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Biomedical subjects

C Dubost

Publications and source records attributed to C Dubost.

At least 433 records · Page 24Linked to original sources

[Atypical pulmonary localization of Takayasu's disease].

Takayasu's disease preferentially involves the aorta and its branches. Extension along the pulmonary artery is much more rare. The case presented here is that of a young woman presenting with bilateral involvement of the pulmonary arteries, consisting of hypoplasia on the right and dilatation on the left. The investigation was completed by a study of the collateral vascularization in the right lung and by a lung scan. Right ventricular failure was the condition which led to the diagnosis of the disease. The abdominal aorta and the right renal artery are also involved, which led us to consider the pulmonary lesions as being part of Takayasu's disease. The aortic and renal involvements were asymptomatic and there were no signs of progression of the disease.

Adult↗

[Surgical treatment of primary hyperparathyroidism in patients over 70 years of age].

Hyperparathyroidism is a frequent, often fortuitous finding in elderly people. Our series includes 103 patients over 70 years of age, 90 of whom were operated upon. Elderly patients rarely are without any symptom, but it is difficult, prior to surgery, to associate their clinical disorders with hyperparathyroidism. Our results show that surgical treatment is virtually without danger and that most patients were distinctly improved. The innocuousness and effectiveness of surgery in these patients, as well as the absence of medical treatment are as many reasons to widen the indications of the surgical approach.

Aged↗

Traumatic rupture of the thoracic aorta with reference to 34 operated cases.

34 cases of traumatic rupture of the aortic isthmus have been operated on since 1963: 14 acute ruptures and 20 secondary false aneurysms. Diagnosis was confirmed by aortography. A special feature seen in cases of total transsection is described. Partial extracorporeal bypass was used in 29 cases and direct cross-clamping in 5 cases. Two techniques were used: direct end-to-end anastomosis in 9 patients and Dacron graft interposition in 25 cases. Primary end-to-end anastomosis more often was used in cases of early operation and partial rupture. Hospital mortality was 2 patients in the group of acute ruptures and 0 patient in chronic false aneurysm group. It was related to brain damage or sequelae of prolonged shock. Post-operative course was uneventful but 4 cases of respiratory failure and 4 cases of neurologic disturbances (2 brain dysfunctions and 2 spinal cord dysfunctions). These complications were transient and the patients recovered without sequelae. Clinical results have been recently appreciated in every long-term survivor (mean follow-up: 5 years) and are excellent. Angiographic controls undergone in 10 patients have shown no abnormalities.

Accidents, Traffic↗

Surgery for aortic dissection: 53 operated cases with 32 in the acute phase.

53 cases of aortic dissections were operated on between 1961 and 1975 in the Service of Cardiovascular Surgery at the Broussais Hospital, Paris (Prof. Ch. Dubost). The present study deals with 32 cases operated on in the acute phase. 31 originated in the ascending aorta and 1 in the descending aorta. Operative mortality was 50% (16/32), 4 patients died immediately following sternotomy. Operation consisted in replacement of the ascending aorta for the majority of type I and II dissections. When aortic insufficiency was present, a simple resuspension procedure was effective in 50% of cases. The authors prefer early operative intervention in type I and II dissections and medical treatment in type III dissections.

Acute Disease↗