health and the prevalence of craniomandibular disorders; and (6) interocclusal distance was large and negatively related to the lower third of the face and positively related to the presence of full dentures.

Adult↗

Healing of dehiscence defects at delayed-immediate implant sites primarily closed by a rotated palatal flap following extraction.

In 21 patients, 28 maxillary teeth were extracted because of periapical or periodontal infection, root fracture, or untreatable caries. A rotated palatal flap procedure was used to achieve primary soft tissue closure over extraction sites. At 5 to 7 weeks postextraction, 28 implants were placed. Buccal dehiscence-type defects were treated with guided bone regeneration procedures using bovine bone mineral and resorbable collagen membranes. Mean defect area at the time of implant placement (23.7 mm2, SD 11.49) was significantly reduced at uncovering (0.7 mm2, SD 0.99). The mean percentage of defect reduction (clinical bone fill) was 97% (SD 4.26). Implants placed in compromised sites shortly postextraction according to the presented 2-stage protocol gave good short-term clinical results.

Adult↗

Clinical coverage of dehiscence defects in immediate implant procedures: three surgical modalities to achieve primary soft tissue closure.

In 61 patients, 61 consecutive implants were placed immediately after extraction of one anterior or premolar maxillary tooth. One of 3 surgical approaches based on rotated full (RPF) or rotated split (RSPF) palatal flaps, with and without the use of barrier membranes to enable primary soft tissue closure, was applied. A bovine bone mineral graft was used in all cases. At the time of implant placement, the distance between the most apicobuccal alveolar crestal bone and the coronal aspect of the implant body was measured; this was measured again at second-stage surgery. All implants appeared clinically stable. The buccal crestal bone gain was statistically significant for all groups (RPF = 2 mm, RSPF = 1.6 mm, RSPF with membrane = 3.7 mm) (P < .001). Analysis of covariance showed a significant covariant for preoperative measurements; however, this was not significant between groups.

Alveolar Process↗

Spontaneous early exposure of submerged endosseous implants resulting in crestal bone loss: a clinical evaluation between stage I and stage II surgery.

Spontaneous early exposure of submerged implants during the osseointegration healing phase may be a harmful factor that results in early crestal bone loss around the implants. The objective of this study was to assess the effect of spontaneous early exposure on crestal bone loss around submerged implants, with special attention given to the relationship between the degree of exposure and the amount of peri-implant bone loss. Crestal bone level relative to the shoulder of the implant was measured at the time of placement and at the time of exposure 4 to 5 months later. During the period between stage I and stage II surgery, implant sites were observed, and each implant site in which spontaneous early exposure was detected was recorded. Perforations were classified according to the degree of implant exposure from Class 0 (no perforation) to Class IV (complete exposure). Measurements from 206 implants in 64 patients produced 85 groups valid for statistical comparison; each of these contained at least 2 lesions of different types. There was a statistically significant difference between bone loss associated with intact mucosa (Class 0) and Class I, Class II, and Class III lesions, and between Class I and II lesions. There were no significant differences between Class I and III and between Class II and III. In Class II and III lesions, there was more bone loss associated with the buccal aspect of the implants. Of the 115 perforated sites, 10 were associated with bone loss exceeding 2 mm, 2 presented 3 to 4 mm bone loss, 1 showed more than 4 mm, and 1 displayed more than 5 mm. In view of the clinical implications that spontaneous early exposure may have on the success of osseointegration, prematurely partially exposed implants should be exposed as soon as possible after the perforation is observed.

Alveolar Bone Loss↗

Expression of matrix metalloproteinase 2 and heat shock protein-72 in immobilized muscle in rats.

Metalloproteinases (MMPs) are proteolytic enzymes that function in the extracellular matrix to degrade connective tissues. While it is clear that certain induced skeletal muscle pathologies promote increased expression of MMP-2 and heat shock protein- 72 (HSP-72), the relationship between muscle disuse and expression of MMP-2 and HSP-72 in muscles is unknown. These experiments tested the hypothesis that knee immobilization induced expression of MMP-2 and HSP-72 is disuse-dependent in a way that short-term joint immobilization increases HSP-72 expression, whereas long-term joint immobilization increases MMP-2 expression in skeletal muscles. Male rats (8 months old) completed 1, 2, 3, and 4 weeks of knee joint immobilization. Muscle mRNA and protein levels of MMP-2 and HSP-72 were assessed in Gastrocnemius (Gast), Superficial and Deep Quadriceps, and Soleus (Sol) muscles by reverse transcriptase-polymerase chain reaction and western blotting, respectively. Results reveal that during the first two weeks of immobilization there is increased protein levels of HSP-72 and expression of mRNA of HSP-72 mainly in slow twitch muscle fibers. However, 3 and 4 weeks of joint immobilization increased both mRNA and protein levels of MMP-2 in skeletal muscles containing a high percentage of fast type II fibers (i.e., Gast and superficial quadriceps). These results support the hypothesis that different periods of muscle disuse induced different proteins expression, and that the influence of joint immobilization on the expression of HSP-72 in the short-term, and MMP-2 in the long ran is associated to fiber types.

Animals↗